Endothelial cell-derived SSAO can increase MLC20 phosphorylation in VSMCs
Vascular hyporesponsiveness in the shock decompensation period is an important factor leading to death. Myosin light chain 20 (MLC20) is the main effector protein that regulates vascular reactivity.
Zhang Yuxing +5 more
doaj +1 more source
Induced overexpression of MARCH-1 in human macrophages altered to M2 phenotype for suppressing inflammation process [PDF]
Objective(s): The M1 macrophage is characterized by enhanced pro-inflammatory cytokines production, whereas macrophage (M2) has anti-inflammatory features.
Zivar Zangeneh +2 more
doaj +1 more source
The physiological expression of inducible nitric oxide synthase (iNOS) in the human colon [PDF]
Inducible nitric oxide synthase (iNOS) is expressed in the colonic epithelium in both inflammatory bowel disease and colorectal cancer. Nitric oxide (NO), the product of this enzyme, has been implicated in the pathogenesis of both conditions.
Hunter, JO +5 more
core +2 more sources
Liu S, Jiang J, Huang L, et al. Cancer Manag Res. 2019;11:8005–8022. We, the Editors and Publisher of Cancer Management and Research, have retracted the published article. Concerns were raised following the authors request to correct Figure 4.
Liu S +11 more
doaj
Preconditioning of isoflurane on spinal cord ischemia can increase the number of inducible nitric oxide synthase-expressing motor neurons in rat [PDF]
BackgroundSpinal cord ischemia with resulting paraplegia remains one of the most common complications after repair of thoracoabdominal aortic aneurysms or dissection.
Yun-Hee Sung +6 more
doaj +1 more source
Protective effect of Cupressus macrocarpa and Dioon edule against gentamicin-induced nephrotoxicity in rats [PDF]
Context: It has been reported that Cupressus macrocarpa Hartw. ex Gordon (Cupressaceae) and Dioon edule Lindl. (Zamiaceae) contain compounds with antioxidant and anti-inflammatory effects; therefore, they may exert a nephroprotective effect.
Ghada Mohammad Al-Ashmawy +1 more
doaj
Indexes of nitric oxide system in experimental antiphospholipid syndrome [PDF]
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by the presence of antibodies to negatively charged membrane phospholipids (aPL).
O. Z. Yaremchuk +5 more
doaj +1 more source
A long-term "memory" of HIF induction in response to chronic mild decreased oxygen after oxygen normalization [PDF]
Background Endothelial dysfunction (ED) is functionally characterized by decreased vasorelaxation, increased thrombosis, increased inflammation, and altered angiogenic potential, has been intimately associated with the progression and severity of ...
Ceriello, Antonio +6 more
core +3 more sources
Maslinic Acid Ameliorates Inflammation via the Downregulation of NF-κB and STAT-1
Maslinic acid (MA), a natural compound of the triterpenoid group derived from olive, prevents the generation of pro-inflammatory cytokines and oxidative stress.
Wonhwa Lee +3 more
doaj +1 more source
Expression of Inducible Nitric Oxide Synthase in Keratocystic Odontogenic Tumour and Variants of Ameloblastoma – A Comparative Study [PDF]
Introduction: The odontogenic keratocyst (OKC) is a histopathologiocally and behaviourally unique and specific entity. It is the most aggressive and recurrent of all the cysts and shows characteristics resembling both cyst and a tumour.
Diana.H +4 more
doaj +1 more source

