Results 31 to 40 of about 16,738 (225)

Perspective approaches on melanogenesis inhibition

open access: yesDermatologica Sinica, 2021
Melanogenesis is a melanin-forming process responsible for protecting the skin against ultraviolet radiation damage. An excess production of melanin, however, may result in hyperpigmentation (darkening of the skin) to adverse dermatological effects ...
Aimi Syamima Abdul Manap   +5 more
doaj   +1 more source

Modulating skin colour: role of the thioredoxin and glutathione systems in regulating melanogenesis

open access: yes, 2021
Different skin colour among individuals is determined by the varying amount and types of melanin pigment. Melanin is produced in melanocytes, a type of dendritic cell located in the basal layer of the epidermis, through the process of melanogenesis ...
Lu, Yaoying   +2 more
core   +1 more source

Paracrine regulation of melanogenesis [PDF]

open access: yesBritish Journal of Dermatology, 2018
Melanocytes are generally characterized by the basic ability of melanin synthesis and transfer to adjacent keratinocytes. This constitutes an individual skin phenotype and provides epidermal protection from various stimuli, such as ultraviolet irradiation, through a complex process called melanogenesis, which can be regulated by autocrine or paracrine ...
X.H. Yuan, Z.H. Jin
openaire   +2 more sources

Metaproteomic investigation of functional insight into special defined microbial starter on production of fermented rice with melanogenesis inhibition activity.

open access: yesPLoS ONE, 2020
Fermentation of rice grains requires diverse metabolic enzymes to be synchronously synthesized by the microbial community. Although many studies have used a metaproteomic approach to investigate the roles of microorganisms in improving the flavor of ...
Orrarat Sangkaew   +3 more
doaj   +1 more source

Effect of Phlorotannins Isolated From on Melanogenesis in Mouse B16 Melanoma Cells

open access: yesNatural Product Communications, 2021
Phlorotannins isolated from brown algae, such as Eisena bicyclis , have positive physiological effects, including anti-cancer, anti-inflammatory, and anti-Alzheimer’s disease.
Yuki Ohno   +4 more
doaj   +1 more source

Using Melanogenesis to Study Antioxidants

open access: yes, 2018
Building upon our research on the non-enzymatic synthesis of melanins, we explored the possibility that the reactions involved in the synthesis of melanins could serve as the basis for the study of and search for compounds with anti-oxidant properties ...
Iesha, Brown   +2 more
core   +2 more sources

The mechanisms of melanogenesis inhibition by glabridin: molecular docking, PKA/MITF and MAPK/MITF pathways

open access: yesFood Science and Human Wellness, 2023
Glabridin is the main ingredient of hydrophobic fraction in licorice extract and has been shown to have anti-melanogenesis activity in skins. However, the underlying mechanism(s) remain not completely understood.
Chunxing Pan   +11 more
doaj   +1 more source

A Single-Nucleotide Deletion in the Transcription Factor Gene bcsmr1 Causes Sclerotial-Melanogenesis Deficiency in Botrytis cinerea

open access: yesFrontiers in Microbiology, 2017
Botrytis cinerea is an important plant pathogenic fungus with a wide range of host. It usually produces black-colored sclerotia (BS) due to deposition of 1,8-dihydroxynaphthalene melanin in sclerotial melanogenesis. Our previous study (Zhou et al., 2018)
Yingjun Zhou   +6 more
doaj   +1 more source

A potent inhibitor of SIK2, 3, 3', 7-trihydroxy-4'-methoxyflavon (4'-O-methylfisetin), promotes melanogenesis in B16F10 melanoma cells. [PDF]

open access: yesPLoS ONE, 2011
Flavonoids, which are plant polyphenols, are now widely used in supplements and cosmetics. Here, we report that 4'-methylflavonoids are potent inducers of melanogenesis in B16F10 melanoma cells and in mice. We recently identified salt inducible kinase 2 (
Ayako Kumagai   +12 more
doaj   +1 more source

VDAC1 negatively regulates melanogenesis through the Ca 2+ -calcineurin-CRTC1-MITF pathway

open access: yesLife Science Alliance, 2022
This study revealed an important and novel role of mitochondrial VDAC1 in regulating melanogenesis in resting melanocytes through a Ca 2+ -regulated pathway that is independent of the alpha-MSH/UVB pathway.
Jianli Wang   +4 more
doaj   +1 more source

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