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The Role of Inositol in Thyroid Physiology and in Subclinical Hypothyroidism Management

open access: yesFrontiers in Endocrinology, 2021
Myo-Inositol (MYO) is the most abundant stereoisomer of inositols’ family, cyclic polyols with 6 hydroxyl groups. Myo-Inositol has a relevant role in thyroid function and autoimmune diseases, as a precursor of phosphoinositides that takes part in the ...
Salvatore Benvenga   +7 more
doaj   +2 more sources

Treatment with Myo-Inositol Does Not Improve the Clinical Features in All PCOS Phenotypes

open access: yesBiomedicines, 2023
Background: The aim of the present study is to investigate the effects produced by a treatment with myo-Inositol (myo-Ins) in women presenting polycystic ovary syndrome (PCOS) of different phenotypes.
Vittorio Unfer   +5 more
doaj   +1 more source

Boswellia, inositol and betaine in the treatment of fibroadenoma: a case study [PDF]

open access: yesInternational Journal of Medical Device and Adjuvant Treatments, 2020
OBJECTIVE: Nowadays, no completely side effect-free therapeutic approach for mammary fibroadenomas exists, considering that the election therapy is based on antiestrogens, as well as on surgery for more severe cases.
N. Monti, V. Pasta, V. D’Orazi
doaj   +1 more source

New Insights into the Activities of D-Chiro-Inositol: A Narrative Review

open access: yesBiomedicines, 2021
D-chiro-inositol (DCI) is a natural compound detectable in cell membranes, which is highly conserved as a biological signaling molecule. In mammals, its function is primarily characterized in the intracellular transduction cascade of insulin.
Riccardo Gambioli   +5 more
doaj   +1 more source

Oxidative Stress and Male Fertility: Role of Antioxidants and Inositols

open access: yesAntioxidants, 2021
Infertility is defined as a couple’s inability to conceive after at least one year of regular unprotected intercourse. This condition has become a global health problem affecting approximately 187 million couples worldwide and about half of the cases are
Maria Nunzia De Luca   +4 more
doaj   +1 more source

A Markov-model simulation of IVF programs for PCOS patients indicates that coupling myo-Inositol with rFSH is cost-effective for the Italian Health System

open access: yesScientific Reports, 2023
Accumulating evidence suggests that oral supplementation with myo-Inositol (myo-Ins) is able to reduce the amount of gonadotropins and days of controlled ovarian hyperstimulation (COS) necessary to achieve adequate oocyte maturation in assisted ...
Ariel Beresniak   +7 more
doaj   +1 more source

Neurobiology and Applications of Inositol in Psychiatry: A Narrative Review

open access: yesCurrent Issues in Molecular Biology, 2023
Inositol is a natural sugar-like compound, commonly present in many plants and foods. It is involved in several biochemical pathways, most of them controlling vital cellular mechanisms, such as cell development, signaling and nuclear processes, metabolic
Carmen Concerto   +13 more
doaj   +1 more source

Myo-Inositol as a Key Supporter of Fertility and Physiological Gestation

open access: yesPharmaceuticals, 2021
Pregnancy is a complex process, featuring several necessary changes in women’s physiology. Most women undergo healthy pregnancies; even so, several women experience reduced fertility or pathologies related to the pregnancy. In the last years, researchers
Riccardo Gambioli   +4 more
doaj   +1 more source

ENDOMETRIOSIS-ASSOCIATED INFERTILITY: THE ROLE OF HORMONES AND ITS CORRECTION

open access: yesInternational Journal of Medicine and Medical Research, 2021
Background. Endometriosis-associated infertility (EAI) has a number of specific features, which are crucial in the choice of medical treatment. Objective.
I. I. Kulyk, S. V. Khmil
doaj   +1 more source

Inositol Pyrophosphate Pathways and Mechanisms: What Can We Learn from Plants?

open access: yesMolecules, 2020
The ability of an organism to maintain homeostasis in changing conditions is crucial for growth and survival. Eukaryotes have developed complex signaling pathways to adapt to a readily changing environment, including the inositol phosphate (InsP ...
Caitlin Cridland, Glenda Gillaspy
doaj   +1 more source

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