Results 171 to 180 of about 71,261 (330)

Fructose catabolism and its metabolic effects: Exploring host–microbiota interactions and the impact of ethnicity

The Journal of Physiology, EarlyView.
Abstract figure legend This graphical abstract is a schematic representation highlighting the interactions between dietary fructose, gut microbiota and ethnicity in shaping metabolic health. Abstract Important health disparities are observed in the prevalence of obesity and associated non‐communicable diseases (NCDs), including type 2 diabetes (T2D ...
Florine H.M. Westerbeke, Melany Rios‐Morales, Ilias Attaye, Max Nieuwdorp   +3 more
wiley   +1 more source

The Effects of Storage Conditions and Homogenisation Buffers on the Measurement of SOD, CAT and ADA Enzyme Activities in Cattle Liver

Veterinary Medicine and Science, Volume 11, Issue 4, July 2025.
It is important to accurately measure enzyme activities in research studies to evaluate parameters, and many factors may affect the results of the measurements. The aim of this study was to investigate the effects of storage conditions (time and temperature) and different homogenisation buffers (PBS or KCl) on the measurement of SOD, CAT and ADA enzyme
Burcu Menekse Balkan, Ogunc Meral, Bekir Cetintav, Hidayet Tutun, Guzin Ozkurt, Tevhide Sel   +5 more
wiley   +1 more source

Progress on the development of Class A GPCR‐biased ligands

British Journal of Pharmacology, Volume 182, Issue 14, Page 3249-3300, July 2025.
Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales, Magdalena M. Scharf, Marcel Bermudez, Attila Egyed, Rafael Franco, Olivia K. Hansen, Nadine Jagerovic, Jan Jakubík, György M. Keserű, Dóra Judit Kiss, Pawel Kozielewicz, Olav Larsen, Maria Majellaro, Ana Mallo‐Abreu, Gemma Navarro, Rubén Prieto‐Díaz, Mette M. Rosenkilde, Eddy Sotelo, Holger Stark, Tobias Werner, Laura M. Wingler   +20 more
wiley   +1 more source

Regulation of xanthine dehydrogenase in chick liver. Further experiments on the effects of inosine, actinomycin D and other factors [PDF]

, 1967
E. Della Corte, Fiorenzo Stirpe
openalex   +1 more source

Aspartate Is A Determinant of TNF‐α Biogenesis in Sub‐Saharan Africa: Insight Into the Pathogenesis of Noncommunicable Diseases

The FASEB Journal, Volume 39, Issue 11, 15 June 2025.
Proposed change in TNF‐α biogenesis with urbanization in sub‐Saharan Africa. Higher levels of aspartate in the rural population result in a NAD+ rich environment that favors stabilization of the endoplasmic reticulum (ER) membrane and suppressing TNF‐α.
Stephen W. Bickler, David M. Cauvi, Jack A. Gilbert, Romeo C. Ignacio, Emmanuel A. Ameh, Robert T. Schooley, Emilia V. Noormahomed   +6 more
wiley   +1 more source

ALSUntangled No. 37: Inosine* [PDF]

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2016
Paul Wicks, Terry Heiman-Patterson, Steve Kolb, Edor Kabashi, Yunxia Wang, Sabrina Paganoni, Kathy Mitchell, Megan Grosso, Josep Gamez, Emma Fixsen, Carlayne E. Jackson, Carmel Armon, Tahseen Mozaffar, Ginna Gonzalez, Chafic Karam, Kate Dalton, Jonathan D. Glass, Lisa Kinsley, Katherine Tindall, Lyle Ostrow, Mazen M. Dimachkie, Nazem Atassi, Steven Nash, Colin Quinn, Sith Sathornsumetee, Tulio E. Bertorini, Nicholas J. Maragakis, Dallas Forshew, Erik P. Pioro, Mark Bromberg, Gregory T. Carter, James Heywood, Michael Benatar, Larry Phillips, Orla Hardiman, Kevin Boylan, Christen Shoesmith, Jon Baker, L. P. Rowland, Dan Moore, Peter M Andersen, Richard Bedlack, James Caress, Alexander Sherman, Steven Novella, Janice Robertson, Eric J. Sorenson, Laurie Gutmann, Robin Conwit, John Ravits   +49 more
openaire   +3 more sources

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, Volume 19, Issue 6, Page 1668-1686, June 2025.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, Volume 19, Issue 6, Page 1707-1724, June 2025.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

Production of Inosine from Hydrocarbons by Corynebacterium petrophilum

, 1967
Takashi Iguchi, Riyoji Kodaira, Isao Takeda   +2 more
openalex   +4 more sources

Mutation of an inosine-producing strain of Bacillus subtilis to DL-methionine sulfoxide resistance for guanosine production [PDF]

, 1977
Hideo Matsui, Kenji Sato, Hitoshi Enei, Yoshinobu Hirose   +3 more
openalex   +1 more source