Results 71 to 80 of about 2,738,380 (292)
Brite innovation survey : executive summary [PDF]
, 2005 This report summarises the fi ndings of an innovation survey\ud of the Australian construction industry undertaken by the\ud BRITE Project of the CRC for Construction Innovation in\ud 2004.
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
, 2017 This study seeks to answer two key questions about the front-end innovation: when do idea generation activities involving internal and external partner’s payoff, and which organizational capabilities support idea generation activities for achieving high ...
Gama, Fabio, Parida, Vinit
core +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Changes in the French Defence Innovation System: New roles and capabilities for the Government Agency for Defence. [PDF]
Defence innovation systems are structured around two main groups of players that interact in the development of complex programmes: the state (the client and the government agency) and the systems integrators.
Lazaric, Nathalie +2 more
core +2 more sources
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Knowledge Capabilities, Communication and Innovation in Beef Cattle Farm Enterprises [PDF]
A capabilities perspective of farm level innovation in the beef cattle industry is presented using information economics. The knowledge capabilities of non-corporate beef cattle enterprises have two interrelated components: the knowledge generated from ...
Noble, Chris
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Do we teach what we research? unfolding absorptive capacity,open innovation, management innovation and clusters [PDF]
, 2012 El presente Taller de Estrategia Empresarial, es un workshop internacional organizado por la Sección de Estrategia Empresarial de la asociación ACEDE, que se celebrará en Valencia en enero de 2012.
Hervás Oliver, Jose Luis
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Capabilities and innovation enablers of the value proposition of actors in platform businesses [PDF]
مطالعات مدیریت راهبردیIntroductionThe emergence of digital platforms is increasing as a result of technology development [4]. Although organizations consider digital platforms as a very important way to achieve technological innovation, the platform companies themselves also ...
Maryam Nematollahi Sarvestani +2 more
doaj +1 more source