Results 31 to 40 of about 26,405 (229)

A Single-Nucleotide Deletion in the Transcription Factor Gene bcsmr1 Causes Sclerotial-Melanogenesis Deficiency in Botrytis cinerea

Frontiers in Microbiology, 2017
Botrytis cinerea is an important plant pathogenic fungus with a wide range of host. It usually produces black-colored sclerotia (BS) due to deposition of 1,8-dihydroxynaphthalene melanin in sclerotial melanogenesis. Our previous study (Zhou et al., 2018)
Yingjun Zhou, Yingjun Zhou, Long Yang, Mingde Wu, Weidong Chen, Guoqing Li, Jing Zhang   +6 more
doaj   +1 more source

VDAC1 negatively regulates melanogenesis through the Ca 2+ -calcineurin-CRTC1-MITF pathway

Life Science Alliance, 2022
This study revealed an important and novel role of mitochondrial VDAC1 in regulating melanogenesis in resting melanocytes through a Ca 2+ -regulated pathway that is independent of the alpha-MSH/UVB pathway.
Jianli Wang, Juanjuan Gong, Qiaochu Wang, Tieshan Tang, Wei Li   +4 more
doaj   +1 more source

Jeju Magma-Seawater Inhibits α-MSH-Induced Melanogenesis via CaMKKβ-AMPK Signaling Pathways in B16F10 Melanoma Cells

Marine Drugs, 2020
Melanin protects skin from ultraviolet radiation, toxic drugs, and chemicals. Its synthesis is sophisticatedly regulated by multiple mechanisms, including transcriptional and enzymatic controls.
Minhyeok Song, Jihyun Lee, Young-Joo Kim, Dang Hieu Hoang, Wonchae Choe, Insug Kang, Sung Soo Kim, Joohun Ha   +7 more
doaj   +1 more source

A potent inhibitor of SIK2, 3, 3', 7-trihydroxy-4'-methoxyflavon (4'-O-methylfisetin), promotes melanogenesis in B16F10 melanoma cells. [PDF]

PLoS ONE, 2011
Flavonoids, which are plant polyphenols, are now widely used in supplements and cosmetics. Here, we report that 4'-methylflavonoids are potent inducers of melanogenesis in B16F10 melanoma cells and in mice. We recently identified salt inducible kinase 2 (
Ayako Kumagai, Nanao Horike, Yudai Satoh, Tatsuya Uebi, Tsutomu Sasaki, Yumi Itoh, Yoshiyuki Hirata, Kozue Uchio-Yamada, Kazuo Kitagawa, Shinichi Uesato, Hidehisa Kawahara, Hiroshi Takemori, Yasuo Nagaoka   +12 more
doaj   +1 more source

Comparative Study of Curcumin and Its Hydrogenated Metabolites, Tetrahydrocurcumin, Hexahydrocurcumin, and Octahydrocurcumin, on Melanogenesis in B16F10 and MNT-1 Cells

Cosmetics, 2021
Curcumin, a bioactive from Curcuma longa, has been shown to possess anti-melanogenic activity previously; however, the effects of its hydrogenated metabolites (HMs)—Tetrahydrocurcumin (THC), Hexahydrocurcumin (HHC), and Octahydrocurcumin (OHC)—on ...
Shilpi Goenka, Sanford R. Simon
doaj   +1 more source

Ultraviolet radiation and melanogenesis [PDF]

, 2004
Light radiation is a part of the electromagnetic radiation, and it consists of the ultraviolet (UV) radiation, visible light, and infrared radiation.
Jovanović Dragan L., Stanojević Milenko R., Stanojević Zorica, Stojiljković Milena   +3 more
core   +1 more source

Bird Integumentary Melanins: Biosynthesis, Forms, Function and Evolution [PDF]

, 2016
Melanins are the ubiquitous pigments distributed in nature. They are one of the main pigments responsible for colors in living cells. Birds are among the most diverse animals regarding melanin-based coloration, especially in the plumage, although they ...
Agrup, Aroca, Bonser, Bortolotti, Brumbaugh, Carr, Chiaverini, Chintala, Colleary, Cott, Darwin, Domyan, D’Ischia, Francisco Solano, García-Borrón, Grande, Ismael Galván, Ito, Jimbow, Jiménez-Cervantes, Kerje, Lin, Liu, Mason, McGraw, McGraw, McGraw, Napolitano, Prota, Prum, Raper, Rorsman, Sato, Searcy, Solano, Straniero, Sultana, Tarafder, Van Grouw, Vinther, Wogelius   +40 more
core   +2 more sources

Acetylcholine regulates the melanogenesis of retinal pigment epithelia cells via a cAMP-dependent pathway: A non-neuronal function of cholinergic system in retina

Heliyon
The turnover rate of melanogenesis in retinal pigment epithelium (RPE) and its molecular signaling remain unclear. This study aimed to investigate the role of cholinergic signaling in the process of melanogenesis of cultured RPE cells.
Ivan Kong, Gary Ka-Wing Yuen, Qi-Yun Wu, Maggie Sui-Sui Guo, Jin Gao, Tina Ting-Xia Dong, Karl Wah-Keung Tsim   +6 more
doaj   +1 more source

A rare case of melanosis of the hard palate mucosa in a patient with chronic myeloid leukemia [PDF]

, 2015
Imatinib Mesylate, also known as Gleevec or ST1-571, is a tyrosine-kinase inhibitor used as the gold standard medication for the chronic myeloid leukemia (CML); Imatinib has indeed deeply revolutionized the CML therapy allowing most patients to have a ...
Bosco, Daniela, Fantozzi, Paolo Junior, Palaia, Gaspare, Romeo, Umberto, Tenore, Gianluca   +4 more
core   +3 more sources

Melanogenesis in Cryptococcus neoformans [PDF]

Microbiology, 1988
Melanogenesis in Cryptococcus neoformans begins with the oxidation of dihydroxyphenylalanine by the enzyme phenol oxidase. The succeeding steps are very rapid. Two intermediates, dopachrome and 5,6-dihydroxyindole, have been isolated and characterized by high performance liquid chromatography. A pathway of melanin formation in C. neoformans is proposed,
I, Polacheck, K J, Kwon-Chung
openaire   +2 more sources