Results 31 to 40 of about 191 (92)

CRISPR-Mediated Transcriptional Activation of Squalene Synthase to Increase the Biosynthesis of Anticancer Metabolite Inotodiol in Inonotus Obliquus: A Research Protocol

Undergraduate Research in Natural and Clinical Science and Technology Journal
Chaga (Inonotus obliquus) is a parasitic fungus of birch trees used in the traditional medicine of Russia, China, and other Eurasian countries. The secondary metabolites produced by I. obliquus are known to possess anticancer, anti-inflammatory, antiviral, antioxidant, and hypoglycemic activity, while posing no known adverse effects.
Adrian G. Jones, Dylan T. Remington
openaire   +1 more source

Protective Effects of Lanostane Triterpenoids from Chaga Mushroom in Human Keratinocytes, HaCaT Cells, against Inflammatory and Oxidative Stresses. [PDF]

Int J Mol Sci, 2023
Park J, Nguyen TMN, Park HA, Nguyen MTT, Lee NY, Ban SY, Park KB, Lee CK, Kim J, Park JT.   +9 more
europepmc   +1 more source

Inotodiol Ameliorates Oxidative Stress and Apoptosis by Regulating PI3K/Akt/GSK-3β Signaling Pathways in Diabetic Nephropathy

Abstract Diabetic nephropathy (DN), a kind of microvascular complication, is a primary cause of end-stage kidney disease worldwide. However, therapeutic drugs for DN treatment are still in lack. Inotodiol (INO), a kind of lanostane triterpenoid isolated from INO that has various biological activities.
Lingling Tian, Qi Duan, Rongshan Li, Yafeng Li   +3 more
openaire   +1 more source

Research Progress on Application of Inonotus obliquus in Diabetic Kidney Disease. [PDF]

J Inflamm Res, 2023
Wang S, Wang R, Li R, Li Y.
europepmc   +1 more source

Special Issue Editorial: Isolation and Analysis of Characteristic Compounds from Herbal and Plant Extracts. [PDF]

Plants (Basel), 2021
Kang JS, Yadav NS.
europepmc   +1 more source

Countering Triple Negative Breast Cancer via Impeding Wnt/β-Catenin Signaling, a Phytotherapeutic Approach. [PDF]

Plants (Basel), 2022
Arzi L, Mollaei H, Hoshyar R.
europepmc   +1 more source

Genome sequencing of Inonotus obliquus reveals insights into candidate genes involved in secondary metabolite biosynthesis. [PDF]

BMC Genomics, 2022
Duan Y, Han H, Qi J, Gao JM, Xu Z, Wang P, Zhang J, Liu C.   +7 more
europepmc   +1 more source

INO10, a Chaga Mushroom Extract, Alleviates Alzheimer's Disease-Related Pathology and Cognitive Deficits in 3xTg-AD Mice. [PDF]

Int J Mol Sci
Ban S, Do TT, Pyo JW, Moon M, Park JT.
europepmc   +1 more source

The Inclusion of Dietary and Medicinal Mushrooms into Translational Oncology: Pros and Cons at the Molecular Level. [PDF]

Int J Mol Sci
Kirdeeva Y, Fefilova E, Karpova N, Parfenyev S, Daks A, Nazarov A, Semenov O, Anh NTV, Loc VT, Cuong NM, Shuvalov O.   +10 more
europepmc   +1 more source

Comparative Study of Chaga (<i>Inonotus obliquus</i>) Dietary Supplements Using Complementary Analytical Techniques. [PDF]

Int J Mol Sci
Windsor C, Kreynes AE, Chilton JS, Chioffi WA, Krishnamurthy A, Ishii M.   +5 more
europepmc   +1 more source