Results 101 to 110 of about 378,797 (150)

SIRT5-mediated desuccinylation of PPA2 enhances HIF-1alpha-dependent adaptation to hypoxic stress and colorectal cancer metastasis

The EMBO Journal
Metastasis is the primary cause of death in patients with colorectal cancer (CRC). Hypoxia is a hallmark of solid tumors that promotes cellular metabolic adaptation and dissemination. However, the mechanisms linking hypoxia-regulated metabolic adaptation
Xiang Zhang, Yuqin Di, Youpeng Wang, Jiale Qin, Lvlan Ye, Xiangqiong Wen, Zunfu Ke, Ziyang Wang, Weiling He   +8 more
doaj   +1 more source

X-ray Crystallography and Electron Paramagnetic Resonance Spectroscopy Reveal Active Site Rearrangement of Cold-Adapted Inorganic Pyrophosphatase. [PDF]

Sci Rep, 2020
Horitani M, Kusubayashi K, Oshima K, Yato A, Sugimoto H, Watanabe K.   +5 more
europepmc   +1 more source

Biochemical and Immunological Studies of an Inorganic Pyrophosphatase from Second Stage Larvae of Ascaris suum

, 1965
The present study was undertaken with the following objectives in mind. 1. To survey the relative abundance of some of the soluble enzymes of Ascaris second stage larva. 2. To isolate and characterize and enzyme vital for parasitic growth and development.
Mishra, Nirmal K.
core  

[Effect of inorganic pyrophosphatase PPA1 on proliferation and apoptosis of abnormal naive cells in acute B-lymphocytic leukemia]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Hu CX, Zhang XH, Wang XJ, Dai JJ, Zhang F, Wei XD, Lyu XD.   +6 more
europepmc   +1 more source

Clinical significance and functional validation of inorganic pyrophosphatase in diffuse large B cell lymphoma in humans. [PDF]

Cytotechnology, 2018
Li L, Aruna, Luo D, Jin A.
europepmc   +1 more source

Alendronate repositioning as potential anti-parasitic agent targeting Trichinella spiralis inorganic pyrophosphatase, in vitro supported molecular docking and molecular dynamics simulation study. [PDF]

BMC Chem
Hanafy MA, Nassar DA, Zahran FM, Mohammed MMD.   +3 more
europepmc   +1 more source

Archaeal Inorganic Pyrophosphatase Displays Robust Activity under High-Salt Conditions and in Organic Solvents. [PDF]

Appl Environ Microbiol, 2016
McMillan LJ, Hepowit NL, Maupin-Furlow JA.   +2 more
europepmc   +1 more source

Proteomic profiling identifies the inorganic pyrophosphatase (PPA1) protein as a potential biomarker of metastasis in laryngeal squamous cell carcinoma. [PDF]

Amino Acids, 2016
Bodnar M, Luczak M, Bednarek K, Szylberg L, Marszalek A, Grenman R, Szyfter K, Jarmuz-Szymczak M, Giefing M.   +8 more
europepmc   +1 more source

Role of Vacuolar H+-inorganic pyrophosphatase in tomato fruit development. [PDF]

J Exp Bot, 2012
Mohammed SA, Nishio S, Takahashi H, Shiratake K, Ikeda H, Kanahama K, Kanayama Y.   +6 more
europepmc   +1 more source

Involvement of reduced ENPP1 function in the pathogenesis of ossification of the posterior longitudinal ligament. [PDF]

JBMR Plus
Kimura S, Furukawa K, Irie K, Adachi N, Hoshino Y, Hidaka N, Kato H, Miyahara J, Oshima Y, Doi T, Nangaku M, Makita N, Tanaka S, Saito T, Ito N.   +14 more
europepmc   +1 more source