Results 41 to 50 of about 58,268 (235)
Mitochondrial respiration and Ca2+ waves are linked during fertilization and meiosis completion [PDF]
Fertilization increases both cytosolic Ca(2+) concentration and oxygen consumption in the egg but the relationship between these two phenomena remains largely obscure.
Smith, Peter J. +9 more
core +1 more source
Inositol 1,4,5-trisphosphate receptor 1 is essential to spinocerebellar ataxia modeling
A suite of models was developed to study the role of inositol 1,4,5-trisphosphate receptor 1 (IP3R1) in spinocerebellar ataxias (SCAs). Several SCAs are linked to reduced abundance of IP3R1 or to supranormal sensitivity of the receptor to activation by ...
Sherry-Ann eBrown, Leslie M. Loew
doaj +1 more source
Inositol 1,4,5-trisphosphate receptor expression in odontoblast cells [PDF]
The cellular distribution of inositol 1,4,5-trisphosphate receptors was examined in rodent maxillary incisor teeth. In situ hybridization studies with a transmembrane probe of type I inositol 1,4,5-trisphosphate receptor indicated that this receptor ...
Steven E Arnold +13 more
core +1 more source
Inositol 1,4,5-Trisphosphate and Calcium Regulate the Calcium Channel Function of the Hepatic Inositol 1,4,5-Trisphosphate Receptor [PDF]
The regulation of the inositol 1,4,5-trisphosphate (IP3) receptor in liver was analyzed using a novel superfusion method. Hepatic microsomes were loaded with 45Ca2+, and superfused at high flow rates to provide precise control over IP3 and Ca2+ concentrations ([Ca2+]) and to isolate 45Ca2+ release from reuptake.
J F, Dufour, I M, Arias, T J, Turner
openaire +2 more sources
An anti-leptin receptor polyclonal antibody (receptor antibody), as well as leptin, stimulated the release of free fatty acids from isolated mouse fat pads in a time-dependent manner.
Natsuyo Kawaji +4 more
doaj +1 more source
http://ukrbiochemjournal.org/wp-content/uploads/2015/11/Kosterin_6_13.pdf [PDF]
2- and 3-dimensional confocal imaging of Fluo-4 loaded ureteric microvesells in situ allowed us to demonstrate distinct morphology, Ca2+ signalling and contractility in myocytes of arcade arterioles and pericytes of arcade venules.
T. Burdyga, L. Borysova
doaj +1 more source
Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by analogues of IP3. [PDF]
Most animal cells express mixtures of the three subtypes of inositol 1,4,5-trisphosphate receptor (IP(3)R) encoded by vertebrate genomes. Activation of each subtype by different agonists has not hitherto been examined in cells expressing defined ...
Huma Saleem +5 more
doaj +1 more source
Summary: This protocol outlines steps to visualize and detect Ca2+ puffs following photo-liberation of caged inositol-1,4,5-trisphosphate (IP3) from HEK-293 cells expressing only the native IP3R type 1 receptor using total internal reflection ...
Vikas Arige +4 more
doaj +1 more source
TMEM16A Ca2+-activated Cl− channels are expressed in pancreatic acinar cells and participate in inflammation-associated diseases. Whether TMEM16A contributes to the pathogenesis of acute pancreatitis (AP) remains unknown.
Qinghua Wang +13 more
doaj +1 more source
Cardiac inositol 1,4,5-trisphosphate receptors
Calcium is a second messenger that regulates almost all cellular functions. In cardiomyocytes, calcium plays an integral role in many functions including muscle contraction, gene expression, and cell death. Inositol 1,4,5-trisphosphate receptors (IP3Rs) are a family of calcium channels that are ubiquitously expressed in all tissues. In the heart, IP3Rs
M Iveth, Garcia, Darren, Boehning
openaire +2 more sources

