Inositol - why should it be in the spotlight for women in a reproductive age?
Journal of Education, Health and Sport, 2023 Introduction and purpose: Inositol exists in the form of nine isomers, two of which are dominant - myo-inositol (MI) and D-chiro-inositol (DCI). It is a naturally occuring sugar involved in many biological pathways. Due to its insulin-sensitizing, anti-
Sebastian Tomaszuk +2 more
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The Potential Use of Ebselen in Treatment-Resistant Depression
Pharmaceuticals, 2022 Ebselen is an organoselenium compound developed as an antioxidant and subsequently shown to be a glutathione peroxidase (GPx) mimetic. Ebselen shows some efficacy in post-stroke neuroprotection and is currently in trial for the treatment and prevention ...
Fitri Fareez Ramli +2 more
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A role for Gle1, a regulator of DEAD-box RNA helicases, at centrosomes and basal bodies. [PDF]
, 2017 Control of organellar assembly and function is critical to eukaryotic homeostasis and survival. Gle1 is a highly conserved regulator of RNA-dependent DEAD-box ATPase proteins, with critical roles in both mRNA export and translation.
Akef, Abdalla +2 more
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An In Vitro Enzyme System for the Production of myo -Inositol from Starch [PDF]
Applied and Environmental Microbiology, 2017 Tomoko Fujisawa +2 more
openalex +2 more sources
Systematic analysis of the biological roles and pharmacological properties of D-chiro-inositol [PDF]
Гинекология, 2020 D-chiroinositol (DCI) is one of the 9 inositol isomers that forms inositol phosphoglycans, which are mediators of the action of insulin. The metabolism of DCI and myo-inositol (MI) is impaired against the background of insulin resistance, including the ...
Olga A. Gromova +4 more
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Cellular IP6 Levels Limit HIV Production while Viruses that Cannot Efficiently Package IP6 Are Attenuated for Infection and Replication [PDF]
, 2019 Summary: HIV-1 hijacks host proteins to promote infection. Here we show that HIV is also dependent upon the host metabolite inositol hexakisphosphate (IP6) for viral production and primary cell replication.
Böcking, Till +10 more
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Nature Communications, 2020 Inositol polyphosphates are vital metabolic and secondary messengers, involved in diverse cellular functions. Therefore, tight regulation of inositol polyphosphate metabolism is essential for proper cell physiology.
E. Ucuncu +30 more
semanticscholar +1 more source
Molecules, 2020 (1) Background: Myoinositol (MI) and D-chiro-inositol (DCI) are involved in a number of biochemical pathways within oocytes having a role in oocyte maturation, fertilization, implantation, and post-implantation development. Both inositols have a role in insulin signaling and hormonal synthesis in the ovaries.
Zdravko Kamenov, Antoaneta Gateva
openaire +3 more sources
Myo-Inositol and Its Derivatives: Their Emerging Role in the Treatment of Human Diseases
Frontiers in Pharmacology, 2019 Myo-inositol has been established as an important growth-promoting factor of mammalian cells and animals. The role of myo-inositol as a lipotropic factor has been proven, in addition to its involvement as co-factors of enzymes and as messenger molecules ...
D. R. Chhetri
semanticscholar +1 more source
Tipping the scales:Lessons from simple model systems on inositol imbalance in neurological disorders [PDF]
, 2017 Inositol and inositol-containing compounds have signalling and regulatory roles in many cellular processes, suggesting that inositol imbalance may lead to wide-ranging changes in cellular functions.
Abe +140 more
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