Results 61 to 70 of about 59,060 (257)

Training of Development of Inquiry-Based and Project-Based Chemistry Learning Design for Chemistry & Science Teachers

J-PEK (Jurnal Pembelajaran Kimia), 2023
Abstrak – Nowadays, the demands of curriculum are increasing in achieving better standards of learning process. The low ability of chemistry and science teachers in developing inquiry-based and project-based learning designs is a problem that must be ...
Oktavia Sulistina, Hayuni Retno Widarti, Habiddin Habiddin, Herunata Herunata, Yahmin Yahmin, Samudra Mutiara Hasanah, Dhea Fairuza Zahirah   +6 more
doaj  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Inquiry-Based Learning in Design [PDF]

, 2019
The University of Applied Sciences FH Potsdam is known for its wide-ranging design education: Product and communications designers have been trained here since 1992, interface designers since 2003. In order to highlight the potentials as well as the difficulties and limitations of inquiry-based learning in the discipline of design, several design ...
Beyrow, Matthias, Godau, Marion, Heidmann, Frank, Langer, Constanze, Wettach, Reto, Mieg, Harald A.   +5 more
openaire   +2 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Inquiry Based Learning and Its Effectiveness

International Journal of Assessment Tools in Education, 2016
The aim of this study is to investigate the effectiveness of the inquiry based learning on the skills of the prospective teachers for the laboratory applications I course activities related to the developed chemistry experiments using semi-experimental ...
Sevilay Karamustafaoğlu, Ayşegül Celep Havuz   +1 more
doaj   +1 more source

THE EFFECTIVENESS COMPARISON BETWEEN INQUIRY AND PROBLEM BASED LEARNING TOWARDS GEOGRAPHY LEARNING OUTCOMES

Geosfera Indonesia, 2019
This study aims to determine the differences of learning outcomes between students that were performed using inquiry and student who were applied using problem based learning in classes of X SMA 2 Plakat Tinggi.
Upang Septa Putra, Muhsinatun Siasah Masruri   +1 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Inquiry-Based Learning in History [PDF]

, 2019
The goal of the following article is to develop the prospects for the concept of inquiry-based learning in the subject of history. At the start of the article, the current state of the research will be outlined and a separate understanding of the underlying term will be discussed.
Andreas Bihrer, Stephan Bruhn, Fiona Fritz   +2 more
openaire   +1 more source