Results 21 to 30 of about 16,738 (225)
DDX3 Upregulates Hydrogen Peroxide-Induced Melanogenesis in Sk-Mel-2 Human Melanoma Cells
Molecules, 2022 DDX3 is a DEAD-box RNA helicase with diverse biological functions through multicellular pathways. The objective of this study was to investigate the role of DDX3 in regulating melanogenesis by the exploring signaling pathways involved.
Sanung Eom +5 more
doaj +1 more source
Melanogenesis and Melasma Treatment [PDF]
, 2021 Melanocytes are highly specialised dendritic cells that transfer melanin to keratinocytes in subcellular lysosome-like organelles called melanosomes, where melanin is synthesised and stored.
Vinardell Martínez-Hidalgo, Ma. Pilar +7 more
core +1 more source
Molecules, 2022 Plant saponins are abundant and diverse natural products with a great potential for use in drug-discovery research. Here, we evaluated extracts of saponins-rich fractions of argan leaves and argan oil extraction byproducts (shell, pulp, press cake) for ...
Myra O. Villareal +4 more
doaj +1 more source
Spontaneous Formation of Melanin from Dopamine in the Presence of Iron
Antioxidants, 2020 Parkinson’s disease is associated with degeneration of neuromelanin (NM)-containing substantia nigra dopamine (DA) neurons and subsequent decreases in striatal DA transmission. Dopamine spontaneously forms a melanin through a process called melanogenesis.
David M. Hedges +6 more
doaj +1 more source
Molecules, 2021 When skin is exposed to UV radiation, melanocytes produce melanin. Excessive melanin production leads to skin pigmentation, which causes various cosmetic and health problems.
Ji-Hyun Lee +6 more
doaj +1 more source
Natural Product Communications, 2023 Background: Orcinol (3,5-dihydroxytoluene) has been reported to demonstrate inhibitory activity against mushroom tyrosinase. This study aims to investigate the inhibitory effect of orcinol on melanogenesis and its mechanism in B16F10 murine melanoma ...
Chih-Li Yu +4 more
doaj +1 more source
Melanogenesis and Hypopigmentation
Indian Journal of Dermatology, 2022 Melanocytes are highly specialized dendritic cells that synthesize and store melanin in subcellular organelles called melanosomes, before transfer to keratinocytes. Melanin is a complex pigment that provides colour and photoprotection to the skin, hair and eyes.
Vinardell Martínez-Hidalgo, Ma. Pilar +2 more
openaire +4 more sources
Plants, 2021 Melanogenesis represents a series of processes that produce melanin, a protective skin pigment (against ultraviolet rays), and determines human skin color. Chemicals reducing melanin production have always been in demand in the cosmetic market because of
Hwang-Ju Jeon +5 more
doaj +1 more source
The Function of Autophagy as a Regulator of Melanin Homeostasis
Cells, 2022 Melanosomes are melanocyte-specific organelles that protect cells from ultraviolet (UV)-induced deoxyribonucleic acid damage through the production and accumulation of melanin and are transferred from melanocytes to keratinocytes.
Ki Won Lee +3 more
doaj +1 more source
Cells, 2021 Fluoroquinolones cause phototoxic reactions, manifested as different types of skin lesions, including hyperpigmentation. The disturbances of melanogenesis indicate that fluoroquinolones may affect cellular processes in melanocytes.
Justyna Kowalska +5 more
doaj +1 more source