Results 1 to 10 of about 18,845 (218)
CXCL1-CXCR2 axis inhibits melanogenesis through the suppression of the WNT/β-catenin pathway [PDF]
Frontiers in ImmunologyAbnormal skin pigmentation is a common clinical dermatological issue, and its occurrence and development are closely associated with the inflammatory microenvironment.
Yushan Zhang +6 more
doaj +2 more sources
iScience, 2023 Summary: Global warming and rising temperature significantly increase the incidence of heat stress, which is known to affect the process of inflammation and aging. However, the effect of heat stress on skin melanogenesis is not fully known. We found that
Lan Zhang +11 more
doaj +1 more source
DDX3 Upregulates Hydrogen Peroxide-Induced Melanogenesis in Sk-Mel-2 Human Melanoma Cells
Molecules, 2022 DDX3 is a DEAD-box RNA helicase with diverse biological functions through multicellular pathways. The objective of this study was to investigate the role of DDX3 in regulating melanogenesis by the exploring signaling pathways involved.
Sanung Eom +5 more
doaj +1 more source
Spontaneous Formation of Melanin from Dopamine in the Presence of Iron
Antioxidants, 2020 Parkinson’s disease is associated with degeneration of neuromelanin (NM)-containing substantia nigra dopamine (DA) neurons and subsequent decreases in striatal DA transmission. Dopamine spontaneously forms a melanin through a process called melanogenesis.
David M. Hedges +6 more
doaj +1 more source
Plants, 2021 Melanogenesis represents a series of processes that produce melanin, a protective skin pigment (against ultraviolet rays), and determines human skin color. Chemicals reducing melanin production have always been in demand in the cosmetic market because of
Hwang-Ju Jeon +5 more
doaj +1 more source
Natural Product Communications, 2023 Background: Orcinol (3,5-dihydroxytoluene) has been reported to demonstrate inhibitory activity against mushroom tyrosinase. This study aims to investigate the inhibitory effect of orcinol on melanogenesis and its mechanism in B16F10 murine melanoma ...
Chih-Li Yu +4 more
doaj +1 more source
The Function of Autophagy as a Regulator of Melanin Homeostasis
Cells, 2022 Melanosomes are melanocyte-specific organelles that protect cells from ultraviolet (UV)-induced deoxyribonucleic acid damage through the production and accumulation of melanin and are transferred from melanocytes to keratinocytes.
Ki Won Lee +3 more
doaj +1 more source
Molecules, 2022 Plant saponins are abundant and diverse natural products with a great potential for use in drug-discovery research. Here, we evaluated extracts of saponins-rich fractions of argan leaves and argan oil extraction byproducts (shell, pulp, press cake) for ...
Myra O. Villareal +4 more
doaj +1 more source
Molecules, 2021 When skin is exposed to UV radiation, melanocytes produce melanin. Excessive melanin production leads to skin pigmentation, which causes various cosmetic and health problems.
Ji-Hyun Lee +6 more
doaj +1 more source
PLoS ONE, 2020 Fermentation of rice grains requires diverse metabolic enzymes to be synchronously synthesized by the microbial community. Although many studies have used a metaproteomic approach to investigate the roles of microorganisms in improving the flavor of ...
Orrarat Sangkaew +3 more
doaj +1 more source