Results 41 to 50 of about 16,738 (225)

Jeju Magma-Seawater Inhibits α-MSH-Induced Melanogenesis via CaMKKβ-AMPK Signaling Pathways in B16F10 Melanoma Cells

open access: yesMarine Drugs, 2020
Melanin protects skin from ultraviolet radiation, toxic drugs, and chemicals. Its synthesis is sophisticatedly regulated by multiple mechanisms, including transcriptional and enzymatic controls.
Minhyeok Song   +7 more
doaj   +1 more source

Comparative Study of Curcumin and Its Hydrogenated Metabolites, Tetrahydrocurcumin, Hexahydrocurcumin, and Octahydrocurcumin, on Melanogenesis in B16F10 and MNT-1 Cells

open access: yesCosmetics, 2021
Curcumin, a bioactive from Curcuma longa, has been shown to possess anti-melanogenic activity previously; however, the effects of its hydrogenated metabolites (HMs)—Tetrahydrocurcumin (THC), Hexahydrocurcumin (HHC), and Octahydrocurcumin (OHC)—on ...
Shilpi Goenka, Sanford R. Simon
doaj   +1 more source

CHARACTERIZATION OF THE ROLE OF STIM1 IN MELANOGENESIS

open access: yes, 2023
reservedIntracellular Ca2+ homeostasis plays a key role in the control of melanogenesis, the process responsible for the biogenesis of melanosomes, and for melanin accumulation.
DE CIA, ISABELLA
core  

Acetylcholine regulates the melanogenesis of retinal pigment epithelia cells via a cAMP-dependent pathway: A non-neuronal function of cholinergic system in retina

open access: yesHeliyon
The turnover rate of melanogenesis in retinal pigment epithelium (RPE) and its molecular signaling remain unclear. This study aimed to investigate the role of cholinergic signaling in the process of melanogenesis of cultured RPE cells.
Ivan Kong   +6 more
doaj   +1 more source

Src inhibition induces melanogenesis in human G361 cells [PDF]

open access: yes, 2019
The Src kinase family (SKF) includes non‑receptor tyrosine kinases that interact with many cellular cytosolic, nuclear and membrane proteins, and is involved in the progression of cellular transformation and oncogenic activity.
오상호
core   +1 more source

Selaginellin Inhibits Melanogenesis via the MAPK Signaling Pathway

open access: yes, 2022
Hyperpigmented skin diseases such as melasma, freckles, and melanosis usually mar the appearance of patients. Traditional herbal medicines are highly accepted in inhibiting skin pigmentation, with advantages of high efficiency, low cost, and low side ...
Jing Chen   +31 more
core   +1 more source

Melanogenesis in Cryptococcus neoformans [PDF]

open access: yesMicrobiology, 1988
Melanogenesis in Cryptococcus neoformans begins with the oxidation of dihydroxyphenylalanine by the enzyme phenol oxidase. The succeeding steps are very rapid. Two intermediates, dopachrome and 5,6-dihydroxyindole, have been isolated and characterized by high performance liquid chromatography. A pathway of melanin formation in C. neoformans is proposed,
I, Polacheck, K J, Kwon-Chung
openaire   +2 more sources

Inhibition of Melanogenesis by Some Well-Known Polyphenolics: A Review

open access: yes, 2021
Melanogenesis is simply defined as the production of melanin in melanosomes by melanocytes through a complex process. Melanin, a pigment derived from L-tyrosine, comes into two forms, namely eumelanin (brownish to black) and pheomelanin (red to yellow ...
DENİZ, FATMA SEZER   +1 more
core   +1 more source

Chrysoeriol Enhances Melanogenesis in B16F10 Cells Through the Modulation of the MAPK, AKT, PKA, and Wnt/β-Catenin Signaling Pathways

open access: yesNatural Product Communications, 2022
Chrysoeriol is a 3′-O-methoxy flavone, chemically a derivative of luteolin, which is commonly found across the plant kingdom. Chrysoeriol is of great scientific interest because of its promising anti-inflammatory, anti-cancer, antioxidative, anti-lipase,
So-Yeon Oh, Chang-Gu Hyun
doaj   +1 more source

Melanogenesis Using Tyrosinate (Not Tyrosinase)

open access: yes, 2018
We present our initial observations regarding the effect of the presence of L-tyrosinate (= L-tyrosine disodium salt) on the auto- or Fe2+/H2O2-mediated oxidation of various catecholic substances into melanin-like pigments.
Nahfisa, Richardson, Koen, Vercruysse
core   +1 more source

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