Results 81 to 90 of about 886,102 (271)

Adverse immunostimulation in early phase clinical trials: Key findings and recommendations based on the investigator's clinical experience

British Journal of Clinical Pharmacology, EarlyView.
Problem setting The emergence of therapeutic proteins has coincided with an increase of acute adverse immunostimulation (AIS). AIS has occured in clinical trials despite compliance with regulatory guidelines on preclinical evaluation and its incidence is anticipated to increase even further.
Juliette A. van den Noort, Marella C. E. van Ruissen, Lisanne C. A. Smidt, Naomi B. Klarenbeek, Philip H. K. Kremer, Manon A. A. Jansen, Jacobus Burggraaf, Joop M. A. van Gerven, Matthijs Moerland   +8 more
wiley   +1 more source

Educational philosophising in the Everyday: UK immigrant mothers navigating identity and praxis during COVID‐19

British Educational Research Journal, EarlyView.
Abstract Debates surrounding motherhood have long centred on women's roles as carers. Although motherhood is now more widely recognised within feminist scholarship, it often remains conceptually separate from identities associated with formal educational discourse.
Lavinia Kamphausen, Aliya Khalid, Nadia Uddin‐Talukder, Uzma Dayan   +3 more
wiley   +1 more source

Widening participation and the changing risks of higher education: Working‐class women's pathways via access courses across two decades

British Educational Research Journal, EarlyView.
Abstract Widening participation (WP) in higher education (HE) remains a central concern within UK educational and social policy. It seeks to address the underrepresentation of specific social groups by tailoring university access to their distinct needs.
Sarah McLaughlin, Richard Waller
wiley   +1 more source

Research reports : 50th Annual Northwest Insect Management Conference

Proceedings of the 50th Annual Northwest Insect Management Conference, held January 7-8, 1991 at the Imperial Hotel in Portland ...
Northwest Insect Management Conference
core   +3 more sources

Insect-pathogen crosstalk and the cellular-molecular mechanisms of insect immunity: uncovering the underlying signaling pathways and immune regulatory function of non-coding RNAs. [PDF]

Front Immunol, 2023
Mahanta DK, Bhoi TK, Komal J, Samal I, Nikhil RM, Paschapur AU, Singh G, Kumar PVD, Desai HR, Ahmad MA, Singh PP, Majhi PK, Mukherjee U, Singh P, Saini V, Shahanaz, Srinivasa N, Yele Y.   +17 more
europepmc   +1 more source

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

Biotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady, Nicholas Donohue, Alexandra Bogdanovic, Sharon Davin, Brian Glennon, Niall Barron, C. Mark Smales   +6 more
wiley   +1 more source

Current insights into insect immune memory

eLife
Traditionally, insects have been thought to be entirely dependent on their innate immune system, which has little capacity for the acquisition of experience from previous infections.
Gabriela Krejčová, Adam Bajgar
doaj   +1 more source

Structure prediction of honey bee vitellogenin: a multi-domain protein important for insect immunity. [PDF]

FEBS Open Bio, 2022
Leipart V, Montserrat-Canals M, Cunha ES, Luecke H, Herrero-Galán E, Halskau Ø, Amdam GV.   +6 more
europepmc   +1 more source

Ferritin as a Nanoparticle Scaffold for Plant‐Produced Next‐Generation Subunit Vaccines

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Protein nanoparticles offer an innovative approach to next‐generation subunit vaccine development by displaying antigenic sequences on the nanoparticle surface. Compared to traditional subunit vaccines, protein nanoparticle vaccines often show improved interaction with the immune system due to their particulate size and repetitive epitope ...
Jordan T. VanderBurgt, Richard Strasser, Christopher P. Garnham, Rima Menassa   +3 more
wiley   +1 more source

Single-cell transcriptional landscapes of Aedes aegypti midgut and fat body after a bloodmeal

Cell Genomics
Summary: Aedes aegypti mosquitoes transmit arboviruses that pose a growing global health threat. After a bloodmeal, mosquitoes experience complex physiological changes orchestrated by the midgut and fat body, beginning with digestion and culminating in ...
Thomas Vial, Hélène Lopez-Maestre, Elodie Couderc, Silvain Pinaud, Virginia Howick, Jewelna Akorli, Mara Lawniczak, Guillaume Marti, Sarah Hélène Merkling   +8 more
doaj   +1 more source