Results 41 to 50 of about 16,738 (225)
Melanin protects skin from ultraviolet radiation, toxic drugs, and chemicals. Its synthesis is sophisticatedly regulated by multiple mechanisms, including transcriptional and enzymatic controls.
Minhyeok Song +7 more
doaj +1 more source
Curcumin, a bioactive from Curcuma longa, has been shown to possess anti-melanogenic activity previously; however, the effects of its hydrogenated metabolites (HMs)—Tetrahydrocurcumin (THC), Hexahydrocurcumin (HHC), and Octahydrocurcumin (OHC)—on ...
Shilpi Goenka, Sanford R. Simon
doaj +1 more source
CHARACTERIZATION OF THE ROLE OF STIM1 IN MELANOGENESIS
reservedIntracellular Ca2+ homeostasis plays a key role in the control of melanogenesis, the process responsible for the biogenesis of melanosomes, and for melanin accumulation.
DE CIA, ISABELLA
core
The turnover rate of melanogenesis in retinal pigment epithelium (RPE) and its molecular signaling remain unclear. This study aimed to investigate the role of cholinergic signaling in the process of melanogenesis of cultured RPE cells.
Ivan Kong +6 more
doaj +1 more source
Src inhibition induces melanogenesis in human G361 cells [PDF]
The Src kinase family (SKF) includes non‑receptor tyrosine kinases that interact with many cellular cytosolic, nuclear and membrane proteins, and is involved in the progression of cellular transformation and oncogenic activity.
오상호
core +1 more source
Selaginellin Inhibits Melanogenesis via the MAPK Signaling Pathway
Hyperpigmented skin diseases such as melasma, freckles, and melanosis usually mar the appearance of patients. Traditional herbal medicines are highly accepted in inhibiting skin pigmentation, with advantages of high efficiency, low cost, and low side ...
Jing Chen +31 more
core +1 more source
Melanogenesis in Cryptococcus neoformans [PDF]
Melanogenesis in Cryptococcus neoformans begins with the oxidation of dihydroxyphenylalanine by the enzyme phenol oxidase. The succeeding steps are very rapid. Two intermediates, dopachrome and 5,6-dihydroxyindole, have been isolated and characterized by high performance liquid chromatography. A pathway of melanin formation in C. neoformans is proposed,
I, Polacheck, K J, Kwon-Chung
openaire +2 more sources
Inhibition of Melanogenesis by Some Well-Known Polyphenolics: A Review
Melanogenesis is simply defined as the production of melanin in melanosomes by melanocytes through a complex process. Melanin, a pigment derived from L-tyrosine, comes into two forms, namely eumelanin (brownish to black) and pheomelanin (red to yellow ...
DENİZ, FATMA SEZER +1 more
core +1 more source
Chrysoeriol is a 3′-O-methoxy flavone, chemically a derivative of luteolin, which is commonly found across the plant kingdom. Chrysoeriol is of great scientific interest because of its promising anti-inflammatory, anti-cancer, antioxidative, anti-lipase,
So-Yeon Oh, Chang-Gu Hyun
doaj +1 more source
Melanogenesis Using Tyrosinate (Not Tyrosinase)
We present our initial observations regarding the effect of the presence of L-tyrosinate (= L-tyrosine disodium salt) on the auto- or Fe2+/H2O2-mediated oxidation of various catecholic substances into melanin-like pigments.
Nahfisa, Richardson, Koen, Vercruysse
core +1 more source

