Results 91 to 100 of about 280,439 (265)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Perceived blame risk and innovative behavior among Chinese grassroots civil servants: the roles of career calling and perceived organizational support

Frontiers in Psychology
IntroductionGrassroots civil servants operate at the forefront of public service, where they directly address complex social issues and exercise substantial discretion.
Huan Zhao, Xingyu Zhang, Peifeng Chen, Jinfeng Zhang, An Hu   +4 more
doaj   +1 more source

Innovative behavior as a mediator

Journal on Innovation and Sustainability RISUS
This study examines the impact of self-efficacy, supportive work environment, individual creativity, and perceived organizational support on innovative behavior and employee performance among graphic design employees in digital printing companies across East Java, Indonesia. Data were collected through a survey of 160 graphic design employees from five
openaire   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Exploration Capabilities, Digital Competence, Innovation, and Sustainable Competitive Advantage: Does Entrepreneurial Agility Matter?

Jurnal Aplikasi Manajemen
Entrepreneurial agility is a crucial factor in Indonesia's online business. The sector is important in achieving the 2030 Sustainable Development Goals (SDGs), and supports the digital economy focus in RIRN 2017-2045.
Mokhamad Arwani, Maskudi, Susetyo Darmanto, Didik Ariyanto   +3 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

The moderating role of knowledge sharing behavior between innovative behavior and nursing competency: a cross-sectional study

Frontiers in Psychology
BackgroundThe association between nurses’ innovative behaviors and nursing competence has been demonstrated. However, the role of knowledge-sharing practices has been overlooked.
Lu Bian, Yuan Qian, Yujuan Lou, Mingxia Xia, Yun Zhou, Ying Zhang, Longhua Yuan, Dandan Xia   +7 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Influence of emotional intelligence level of ICU nurses on innovative behavior

Huli yanjiu, 2016
tObjective:To know about the influence situation of the emotional intelligence level of ICU nurses on innovative behaviors.Methods：A total of 300 ICU nurses in 4 third grade A hospitals in Harbin city were randomly selected as the research objects,then ...
Wei Bailing
doaj  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source