Results 11 to 20 of about 13,024 (200)

Melanogenesis Inhibitors

open access: yesActa Dermato-Venereologica, 2018
Abnormally high production of melanin or melanogenesis in skin melanocytes results in hyperpigmentation disorders, such as melasma, senile lentigines or freckles.
Sulekha Kumari   +3 more
doaj   +5 more sources

Mechanisms regulating melanogenesis* [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2013
Skin pigmentation is an important human phenotypic trait whose regulation, in spite of recent advances, has not yet been fully understood. The pigment melanin is produced in melanosomes by melanocytes in a complex process called melanogenesis. The melanocyte interacts with endocrine, immune, inflammatory and central nervous systems, and its activity is
Videira, Inês Ferreira dos Santos   +2 more
openaire   +4 more sources

Melanogenesis and Hypopigmentation

open access: yesIndian Journal of Dermatology, 2022
Melanocytes are highly specialized dendritic cells that synthesize and store melanin in subcellular organelles called melanosomes, before transfer to keratinocytes. Melanin is a complex pigment that provides colour and photoprotection to the skin, hair and eyes.
Vinardell Martínez-Hidalgo, Ma. Pilar   +2 more
openaire   +4 more sources

The Biochemical and Molecular Analysis of Changes in Melanogenesis Induced by UVA-Activated Fluoroquinolones—In Vitro Study on Human Normal Melanocytes

open access: yesCells, 2021
Fluoroquinolones cause phototoxic reactions, manifested as different types of skin lesions, including hyperpigmentation. The disturbances of melanogenesis indicate that fluoroquinolones may affect cellular processes in melanocytes.
Justyna Kowalska   +5 more
doaj   +1 more source

Perspective approaches on melanogenesis inhibition

open access: yesDermatologica Sinica, 2021
Melanogenesis is a melanin-forming process responsible for protecting the skin against ultraviolet radiation damage. An excess production of melanin, however, may result in hyperpigmentation (darkening of the skin) to adverse dermatological effects ...
Aimi Syamima Abdul Manap   +5 more
doaj   +1 more source

Metaproteomic investigation of functional insight into special defined microbial starter on production of fermented rice with melanogenesis inhibition activity.

open access: yesPLoS ONE, 2020
Fermentation of rice grains requires diverse metabolic enzymes to be synchronously synthesized by the microbial community. Although many studies have used a metaproteomic approach to investigate the roles of microorganisms in improving the flavor of ...
Orrarat Sangkaew   +3 more
doaj   +1 more source

Paracrine regulation of melanogenesis [PDF]

open access: yesBritish Journal of Dermatology, 2018
Melanocytes are generally characterized by the basic ability of melanin synthesis and transfer to adjacent keratinocytes. This constitutes an individual skin phenotype and provides epidermal protection from various stimuli, such as ultraviolet irradiation, through a complex process called melanogenesis, which can be regulated by autocrine or paracrine ...
X.H. Yuan, Z.H. Jin
openaire   +2 more sources

Effect of Phlorotannins Isolated From on Melanogenesis in Mouse B16 Melanoma Cells

open access: yesNatural Product Communications, 2021
Phlorotannins isolated from brown algae, such as Eisena bicyclis , have positive physiological effects, including anti-cancer, anti-inflammatory, and anti-Alzheimer’s disease.
Yuki Ohno   +4 more
doaj   +1 more source

Mitofusin-2 Negatively Regulates Melanogenesis by Modulating Mitochondrial ROS Generation

open access: yesCells, 2022
Inter-organellar communication is emerging as one of the most crucial regulators of cellular physiology. One of the key regulators of inter-organellar communication is Mitofusin-2 (MFN2).
Jyoti Tanwar   +12 more
doaj   +1 more source

The mechanisms of melanogenesis inhibition by glabridin: molecular docking, PKA/MITF and MAPK/MITF pathways

open access: yesFood Science and Human Wellness, 2023
Glabridin is the main ingredient of hydrophobic fraction in licorice extract and has been shown to have anti-melanogenesis activity in skins. However, the underlying mechanism(s) remain not completely understood.
Chunxing Pan   +11 more
doaj   +1 more source

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