Results 11 to 20 of about 18,845 (218)
Acta Dermato-Venereologica, 2018 Abnormally high production of melanin or melanogenesis in skin melanocytes results in hyperpigmentation disorders, such as melasma, senile lentigines or freckles.
Sulekha Kumari +3 more
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Mechanisms regulating melanogenesis* [PDF]
Anais Brasileiros de Dermatologia, 2013 Skin pigmentation is an important human phenotypic trait whose regulation, in spite of recent advances, has not yet been fully understood. The pigment melanin is produced in melanosomes by melanocytes in a complex process called melanogenesis. The melanocyte interacts with endocrine, immune, inflammatory and central nervous systems, and its activity is
Videira, Inês Ferreira dos Santos +2 more
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Mitofusin-2 Negatively Regulates Melanogenesis by Modulating Mitochondrial ROS Generation
Cells, 2022 Inter-organellar communication is emerging as one of the most crucial regulators of cellular physiology. One of the key regulators of inter-organellar communication is Mitofusin-2 (MFN2).
Jyoti Tanwar +12 more
doaj +2 more sources
Isoquercitrin induces melanogenesis in B16F10 melanoma cells and zebrafish via the p38 and PKA/CREB signaling pathways: an experimental study [PDF]
Journal of Yeungnam Medical ScienceBackground Isoquercitrin (IQ), a flavonoid with anticancer, antioxidant, anti-inflammatory, and antiallergic properties, exhibits dual effects on B16F10 melanoma cells by suppressing cell viability and inducing hyperpigmentation.
Jun Ha Lee +3 more
doaj +2 more sources
Drug Design, Development and Therapy, 2019 Deng Zang,1,2 Chao Niu,1 Haji Akber Aisa1 1Key Laboratory of Plant Resources and Chemistry in Arid Regions, State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry ...
Zang D, Niu C, Niu C, Aisa HA
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Melanogenesis and Melasma Treatment [PDF]
, 2021 Melanocytes are highly specialised dendritic cells that transfer melanin to keratinocytes in subcellular lysosome-like organelles called melanosomes, where melanin is synthesised and stored.
Vinardell Martínez-Hidalgo, Ma. Pilar +3 more
core +6 more sources
Melanogenesis Effect of 7-acetoxy-4-methylcoumarin in B16F10 Melanoma Cells
Cosmetics, 2020 The increased interest in anti-whitening dyes has enhanced the research interest to identify efficient melanogenic activators. Melanogenesis is the process of melanin production by melanocytes in the hair follicles and skin, which is mediated by several ...
Ji-Han Sim +4 more
doaj +2 more sources
Cosmetics, 2019 Melanogenesis is a biosynthetic pathway that produces the pigment melanin in human skin. The catalyzation of the key enzyme tyrosinase is the first step in melanogenesis, and the downregulation of tyrosinase enzyme activity is the most reported method ...
Eun Ji Lee, Hwa Jun Cha
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Isolation, Structural Elucidation, and Anti-Melanogenic Activity of a Novel Pectic Polysaccharide From Alhagi camelorum Fisch. [PDF]
Chem BiodiversPolysaccharide extraction from Alhagi camelorum Fisch. was optimized, yielding ACP‐II‐1, a novel GalA‐rich, HG‐dominant pectin (26.145 kDa) containing branched RG‐I domains. ACP‐II‐1 reduced melanogenesis in forskolin‐stimulated B16F10 cells and a zebrafish model.
Liu Z +4 more
europepmc +2 more sources
Melanogenesis and Hypopigmentation
Indian Journal of Dermatology, 2022 Melanocytes are highly specialized dendritic cells that synthesize and store melanin in subcellular organelles called melanosomes, before transfer to keratinocytes. Melanin is a complex pigment that provides colour and photoprotection to the skin, hair and eyes.
Vinardell Martínez-Hidalgo, Ma. Pilar +2 more
openaire +4 more sources