Results 1 to 10 of about 73,036 (190)
MD investigation on the binding of microphthalmia-associated transcription factor with DNA [PDF]
As a main regulator of melanocyte development and an key melanoma oncogene, microphthalmia-associated transcription factor (MITF) is one of the proteins in the basic helix-loop-helix zipper (bHLHZip) transcription factor family. The study on the detailed
Xiang-Feng Wang +6 more
doaj +3 more sources
Transcription factor E3 renal cell carcinoma presenting as secondary hypertension [PDF]
. Microphthalmia-associated transcription factor family (transcription factor E3 or transcription factor EB) translocation renal cell carcinomas (RCCs) are rare neoplasms.
Alain Mwamba Mukendi +3 more
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Microphthalmia-associated transcription factor (MITF) is an essential transactivator in melanin synthesis. To characterize the role of MITF in the pearl mussel Hyriopsis cumingii, the MITF homolog of H. cumingii was isolated.
Jiexuan Shen +4 more
doaj +3 more sources
Inhibitory Effects of Cycloheterophyllin on Melanin Synthesis
This study was performed to clarify the inhibitory effects of cycloheterophyllin on melanin synthesis. In order to elucidate the inhibitory effects of cycloheterophyllin on the B16F10 cell line, cell viability, messenger ribonucleic acid (mRNA ...
Joong-Hyun Shim
doaj +1 more source
The Oncogene Transcription Factor EB Regulates Vascular Functions
Transcription factor EB (TFEB) represents an emerging player in vascular biology. It belongs to the bHLH-leucine zipper transcription factor microphthalmia family, which includes microphthalmia-associated transcription factor, transcription factor E3 and
Gabriella Doronzo +5 more
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Fluoroquinolones cause phototoxic reactions, manifested as different types of skin lesions, including hyperpigmentation. The disturbances of melanogenesis indicate that fluoroquinolones may affect cellular processes in melanocytes.
Justyna Kowalska +5 more
doaj +1 more source
Melanogenesis represents a series of processes that produce melanin, a protective skin pigment (against ultraviolet rays), and determines human skin color. Chemicals reducing melanin production have always been in demand in the cosmetic market because of
Hwang-Ju Jeon +5 more
doaj +1 more source
Fraxinol Stimulates Melanogenesis in B16F10 Mouse Melanoma Cells through CREB/MITF Signaling
Melanin pigment produced in melanocytes plays a protective role against ultraviolet radiation. Selective destruction of melanocytes causes chronic depigmentation conditions such as vitiligo, for which there are very few specific medical treatments. Here,
Sun Young Moon +7 more
doaj +1 more source
Multifaceted activities of transcription factor EB in cancer onset and progression
Transcription factor EB (TFEB) represents an emerging player in cancer biology. Together with microphthalmia‐associated transcription factor, transcription factor E3 and transcription factor EC, TFEB belongs to the microphthalmia family of bHLH‐leucine ...
Elena Astanina +2 more
doaj +1 more source
C-KIT signaling depends on microphthalmia-associated transcription factor for effects on cell proliferation. [PDF]
The development of melanocytes is regulated by the tyrosine kinase receptor c-KIT and the basic-helix-loop-helix-leucine zipper transcription factor Mitf.
Bengt Phung +4 more
doaj +1 more source

