Results 91 to 100 of about 16,142,007 (311)

Philosophical Inquiry to Advance Cosmopolitan Engagement

open access: yes, 2012
Il progetto intende promuovere lo sviluppo di attitudini, competenze, stili di pensiero caratterizzati dalla capacità di essere riflessivamente consapevoli delle proprie radici e della propria identità e allo stesso tempo di aprirsi al nuovo e al ...
Camhy D.   +3 more
core  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The Interrogative Model of Inquiry and Inquiry Learning

open access: yes, 2016
Hakkarainen and Sintonen (2002) praise the descriptive adequacy of Hintikka's Interrogative Model of Inquiry (imi) to describe children's practices in an inquiry-based learning context.
Gulz, Agneta,   +3 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

A Systematic Review on Assessment in Inquiry-Based Science Education

open access: yesInternational Journal of Research in STEM Education
Despite increased advocacy for the use of inquiry-based learning as part of innovative science teaching in various countries over the last decade, research on the assessment of inquiry-based instruction in science education has lagged, with few ...
Ayodele Ogegbo   +3 more
doaj   +1 more source

THE UTILIZATION OF INQUIRY-BASED SCIENCE INSTRUCTION IN CONNECTICUT

open access: yes, 2017
The purpose of this study was to explore the perspectives of practitioners of inquiry-based instruction from 35 Connecticut school districts. The source of the participants, Connecticut State Science Assessment Advisory Committee members, and their ...
Bozzuto, David
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Effects of just-in-time inquiry prompts and principle-based self-explanation guidance on learning and use of domain texts in simulation-based inquiry learning

open access: yesFrontiers in Education
Although scientific inquiry with simulations may enhance learning, learners often face challenges creating high demand for self-regulation due to an abundance of information in simulations and supplementary instructional texts.
Mari Fukuda   +3 more
doaj   +1 more source

UNDERSTANDING TEACHER USE OF INQUIRY: INVESTIGATING CATALYSTS AND BARRIERS

open access: yes, 2015
The purpose of this qualitative, multiple-case study was to investigate the catalysts and barriers related to implementing inquiry-based instruction in elementary school from the perspective of third, fourth, and fifth grade teachers.
Guertin, Susan
core  

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