Results 51 to 60 of about 868,028 (301)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

The Development of Science Process Skills and Content Knowledge with Inquiry Boxes in Early Childhood Education

open access: yesCenter for Educational Policy Studies Journal
This paper aims to investigate the systematic use of an inquiry-based learning approach in science by using inquiry boxes for preschool children. We prepared four thematic inquiry boxes for the areas of magnetism and buoyancy, separation of substances ...
Nika Golob, Vanja Ungar
doaj   +1 more source

Written evidence to the House of Commons Business and Skills Committee (ed) Local enterprise partnerships and the Regional Growth Fund [PDF]

open access: yes, 2012
The Business, Innovation and Skills Committee announced an inquiry looking into the Local Enterprise Partnerships and the Regional Growth Fund. In particular, the Committee examined how the proposed new structures would work, alongside issues such as ...
Bentley, G   +3 more
core  

Influence of training in inquiry-based methods on in-service science teachers’ reasoning skills

open access: yesChemistry Teacher International, 2019
Reasoning skills can be described as abilities to use scientific knowledge to identify and solve problems, and to formulate conclusions based on empirical observations.
Bernard Paweł, Dudek-Różycki Karol
doaj   +1 more source

The Promise of Faculty Inquiry for Teaching and Learning Basic Skills [PDF]

open access: yes, 2008
Shares insights from the Strengthening Pre-collegiate Education in Community Colleges project on how teachers' systematic and collaborative analyses of new approaches and practices foster innovation and improvement in basic English and math ...
Mary Taylor Huber
core  

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Improving The Mathematic Critical And Creative Thinking Skills In Grade 10th SMA Negeri 1 Kasihan Bantul On Mathematics Learning Through Problem-Based Learning [PDF]

open access: yes, 2011
This research aims to describe: (1) implementation of the PBL that improve the mathematic critical and creative thinking skills and (2) improvement the mathematic critical and creative thinking skills of students with PBL.
Endang Listyani, M.S., Nurina, Happy
core  

The Development of Inquiry Science Worksheet to Facilitate the Process Skills [PDF]

open access: yes, 2018
This research aimed for developing Inquiry Worksheet to facilitate the process skill. Inquiry Worksheet gave the opportunity for student to make good observations in giving hypothesis, designing the experiment, collecting, analyzing, and inferring the ...
Servitri, M. O. (Margaretha)   +1 more
core  

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