Results 211 to 220 of about 270,142 (371)

Xanomeline‐Trospium Chloride (Cobenfy): A New Era in Managing Schizophrenia—Comparative Effectiveness and Economic Challenges

open access: yesMedicine Advances, EarlyView.
Xanomeline‐trospium chloride (cobenfy) is a muscarinic agonist used to treat hallucinations and psychotic illnesses such as Alzheimer's and Schizophrenia. It has been constructed for patients who are unable to tolerate dopamine‐targeting therapies and a comparison is drawn against other similar drugs with variables like cost, mechanism of action ...
Jawairya Muhammad Hussain   +4 more
wiley   +1 more source

Changes in Liver Metabolome Induced by Pterostilbene and Resveratrol in a Rat Model of Liver Steatosis

open access: yesMolecular Nutrition &Food Research, EarlyView.
Resveratrol and pterostilbene reduced the steatotic status of animals fed a high‐fat, high‐sucrose diet, involving differential and specific mechanisms of action for each stilbene. Thus, changes in riboflavin metabolism, nicotinamide mononucleotide metabolism, or in the LysoPC(18:1)‐mediated effects contribute to the specific actions of pterostilbene ...
Alfredo Fernández‐Quintela   +5 more
wiley   +1 more source

THE SYNTHESIS OF myo-INOSITOL IN THE RAT

open access: hybrid, 1955
June W. Halliday, Laurens Anderson
openalex   +1 more source

gammaSTAR: A framework for the development of dynamic, real‐time capable MR sequences

open access: yesMagnetic Resonance in Medicine, EarlyView.
Abstract Purpose To present the real‐time capability and advanced MR sequence library of the MR sequence development framework gammaSTAR. Methods The presented platform consists of four different components: (1) a frontend for sequence development combined with a Python backend for sequence generation; (2) a Lua backend for the creation of hardware ...
Simon Konstandin   +2 more
wiley   +1 more source

Downregulation of forkhead box O1 (FOXO1) acetylation ameliorates cognitive dysfunction by inhibiting endoplasmic reticulum stress‐regulated neuronal apoptosis in APP/PS1 transgenic mice

open access: yesNeuroprotection, EarlyView.
Downregulation of the expression of silent information regulator sirtuin 1 (SIRT1) exacerbates neuronal degeneration and loss by activating forkhead box O1 (FOXO1) acetylation and promoting endoplasmic reticulum stress (ERSA)‐mediated apoptosis in aging.
Nan Zhang   +20 more
wiley   +1 more source

Home - About - Disclaimer - Privacy