Results 21 to 30 of about 70,433 (242)

Regulated inositol synthesis is critical for balanced metabolism and development in Drosophila melanogaster

open access: yesBiology Open, 2021
Myo-inositol is a precursor of the membrane phospholipid, phosphatidylinositol (PI). It is involved in many essential cellular processes including signal transduction, energy metabolism, endoplasmic reticulum stress, and osmoregulation.
Maria J. Rivera   +4 more
doaj   +1 more source

Metabolic Consequences of Polyphosphate Synthesis and Imminent Phosphate Limitation

open access: yesmBio, 2023
Cells stabilize intracellular inorganic phosphate (Pi) to compromise between large biosynthetic needs and detrimental bioenergetic effects of Pi.
Geun-Don Kim   +3 more
doaj   +1 more source

Degradation of phytate by the 6-phytase from Hafnia alvei: a combined structural and solution study. [PDF]

open access: yesPLoS ONE, 2013
Phytases hydrolyse phytate (myo-inositol hexakisphosphate), the principal form of phosphate stored in plant seeds to produce phosphate and lower phosphorylated myo-inositols.
Antonio Ariza   +12 more
doaj   +1 more source

Inositol phosphates in the environment [PDF]

open access: yesPhilosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2002
The inositol phosphates are a group of organic phosphorus compounds found widely in the natural environment, but that represent the greatest gap in our understanding of the global phosphorus cycle. They exist as inositols in various states of phosphorylation (bound to between one and six phosphate groups) and isomeric forms (e.g.
Turner, B. L.   +3 more
openaire   +2 more sources

Inositols in Insulin Signaling and Glucose Metabolism

open access: yesInternational Journal of Endocrinology, 2018
In the past decades, both the importance of inositol for human health and the complex interaction between glucose and inositol have been the subject of increasing consideration. Glucose has been shown to interfere with cellular transmembrane transport of
Arturo Bevilacqua, Mariano Bizzarri
doaj   +1 more source

A Gas Chromatography-Mass Spectrometry-Based Two Stage Assay for Measurement of in vitro myo-Inositol 3-phosphate Synthase (INO1) Activity

open access: yesBio-Protocol, 2015
This method describes an in vitro assay for measuring INO1 enzyme activity (the conversion of glucose 6-phosphate to myo-inositol 3-phosphate) in cell-free extracts. The method was first described for Plasmodium falciparum cells in MacRae et al.
James MacRae, Malcolm McConville
doaj   +1 more source

Countercurrent distribution of inositol lipids of plant seeds

open access: yesJournal of Lipid Research, 1969
The inositol lipids of plant seeds consist of phosphatidyl inositol, the phytoglycolipids, and a previously uncharacterized ceramide-phosphate-polysaccharide. These three species have been separated from each other and from the common glycerophosphatides
H.E. Carter, A. Kisic
doaj   +1 more source

A Role for Inositol Pyrophosphates in the Metabolic Adaptations to Low Phosphate in Arabidopsis

open access: yesMetabolites, 2021
Phosphate is a major plant macronutrient and low phosphate availability severely limits global crop productivity. In Arabidopsis, a key regulator of the transcriptional response to low phosphate, phosphate starvation response 1 (PHR1), is modulated by a ...
Eric S. Land   +7 more
doaj   +1 more source

The Role of Inositol in Thyroid Physiology and in Subclinical Hypothyroidism Management

open access: yesFrontiers in Endocrinology, 2021
Myo-Inositol (MYO) is the most abundant stereoisomer of inositols’ family, cyclic polyols with 6 hydroxyl groups. Myo-Inositol has a relevant role in thyroid function and autoimmune diseases, as a precursor of phosphoinositides that takes part in the ...
Salvatore Benvenga   +7 more
doaj   +1 more source

Inositol monophosphate phosphatase genes of Mycobacterium tuberculosis

open access: yesBMC Microbiology, 2010
Background Mycobacteria use inositol in phosphatidylinositol, for anchoring lipoarabinomannan (LAM), lipomannan (LM) and phosphatidylinosotol mannosides (PIMs) in the cell envelope, and for the production of mycothiol, which maintains the redox balance ...
Parish Tanya   +6 more
doaj   +1 more source

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