Results 41 to 50 of about 28,303 (242)
The axis IL-10/claudin-10 is implicated in the modulation of aggressiveness of melanoma cells by B-1 lymphocytes. [PDF]
PLoS ONE, 2017 B-1 lymphocytes are known to increase the metastatic potential of B16F10 melanoma cells via the extracellular signal-regulated kinase (ERK) pathway. Since IL-10 is associated with B-1 cells performance, we hypothesized that IL-10 could be implicated in ...
Elizabeth Cristina Perez +8 more
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Enhancement of electroporation facilitated immunogene therapy via T-reg depletion [PDF]
, 2014 Regulatory T cells (T-regs) can negatively impact tumor antigen-specific immune responses after infiltration into tumor tissue. However, depletion of T-regs can facilitate enhanced anti-tumor responses, thus augmenting the potential for immunotherapies ...
A Testori +28 more
core +1 more source
Effects of T-cadherin expression on B16F10 melanoma cells
Oncology Letters, 2013 Melanoma is one of the most deadly skin cancers. T-cadherin is an atypical member of the cadherin superfamily as it lacks the transmembrane and cytoplasmic domains and is anchored to cell membranes through glycosylphosphatidylinositol (GPI) anchors.
DUAN, XIN-SUO +5 more
openaire +3 more sources
Smad3 promotes cancer progression by inhibiting E4BP4-mediated NK cell development [PDF]
, 2017 published_or_final_versio
Guan, X +11 more
core +5 more sources
Toxicology Reports, 2019 In the study presented here, a novel chlorobenzylated bi-heterocyclic hybrid molecule (7) was synthesized and its structural confirmation was carried out by IR, 1H-NMR, 13C-NMR and CHN analysis data. This compound 7 was subjected to biological study with
Muhammad Athar Abbasi +9 more
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Temporally Programmed CD8α+ DC Activation Enhances Combination Cancer Immunotherapy [PDF]
, 2016 Numerous synergistic cancer immunotherapy combinations have been identified, but the effects of relative dose timing are rarely considered. In established syngeneic mouse tumor models, we found that staggering interferon-α (IFNα) administration after ...
Irvine, Darrell J. +11 more
core +1 more source
Prognostic relationship of metabolic profile obtained of melanoma B16F10
Biomedicine & Pharmacotherapy, 2013 Melanoma is a type of cancer that reaches more people in the world, characterized by genetic mutations that trigger the growth of disorganized cells. The diagnosis of skin tumors by invasive techniques has become a risk to the patients, so the search for new non-invasive techniques has been the subject of research in recent years. The objective of this
Thiago Antonio, Fedele +4 more
openaire +2 more sources
Cells, 2023 Ascorbate acts as a prooxidant when administered parenterally at high supraphysiological doses, which results in the generation of hydrogen peroxide in dependence on oxygen. Most cancer cells are susceptible to the emerging reactive oxygen species (ROS).
Markus Burkard +9 more
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CAV1 inhibits metastatic potential in melanomas through suppression of the Integrin/Src/FAK signaling pathway. [PDF]
, 2010 Caveolin-1 (CAV1) is the main structural component of Caveolae which are plasma membrane invaginations that participate in vesicular trafficking and signal transduction events.
Aplin, Andrew E +9 more
core +2 more sources
CXCL10 promotes melanoma angiogenesis and tumor growth
Animal Cells and SystemsUpregulation of CXC motif chemokine 10 (CXCL10) in melanoma patients has been found to be associated with melanoma progression. However, the role of endogenous CXCL10 from the host in melanoma tumor growth remains unclear.
Bongjun Kim, Yun-Yong Park, Jong-Ho Lee
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