Results 161 to 170 of about 66,823 (327)
Microorganisms, 2017 Excessive intake of purine-rich foods elevates serum levels of uric acid. Animal and fish meats contain high amounts of inosine and its related purines, and the reduction of taking those purines is crucial for the improvement of serum uric acid levels ...
N. Yamada +6 more
semanticscholar +1 more source
Activating AMPK improves pathological phenotypes due to mtDNA depletion
The FEBS Journal, EarlyView.In a cellular model of mitochondrial disease characterized by progressive mitochondrial DNA (mtDNA) depletion, we found that advancing mitochondrial dysfunction triggers the early and specific activation of the mitochondria‐associated pool of AMP‐activated protein kinase (AMPK), a master regulator of energy homeostasis.
Gustavo Carvalho +14 more
wiley +1 more source
The Relationship of the Age of Rabbit Erythrocytes to the Effects of Inosine on their Osmotic Resistance12 [PDF]
, 1958 Ernst R. Jaffé +3 more
openalex +1 more source
The FEBS Journal, EarlyView.A targeted mass spectrometry‐based metabolomics assay was conducted to identify the impact of stress exposure on the regulation of biological stress pathways in the mdx mouse model of Duchenne muscular dystrophy. We demonstrated a broad shift in the circulating stress‐relevant plasma metabolome associated with stressful scruff handling that was ...
Erynn E. Johnson, James M. Ervasti
wiley +1 more source
Y12C mutation disrupts IMPDH cytoophidia and alters cancer metabolism
The FEBS Journal, EarlyView.IMPDH, the rate‐limiting enzyme for de novo GTP synthesis, can form polymers and cytoophidia to enhance activity by reducing GTP inhibition. In this study, a Y12C mutation in IMPDH2 was introduced via ABEmax base‐editing in human cancer cell lines to disrupt IMPDH polymerisation.
Chia‐Chun Chang +7 more
wiley +1 more source
Production of Guanosine-5′-Monophosphate and Inosine-5′-Monophosphate by Fermentation [PDF]
, 1966 A. L. Demain +4 more
openalex +1 more source
Bulletin of the Chemical Society of Japan, 1970 Nobuya Nagashima, Yoshihisa Suzuki
openaire +2 more sources
Journal of Periodontal Research, EarlyView.Metabolomic fingerprints analyzed from oral rinses are able to distinguish between severe periodontitis (stage III/IV) patients and non‐periodontitis controls. ABSTRACT Aims To explore the potential of metabolomic profiles of oral rinse samples to distinguish between patients with severe periodontitis (stage III/IV) and non‐periodontitis controls. This
Madeline X. F. Kosho +4 more
wiley +1 more source
Fluorescence of Adenine and Inosine Nucleotides. [PDF]
, 1963 Eva Walass +4 more
openalex +1 more source
Plant, Cell &Environment, EarlyView.ABSTRACT Bacteriophages impact soil bacteria through lysis, altering the availability of organic carbon and plant nutrients. However, the magnitude of nutrient uptake by plants from lysed bacteria remains unknown, partly because this process is challenging to investigate in the field.
Vlastimil Novak +10 more
wiley +1 more source