Results 71 to 80 of about 3,326,595 (262)

Sequences within the C Terminus of the Metabotropic Glutamate Receptor 5 (mGluR5) Are Responsible for Inner Nuclear Membrane Localization*

Journal of Biological Chemistry, 2017
Traditionally, G-protein-coupled receptors (GPCR) are thought to be located on the cell surface where they transmit extracellular signals to the cytoplasm.
Ismail Sergin, Y. Jong, S. Harmon, Vikas Kumar, K. O'Malley   +4 more
semanticscholar   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Interactions between nuclear lamins and their binding partners in EDMD fibroblasts [PDF]

, 2003
Lamins are components of the nuclear lamina and are divided In A and B-types, which Interact with proteins of the inner nuclear membrane like emerin.
Alvarez-Reyes, Mauricio
core  

Biogenesis of the inner membrane complex is dependent on vesicular transport by the alveolate specific GTPase Rab11B [PDF]

, 2010
Apicomplexan parasites belong to a recently recognised group of protozoa referred to as Alveolata. These protists contain membranous sacs (alveoli) beneath the plasma membrane, termed the Inner Membrane Complex (IMC) in the case of Apicomplexa.
Langsley, G, Bernardo J. Foth, Ferguson, D.J. P., Ferguson, DJ, Markus Meissner, David J. P. Ferguson, Foth, B.J., Carolina Agop-Nersesian, Langsley, G., Agop-Nersesian, C, Meissner, M, Saskia Egarter, Meissner, M., Egarter, S., Sibley, L.D., Egarter, S, Bernardo J Foth, Gordon Langsley, Agop-Nersesian, C., David J P Ferguson, Foth, BJ   +20 more
core   +1 more source

Parvoviruses cause nuclear envelope breakdown by activating key enzymes of mitosis. [PDF]

PLoS Pathogens, 2013
Disassembly of the nuclear lamina is essential in mitosis and apoptosis requiring multiple coordinated enzymatic activities in nucleus and cytoplasm. Activation and coordination of the different activities is poorly understood and moreover complicated as
Manvi Porwal, Sarah Cohen, Kenza Snoussi, Ruth Popa-Wagner, Fenja Anderson, Nathalie Dugot-Senant, Harald Wodrich, Christiane Dinsart, Jürgen A Kleinschmidt, Nelly Panté, Michael Kann   +10 more
doaj   +1 more source

Getting To and Through the Inner Nuclear Membrane During Herpesvirus Nuclear Egress

Current Opinion in Cell Biology, 2017
Herpesviruses, like most DNA viruses, replicate and package their genomes into capsids in the host cell nucleus. Capsids then transit to the cytoplasm in a fascinating process called nuclear egress, which includes several unusual steps: Movement of ...
M. Lye, Adrian R. Wilkie, D. Filman, J. Hogle, D. Coen   +4 more
semanticscholar   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Dissecting the telomere-inner nuclear membrane interface formed in meiosis

Nature Structural & Molecular Biology, 2017
Tethering telomeres to the inner nuclear membrane (INM) allows homologous chromosome pairing during meiosis. The meiosis-specific protein TERB1 binds the telomeric protein TRF1 to establish telomere–INM connectivity and is essential for mouse fertility ...
D. Pendlebury, Y. Fujiwara, V. M. Tesmer, E. Smith, Hiroki Shibuya, Yoshinori Watanabe, J. Nandakumar   +6 more
semanticscholar   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

ESCRT-III is recruited by human herpesvirus 6A nuclear egress complex to promote nuclear egress of the nucleocapsid

Journal of Virology
Herpesviruses replicate their genomes and package them into capsids within the host cell nucleus. These capsids must then translocate from the nucleus to the cytoplasm through a process designated nuclear egress. The virus-encoded nuclear egress complex (
Aila Gulijiahani, Jun Arii, Vuk Isakovic, Jing Rin Huang, Yasushi Kawaguchi, Yasuko Mori   +5 more
doaj   +1 more source