Results 221 to 230 of about 162,796 (303)

Impact of Adjunctive Myo-Inositol and Magnesium Therapy on Paediatric Overactive Bladder: A Retrospective Analysis. [PDF]

Children (Basel)
Colletti A, Favro M, Sangiorgio L.
europepmc   +1 more source

Proteome-wide quantification of inositol pyrophosphate-protein interactions. [PDF]

Nat Commun
Richter A, Isern JA, Ruwolt M, Lampe S, Majumdar A, Liu F, Furkert D, Fiedler D.   +7 more
europepmc   +1 more source

A 58‐year‐old woman experiencing occasional dizziness, impaired awareness, and deep feeling of fear

Brain Pathology, EarlyView.
Alessandro Selvaggini, Sabrina Rossi, Marco Brollo, Sabina Barresi, Laurino Licia, Lorenzo Nicolè   +5 more
wiley   +1 more source

CKAP4 Regulates ERS‐Induced Apoptosis in Osteoclasts Through FOXO3 in Periodontitis

Cell Proliferation, EarlyView.
CKAP4 promotes the transcription of PERK via FOXO3 in OCs, thereby facilitating ER stress‐induced apoptosis. In periodontitis, the reduction of CKAP4 in OCs leads to decreased OC apoptosis, which exacerbates alveolar bone resorption. ABSTRACT Periodontitis is a prevalent oral disease characterised by chronic inflammation and irreversible alveolar bone ...
Jiayu Cheng, Dihao Tao, Wenzhe Wang, Huiyu Wang, Hanzhe Wang, Yufan Liang, Jia Guo, Wenhao Liu, Yiming Wang, Jianhua Yang, Xiaoning He, Ce Shan, Bei Li   +12 more
wiley   +1 more source

Expression of Concern: Signaling Networks Associated with AKT Activation in Non-Small Cell Lung Cancer (NSCLC): New Insights on the Role of Phosphatydil-Inositol-3 kinase. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib, Francisco Emilio Fierro, Maria Ortega Abad, Ricardo Correa   +3 more
wiley   +1 more source

Sodium-myo-inositol cotransporter-1, SMIT1, promotes cardiac hypertrophy and fibrosis induced by pressure overload in mice. [PDF]

Cardiovasc Res
Marino A, Cumps J, Guilbert L, Geiser A, Baufays C, Ginion A, Ferté L, Battault S, De Matos F, Ambroise J, Zuurbier CJ, Lezoualc'h F, Pestiaux C, Pyka G, Kerckhofs G, Roderick HL, Bertrand L, Horman S, Beauloye C.   +18 more
europepmc   +1 more source

ER proteostasis meets mitochondrial function: contact sites as hubs of communication and therapeutic targets

The FEBS Journal, EarlyView.
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna, Alessandro Cherubini, Ersilia Varone, Serena Germani, Alice Marrazza, Ester Zito   +5 more
wiley   +1 more source

Proteostasis of organelles in aging and disease

The FEBS Journal, EarlyView.
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi, Cansu Doğan, Dunja Petrović, Gülce Perçin, Seda Koyuncu, David Vilchez   +5 more
wiley   +1 more source

NMR metabolomics assessment of neural commitment of human dental pulp-derived stem cells. [PDF]

Front Mol Biosci
Chirico M, Pisanu ME, Mari E, Manganelli V, Pulcini F, Lancia L, Di Benedetto R, Delle Monache S, Iorio E, Mattei V.   +9 more
europepmc   +1 more source