Results 51 to 60 of about 865,779 (311)

Roles of Capabilities and Leader Characteristics in SME Digital Innovation [PDF]

, 2016
Digital technology (viewed as the combination of information, computing, communication, and connectivity technology) is impacting on the marketplaces that SMEs operate in. Yet, little is understood about how these businesses are adapting to, and adopting,
Budhathoki, Tribikram, Molinillo-Jimenez, Sebastian, Pera, Rebecca, Quinton, Sarah   +3 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The Effect of the Knowledge Management Processes Capability on Innovation Activities in the Mexican Industry

Administrative Sciences, 2023
Mexican industrial organizations focus their efforts on the development of new products and processes, including breakthrough technology. Few studies have focused on the analysis of this corporate effort. After an in-depth theoretical review, it has been
José Guadalupe Flores López, Carlos Armando Jacobo Hernández, Beatriz Alicia Leyva Osuna, Luis Alberto Limón Valencia   +3 more
doaj   +1 more source

Frugal innovation capabilities: conceptualization and measurement

Prometheus, 2021
Firms in emerging markets are rapidly developing frugal innovation capabilities (FICs) in order to harness the growth potential of these markets. Researchers have explored this frugal innovation phenomenon through case studies of such firms.
Avinash Shivdas, Saswata Barpanda, Soumya Sivakumar, Ram Bishu   +3 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The consequences of innovation failure: An innovation capabilities and dynamic capabilities perspective

Technovation, 2023
Organizations engage with innovation by leveraging their innovation capabilities and dynamic capabilities. In this study, we examined how organizational innovation capabilities and dynamic capabilities can influence organizational performance, taking into account cases when innovation projects do not yield beneficial outcomes to organizations. Building
Chatterjee S., Chaudhuri R., Mariani M., Fosso Wamba S.   +3 more
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The impact of enterprises’ scientific capabilities on innovation performance: evidence from an empirical analysis and simulation model

Humanities & Social Sciences Communications
As the interaction between science and technology intensifies, the role of science in driving technological innovation has become increasingly significant.
Weijie Zhu, Wucheng Han, Ruoyu Lu, Jiasu Lei   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Dimensions of Alignment between Digital Capability and Innovation Strategy in Petrochemical Industry [PDF]

مطالعات مدیریت کسب و کار هوشمند
The reduction of profit margins and the disappearance of past competitive advantages have pushed companies in Petrochemical industries toward innovation by utilizing digital capabilities.
Soroush Ghazinoori, Sohrab Aghazade Masroor, Mohamad Naghizadeh, Mojtaba Hajian Heidary   +3 more
doaj   +1 more source