Results 181 to 190 of about 86,294 (302)
Abstract Studying how microenvironmental cues influence metabolic reprogramming can uncover mechanisms driving tumor progression. Using an in vitro model with proliferative stimuli of the in vivo lymph node niche (LN)—including interleukin‐21 (IL‐21)—we examined metabolic rewiring in chronic lymphocytic leukemia (CLL) cells. We found that the metabolic
Rosita Del Prete +16 more
wiley +1 more source
The Use of Inosine 5′-Monophosphate Dehydrogenase (IMPDH) in the Development of a New Liquid Homogeneous Enzyme Immunoassay Technology [PDF]
Allan R. Dorn +7 more
openalex +1 more source
Cardiac bioenergetic and metabolic perturbations in late‐stage Leigh syndrome. Whole‐body NDUFS4 loss severely impairs cardiac complex I activity and respiration, shifting reliance to complex II and reducing glycolytic, TCA, and amino acid‐derived energy‐generating substrates in the heart.
Karin Terburgh +2 more
wiley +1 more source
ABSTRACT The EmDia trial, designed to study the effects of the sodium glucose cotransporter‐2 (SGLT2) inhibitor empagliflozin on cardiovascular comorbidities in type 2 diabetes mellitus (T2DM) patients, has been investigated for short‐term metabolic alterations by a limited set of clinical assays. To expand on this data, we report on the development of
Fabian Schmitt +7 more
wiley +1 more source
Precision‐Engineered Poly(GMA‐EGDMA) Microspheres for Multifunctional Applications
The study presents multifunctional poly(GMA‐EGDMA) microspheres designed for advanced separation, catalysis, and biomedical engineering. Through precision synthesis and surface engineering, these microspheres exhibit excellent stability, tunable porosity, and high reactivity.
Imran Ali +3 more
wiley +1 more source
The Nucleoside Derivative 5′-O-Trityl-inosine (KIN59) Suppresses Thymidine Phosphorylase-triggered Angiogenesis via a Noncompetitive Mechanism of Action [PDF]
Sandra Liekens +6 more
openalex +1 more source
ABSTRACT DNA metabarcoding of zooplankton biodiversity is used increasingly for monitoring global ocean ecosystems, requiring comparable data from different research laboratories and ocean regions. The MetaZooGene Intercalibration Experiment (MZG‐ICE) was designed to examine1 and analyse patterns of variation of DNA sequence data resulting from multi ...
Leocadio Blanco‐Bercial +23 more
wiley +1 more source

