Results 81 to 90 of about 315,665 (286)

ESCRT-III is recruited by human herpesvirus 6A nuclear egress complex to promote nuclear egress of the nucleocapsid

Journal of Virology
Herpesviruses replicate their genomes and package them into capsids within the host cell nucleus. These capsids must then translocate from the nucleus to the cytoplasm through a process designated nuclear egress. The virus-encoded nuclear egress complex (
Aila Gulijiahani, Jun Arii, Vuk Isakovic, Jing Rin Huang, Yasushi Kawaguchi, Yasuko Mori   +5 more
doaj   +1 more source

Evidence for interactions between the mitochondrial import apparatus and respiratory chain complexes via Tim21-like proteins in Arabidopsis.

Frontiers in Plant Science, 2014
The mitochondrial import machinery and the respiratory chain complexes of the inner membrane are highly interdependent for the efficient import and assembly of nuclear encoded respiratory chain components and for the generation of a proton motive force ...
Monika Weronika Murcha, Szymon eKubiszewski-Jakubiak1, Yan eWang, James eWhelan   +3 more
doaj   +1 more source

Zonula occludens 2 and Cell-Cell Contacts Are Required for Normal Nuclear Shape in Epithelia

Cells, 2021
MAGUK protein ZO-2 is present at tight junctions (TJs) and nuclei. In MDCK ZO-2 knockdown (KD) cells, nuclei exhibit an irregular shape with lobules and indentations.
Christian Hernández-Guzmán, Helios Gallego-Gutiérrez, Bibiana Chávez-Munguía, Dolores Martín-Tapia, Lorenza González-Mariscal   +4 more
doaj   +1 more source

Successive translocation into and out of the mitochondrial matrix [PDF]

, 1987
We investigated the import and sorting pathways of cytochrome b2 and cytochrome c1, which are functionally located in the intermembrane space of mitochondria.
Alt, Appleby, Bradford, Böhni, Chen, Conboy, Daum, Dowhan, Duffaud, Eilers, Fujiki, Gabellini, Gabellini, Gasser, Gasser, Gubler, Guiard, Hallermayer, Harmey, Hartl, Hartl, Hartl, Hauska, Hay, Hayashi, Horwich, Hurt, Hurt, Hurt, Kaput, Kolanski, Krieg, Laemmli, Lewin, Li, McAda, Miura, Ohashi, Pelham, Perara, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pratje, Riezmann, Rottier, Römisch, Sadler, Schatz, Schleyer, Schleyer, Schmidt, Schmidt, Schwaiger, Simon, Smeekens, Stueber, Talmadge, Teintze, van Loon, van Loon, van Loon, Voordouw, Zimmermann, Zwizinski   +67 more
core   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

An ESCRT-LEM protein surveillance system is poised to directly monitor the nuclear envelope and nuclear transport system

eLife, 2019
The integrity of the nuclear membranes coupled to the selective barrier of nuclear pore complexes (NPCs) are essential for the segregation of nucleoplasm and cytoplasm.
David J Thaller, Matteo Allegretti, Sapan Borah, Paolo Ronchi, Martin Beck, C Patrick Lusk   +5 more
doaj   +1 more source

Gcn5 histone acetyltransferase is present in the mitoplasts [PDF]

, 2019
In Saccharomyces cerevisiae the Lysine-acetyltransferase Gcn5 (KAT2) is part of the SAGA complex and is responsible for histone acetylation widely or at specific lysines.
De Luca, Veronica, Filetici, Patrizia, Francisci, Silvia, Leo, Manuela, Montanari, Arianna   +4 more
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Cell Cycle Dynamics of the Nuclear Envelope

The Scientific World Journal, 2003
The nuclear envelope (NE) consists of an inner and an outer membrane, nuclear pore complexes, and the underlying nuclear lamina, a filamentous scaffold structure formed by lamins.
Roland Foisner
doaj   +1 more source

Normative Data and Minimally Detectable Change for Inner Retinal Layer Thicknesses Using a Semi-automated OCT Image Segmentation Pipeline [PDF]

, 2019
Neurodegenerative and neuroinflammatory diseases regularly cause optic nerve and retinal damage. Evaluating retinal changes using optical coherence tomography (OCT) in diseases like multiple sclerosis has thus become increasingly relevant.
Asseyer, Susanna, Ayadi, Noah, Bereuter, Charlotte, Brandt, Alexander Ulrich, Gawlik, Kay, Kadas, Ella Maria, Mikolajczak, Janine, Motamedi, Seyedamirhosein, Paul, Friedemann, Zimmermann, Hanna G.   +9 more
core   +2 more sources