Results 1 to 10 of about 28,218 (161)

Garcinol loaded vitamin E TPGS emulsified PLGA nanoparticles: preparation, physicochemical characterization, in vitro and in vivo studies [PDF]

Scientific Reports, 2017
Garcinol (GAR) is a naturally occurring polyisoprenylated phenolic compound. It has been recently investigated for its biological activities such as antioxidant, anti-inflammatory, anti ulcer, and antiproliferative effect on a wide range of human cancer ...
Raghuvir H. Gaonkar, Soumya Ganguly, Saikat Dewanjee, Samarendu Sinha, Amit Gupta, Shantanu Ganguly, Dipankar Chattopadhyay, Mita Chatterjee Debnath   +7 more
doaj   +2 more sources

Effect of Grass Carp Scale Collagen Peptide FTGML on cAMP-PI3K/Akt and MAPK Signaling Pathways in B16F10 Melanoma Cells and Correlation between Anti-Melanin and Antioxidant Properties

Foods, 2022
Peptide Phe-Thr-Gly-Met-Leu (FTGML) is a bioactive oligopeptide with tyrosinase inhibitory activity derived from gelatin hydrolysate of grass carp scales.
Xiaomei Sha, Lu Zhang, Zong-Cai Tu
exaly   +3 more sources

The inhibitory effects of vanillin on the growth of melanoma by reducing nuclear factor-κB activation

Advanced Biomedical Research, 2022
Background: Melanoma is skin cancer, and the treatments are not efficient enough. Therefore, finding new drugs seems to be an essential need. Vanillin, which is extracted from vanilla seed, has anti-cancer effects by reducing nuclear factor-κB (NF).
Marjan Pourhadi, Ahmad Ghasemi, Reza Abediny, Shaghayegh Haghjooy Javanmard, Golnaz Vaseghi   +4 more
doaj   +1 more source

Tanshinone IIA, a melanogenic ingredient basis of Salvia miltiorrhiza Bunge

Dermatologica Sinica, 2021
Background: The roots of Salvia miltiorrhiza Bunge (Lamiaceae) have been often used to treat vitiligo in clinical for many years. However, the main ingredient basis of efficacy has not been known.
Zhaojing Wang, Huihao Tang, Lili Yang, Yiming Li, Huali Wu   +4 more
doaj   +1 more source

Inhibitory Effects of Cycloheterophyllin on Melanin Synthesis

Molecules, 2021
This study was performed to clarify the inhibitory effects of cycloheterophyllin on melanin synthesis. In order to elucidate the inhibitory effects of cycloheterophyllin on the B16F10 cell line, cell viability, messenger ribonucleic acid (mRNA ...
Joong-Hyun Shim
doaj   +1 more source

Curcuma longa extract inhibits the activity of mushroom tyrosinase and the growth of murine skin cancer B16F10 cells [PDF]

Journal of HerbMed Pharmacology, 2023
Introduction: Tyrosinase is considered an important target of melanin biosynthesis inhibitors. Curcuma longa L. has been used in the Javanese traditional whitening cosmetics. This work aimed to explore the effect of C.
Deni Firmansyah, Sri Adi Sumiwi, Nyi Mekar Saptarini, Jutti Levita   +3 more
doaj   +1 more source

The in vitro and in vivo depigmenting activity of pterostilbene through induction of autophagy in melanocytes and inhibition of UVA-irradiated α-MSH in keratinocytes via Nrf2-mediated antioxidant pathways

Redox Biology, 2021
Pterostilbene (Pt) is a natural polyphenol found in blueberries and several grape varieties. Pt's pharmacological importance was well documented. Nevertheless, the depigmenting effects are not demonstrated.
You-Cheng Hseu, PhD, Yugandhar Vudhya Gowrisankar, PhD, Li-Wei Wang, MS, Yan-Zhen Zhang, MS, Xuan-Zao Chen, MS, Pei-Jane Huang, PhD, Hung-Rong Yen, PhD, Hsin-Ling Yang, PhD   +7 more
doaj   +1 more source

Anti-melanogenic activity of Viola odorata different extracts on B16F10 murine melanoma cells [PDF]

Iranian Journal of Basic Medical Sciences, 2017
Objective(s): In previous studies, antioxidant activity of Viola odorata L. has been demonstrated. In this study, we have investigated the anti-melanogenic effect of extract and fractions of the plant in B16F10 cell line. Materials and Methods: Impact of
Vafa Baradaran Rahimi, Vahid Reza Askari, Seyed Ahmad Emami, Zahra Tayarani-Najaran   +3 more
doaj   +1 more source

Evaluation of [99mTc][Tc-HYNIC/EDDA]-Tyr as a target for metabolic tumor imaging in B16F10 melanoma tumor [PDF]

Asia Oceania Journal of Nuclear Medicine and Biology, 2022
Objective(s): Clinical interest in metabolic imaging of cancer has been growing in recent years. The increase in protein metabolism of cancer cells is interesting target for metabolic tumor imaging, for which radiolabeled amino acids can be applied.
Hemat Yaghoubi Mogadam, Mostafa Erfani, Mohammad Nikpassand, Masoud Mokhtary   +3 more
doaj   +1 more source

Evaluation of anti-proliferative activity of Eryngium caucasicum on melanoma cancer cells

BMC Complementary Medicine and Therapies, 2022
Background The genus Eryngium is a member of the Apiaceae family that has shown different pharmacological effects mainly including anti-inflammatory, analgesic, anti-cancer, hepatoprotective, and anti-oxidant.
Haleh Forouhandeh, Zahra Rezaei Param, Ommoleila Molavi, Parina Asgharian, Vahideh Tarhriz   +4 more
doaj   +1 more source