Results 211 to 220 of about 6,007,261 (298)

Enclosures with flexible structures stimulate species-typical locomotion, but not locomotion quantity, in zoo-housed Bornean orangutans (<i>Pongo pygmaeus</i>). [PDF]

Anim Welf
Geijtenbeek JW, van den Berg L, Roth T.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

African carnivore gut bacterial diversity and composition are associated with sample condition but not storage technique. [PDF]

Anim Microbiome
Peirson LE, McKenney EA, Patterson JR, Beasley JC, Périquet-Pearce S, Cloete C, Melton MH, PetersonWood B, Portas R, Aschenborn O, Lafferty DJR.   +10 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Fiduciary Loyalty, Inside and Out [PDF]

, 2018
Galoob, Stephen R., Leib, Ethan J.
core   +1 more source

Metabolic Myokines and Adipokines in the Follicular Microenvironment: Implications for Oocyte Competence and IVF Outcomes. [PDF]

Int J Mol Sci
Voros C, Chatzinikolaou F, Papadimas G, Papapanagiotou I, Karpouzos A, Koulakmanidis AM, Athanasiou D, Bananis K, Athanasiou A, Athanasiou A, Tsimpoukelis C, Daskalaki MA, Trakateli C, Koranteng NK, Thomakos N, Antsaklis P, Loutradis D, Daskalakis G.   +17 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Inside Information Fall 2018 [PDF]

, 2018
McCaffrey, Ariela
core   +2 more sources

Computation of topological relations with 3-SRM. [PDF]

Sci Rep
Totad NP, Sajjanshettar GM, Aithal PK.
europepmc   +1 more source