Results 181 to 190 of about 71,261 (330)
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
Molecular Oncology, Volume 19, Issue 6, Page 1737-1750, June 2025.This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu +7 more
wiley +1 more source
PharmaceuticalsAdenosine is a multifunctional nucleoside with several roles across various levels in organisms. Beyond its intracellular involvement in cellular metabolism, extracellular adenosine potently influences both physiological and pathological processes.
Jakub Šofranko +8 more
doaj +1 more source
CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability
Molecular Oncology, Volume 19, Issue 6, Page 1561-1564, June 2025.Micronuclei, formed during cell division in chromosomal instability settings, rupture and lead to the accumulation of immunogenic double‐stranded RNA in the cytoplasm, activating MAVS‐dependent interferon signaling and innate antitumor immunity.
Aglaia Skolariki +2 more
wiley +1 more source
MicroorganismsLactic acid bacteria are considered an inexhaustible source of bioactive compounds; indeed, products from their metabolism are known to have immunomodulatory and anti-inflammatory activity.
Luca Spaggiari +9 more
doaj +1 more source
Synthetic RNA and DNA Duplexes. Premelting, Melting and Postmelting Transitions of Alternating Inosine-Cytosine Polynucleotides in Solution [PDF]
, 1978 Dinshaw J. Patel
openalex +1 more source
Akkermansia muciniphila Metabolite Inosine Inhibits Castration Resistance in Prostate Cancer
MicroorganismsProstate cancer (PCa) is initially sensitive to androgen deprivation therapy (ADT) but ultimately develops resistance and progresses to castration-resistant prostate cancer (CRPC) with a poor prognosis.
Yao Yu +8 more
doaj +1 more source
INOSINE MONOPHOSPHATE (IMP) AND HYPOXANTHINE FORMATION IN THREE SPECIES OF SHRIMP HELD ON ICE [PDF]
, 1971 Frederick E. Stone
openalex +1 more source
Advanced Science, Volume 12, Issue 21, June 5, 2025.The gut microbiome is a potential target for treating cardiovascular disease. It is found that prophylactic administration of Flavonifractor plautii or its metabolite desaminotyrosine (DAT) exerts pleiotropic cardioprotective effects via promoting cardiomyocyte survival and attenuating cardiac inflammation against myocardial ischemia/reperfusion (I/R ...
Heng Du +21 more
wiley +1 more source