Results 21 to 30 of about 761,638 (295)
Molecules, 2021 IP6K and PPIP5K are two kinases involved in the synthesis of inositol pyrophosphates. Synthetic analogs or mimics are necessary to understand the substrate specificity of these enzymes and to find molecules that can alter inositol pyrophosphate synthesis.
Raja Mohanrao +5 more
doaj +1 more source
Characterization of three vasopressin receptor 2 variants: an apparent polymorphism (V266A) and two loss-of-function mutations (R181C and M311V). [PDF]
, 2013 Arginine vasopressin (AVP) is released from the posterior pituitary and controls water homeostasis. AVP binding to vasopressin V2 receptors (V2Rs) located on kidney collecting duct epithelial cells triggers activation of Gs proteins, leading to increased
Armstrong, Stephen P +4 more
core +6 more sources
MCK1 is a novel regulator of myo-inositol phosphate synthase (MIPS) that is required for inhibition of inositol synthesis by the mood stabilizer valproate. [PDF]
PLoS ONE, 2017 Myo-inositol, the precursor of all inositol compounds, is essential for the viability of eukaryotes. Identifying the factors that regulate inositol homeostasis is of obvious importance to understanding cell function and the pathologies underlying ...
Wenxi Yu +4 more
doaj +1 more source
Inositol Signaling in the Basidiomycete Fungus Schizophyllum commune
Journal of Fungi, 2021 Intracellular signaling is conserved in eukaryotes to allow for response to extracellular signals and to regulate development and cellular functions. In fungi, inositol phosphate signaling has been shown to be involved in growth, sexual reproduction, and
Reyna Murry +6 more
doaj +1 more source
Myo- inositol and its metabolites in abiotic stress tolerance in plants [PDF]
Journal of Stress Physiology & Biochemistry, 2022 Myo-inositol (MI) is a sugar-alcohol produced by most plants and animals. 1L-myo-Inositol- 1-phosphate synthase (MIPS) is the rate limiting enzyme that catalyzes the conversion of D-glucose 6- phosphate to 1L-myo-inositol-1-phosphate, the first step in ...
Raksha Mukhia, Dhani Raj Chhetri
doaj
Poultry Science, 2023 This study investigated the effects of phytase and monocalcium phosphate supplementation on the dephosphorylation of phytic acid [myo-inositol 1,2,3,4,5,6-hexakis (dihydrogen phosphate); InsP6] in cecectomized laying hens using total excreta collection ...
W. Siegert +3 more
doaj +1 more source
Biochemical Journal, 2020 Inositol polyphosphates are ubiquitous molecular signals in metazoans, as are their pyrophosphorylated derivatives that bear a so-called ‘high-energy’ phosphoanhydride bond.
H. Whitfield +6 more
semanticscholar +1 more source
Phytase dose-dependent response of kidney inositol phosphate levels in poultry.
PLoS ONE, 2022 Phytases, enzymes that degrade phytate present in feedstuffs, are widely added to the diets of monogastric animals. Many studies have correlated phytase addition with improved animal productivity and a subset of these have sought to correlate animal ...
Colleen Sprigg +5 more
doaj +2 more sources
Journal of Biological Chemistry, 2020 Solute carrier family 20 member 2 (SLC20A2) and xenotropic and polytropic retrovirus receptor 1 (XPR1) are transporters with phosphate uptake and efflux functions, respectively.
Uriel López-Sánchez +9 more
semanticscholar +1 more source
Phosphatidylinositol (4,5)-bisphosphate turnover by INP51 regulates the cell wall integrity pathway in "Saccharomyces cerevisiae" [PDF]
, 2004 Signal transduction pathways are important for the cell to transduce external or internal stimuli where second messengers play an important role as mediators of the stimuli. One important group of second messengers are the phosphoinositide family present
Morales-Johansson, Helena
core +2 more sources