Results 41 to 50 of about 2,738,380 (292)

Does Knowledge Stickiness Affect a Firm’s Innovation Capability? Empirical Evidence From Indonesian Furniture SMEs

Gadjah Mada International Journal of Business, 2012
This study aims to examine the relationship between knowledge stickiness and a firm’s innovation capability in the context of developing countries, i.e., Indonesia. The main research question addressed by this study is: does knowledge stickiness affect a
Nurul Indarti
doaj   +1 more source

Determinants of SMEs’ product innovation performance in Malaysia: an extended model

Cogent Business & Management, 2022
This paper analyzes the organizational capabilities associated with new product development of SMEs in manufacturing companies with indicators such as administrative capabilities, functional capabilities (R&D, manufacturing, and marketing), and ...
Maha Mohammed Yusr, Olayemi Abdullateef Aliyu, Amira Khattak, Maruf Gbadebo Salimon, Shoaib Muhammad   +4 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

How the Interaction of Big Data Analytics Capabilities and Digital Platform Capabilities Affects Service Innovation: A Dynamic Capabilities View

IEEE Access, 2020
The emergence of big data analytics capability (BDAC) and the development of service innovation have aroused the interest of scholars and practitioners in exploring the mechanism of BDAC-service innovation value chain from the inside.
Xiaohong Xiao, Qinghong Tian, Hongyi Mao
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

RESOURCES, CAPABILITIES AND COMPETENCES FOR ECO-INNOVATION

Technological and Economic Development of Economy, 2015
The existing literature on the determinants for the development and adoption of ecoinnovations has generally focused on analysing the influence of business strategies and external drivers (public policy and stakeholder impacts) on innovation processes in firms.
Del Río, Pablo, Carrillo-Hermosilla, Javier, Könnölä, Totti, Bleda, Mercedes   +3 more
openaire   +5 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Innovation challenges of utilities in informal settlements: Combining a capabilities and regime perspective [PDF]

, 2019
The provision of basic services is falling short in informal settlements of cities in the Global South. In particular, public utilities have had difficulties expanding their services to the urban poor.
Gebauer, Heiko, van Welie, Mara J., Gebauer, Heiko,, Truffer, Bernhard, Mara J. van Welie, Bernhard Truffer, van Welie, Mara J.,, Heiko Gebauer, Truffer, Bernard,   +8 more
core   +1 more source