Results 11 to 20 of about 26,405 (229)
Pigment Intensity in Dogs is Associated with a Copy Number Variant Upstream of KITLG. [PDF]
, 2020 Dogs exhibit a wide variety of coat color types, and many genes have been identified that control pigment production, appearance, and distribution. Some breeds, such as the Nova Scotia Duck Tolling Retriever (NSDTR), exhibit variation in pheomelanin ...
Affolter, Verena +6 more
core +2 more sources
Spontaneous Formation of Melanin from Dopamine in the Presence of Iron
Antioxidants, 2020 Parkinson’s disease is associated with degeneration of neuromelanin (NM)-containing substantia nigra dopamine (DA) neurons and subsequent decreases in striatal DA transmission. Dopamine spontaneously forms a melanin through a process called melanogenesis.
David M. Hedges +6 more
doaj +1 more source
Plants, 2021 Melanogenesis represents a series of processes that produce melanin, a protective skin pigment (against ultraviolet rays), and determines human skin color. Chemicals reducing melanin production have always been in demand in the cosmetic market because of
Hwang-Ju Jeon +5 more
doaj +1 more source
Natural Product Communications, 2023 Background: Orcinol (3,5-dihydroxytoluene) has been reported to demonstrate inhibitory activity against mushroom tyrosinase. This study aims to investigate the inhibitory effect of orcinol on melanogenesis and its mechanism in B16F10 murine melanoma ...
Chih-Li Yu +4 more
doaj +1 more source
The Function of Autophagy as a Regulator of Melanin Homeostasis
Cells, 2022 Melanosomes are melanocyte-specific organelles that protect cells from ultraviolet (UV)-induced deoxyribonucleic acid damage through the production and accumulation of melanin and are transferred from melanocytes to keratinocytes.
Ki Won Lee +3 more
doaj +1 more source
Molecules, 2021 When skin is exposed to UV radiation, melanocytes produce melanin. Excessive melanin production leads to skin pigmentation, which causes various cosmetic and health problems.
Ji-Hyun Lee +6 more
doaj +1 more source
Visible light is a better co-inducer of apoptosis for curcumin-treated human melanoma cells than UVA [PDF]
, 2013 Curcumin attracts worldwide scientific interest due to its anti-proliferative and apoptosis inducing effects on different tumor cells at concentrations ranging from 10 to 150 µM (3.7–55 µg/ml).
Bernd, August +7 more
core +7 more sources
Cells, 2021 Fluoroquinolones cause phototoxic reactions, manifested as different types of skin lesions, including hyperpigmentation. The disturbances of melanogenesis indicate that fluoroquinolones may affect cellular processes in melanocytes.
Justyna Kowalska +5 more
doaj +1 more source
Perspective approaches on melanogenesis inhibition
Dermatologica Sinica, 2021 Melanogenesis is a melanin-forming process responsible for protecting the skin against ultraviolet radiation damage. An excess production of melanin, however, may result in hyperpigmentation (darkening of the skin) to adverse dermatological effects ...
Aimi Syamima Abdul Manap +5 more
doaj +1 more source
Transplantable melanomas in hamsters and gerbils as models for human melanoma : sensitization in melanoma radiotherapy : from animal models to clinical trials [PDF]
, 2018 The focus of the present review is to investigate the role of melanin in the radioprotection of melanoma and attempts to sensitize tumors to radiation by inhibiting melanogenesis. Early studies showed radical scavenging, oxygen consumption and adsorption
Andrzej Słominski +11 more
core +1 more source