Results 21 to 30 of about 199,125 (144)

Microphthalmia-associated transcription factor suppresses invasion by reducing intracellular GTP pools. [PDF]

Oncogene, 2017
Melanoma progression is associated with increased invasion and, often, decreased levels of microphthalmia-associated transcription factor (MITF). Accordingly, downregulation of MITF induces invasion in melanoma cells; however, little is known about the ...
Bianchi-Smiraglia A, Bagati A, Fink EE, Moparthy S, Wawrzyniak JA, Marvin EK, Battaglia S, Jowdy P, Kolesnikova M, Foley CE, Berman AE, Kozlova NI, Lipchick BC, Paul-Rosner LM, Bshara W, Ackroyd JJ, Shewach DS, Nikiforov MA.   +17 more
europepmc   +2 more sources

Microphthalmia-associated transcription factor regulates the visual cycle genes Rlbp1 and Rdh5 in the retinal pigment epithelium. [PDF]

Sci Rep, 2016
Regeneration of the visual pigment by cells of the retinal pigment epithelium (RPE) is fundamental to vision. Here we show that the microphthalmia-associated transcription factor, MITF, which plays a central role in the development and function of RPE ...
Wen B, Li S, Li H, Chen Y, Ma X, Wang J, Lu F, Qu J, Hou L.   +8 more
europepmc   +2 more sources

Characterizing the Coding Region Determinant-Binding Protein (CRD-BP)-Microphthalmia-associated Transcription Factor (MITF) mRNA interaction. [PDF]

PLoS ONE, 2017
Coding region determinant-binding protein (CRD-BP) binds to the 3'-UTR of microphthalmia-associated transcription factor (MITF) mRNA to prevent its targeted degradation by miR-340.
Gerrit van Rensburg, Sebastian Mackedenski, Chow H Lee   +2 more
doaj   +2 more sources

Cloning of a microphthalmia-associated transcription factor gene and its functional analysis in nacre formation and melanin synthesis in Hyriopsis cumingii

Aquaculture and Fisheries, 2018
Microphthalmia-associated transcription factor (MITF) is an essential transactivator in melanin synthesis. To characterize the role of MITF in the pearl mussel Hyriopsis cumingii, the MITF homolog of H. cumingii was isolated.
Jiexuan Shen, Dandan Huang, Chaohu Sun, Jiale Li, Zhiyi Bai   +4 more
doaj   +2 more sources

Microphthalmia-associated transcription factor mutations are associated with white-spotted coat color in swamp buffalo. [PDF]

Anim Genet, 2015
Summary A candidate gene analysis of the microphthalmia‐associated transcription factor (MITF) gene was used in an attempt to identify the genetic basis for a white‐spotted coat color phenotype in the Asian swamp buffalo (Bubalus bubalis carabanensis ...
Yusnizar Y, Wilbe M, Herlino AO, Sumantri C, Noor RR, Boediono A, Andersson L, Andersson G.   +7 more
europepmc   +2 more sources

Melanogenesis-inducing effect of cirsimaritin through increases in microphthalmia-associated transcription factor and tyrosinase expression. [PDF]

Int J Mol Sci, 2015
The melanin-inducing properties of cirsimaritin were investigated in murine B16F10 cells. Cirsimaritin is an active flavone with methoxy groups, which is isolated from the branches of Lithocarpus dealbatus.
Kim HJ, Kim IS, Dong Y, Lee IS, Kim JS, Kim JS, Woo JT, Cha BY.   +7 more
europepmc   +2 more sources

Regulatory and Functional Connection of Microphthalmia-Associated Transcription Factor and Anti-Metastatic Pigment Epithelium Derived Factor in Melanoma [PDF]

Neoplasia: An International Journal for Oncology Research, 2014
Pigment epithelium-derived factor (PEDF), a member of the serine protease inhibitor superfamily, has potent anti-metastatic effects in cutaneous melanoma through its direct actions on endothelial and melanoma cells.
Asunción Fernández-Barral, Jose Luis Orgaz, Pablo Baquero, Zaheer Ali, Alberto Moreno, María Tiana, Valentí Gómez, Erica Riveiro-Falkenbach, Carmen Cañadas, Sandra Zazo, Corine Bertolotto, Irwin Davidson, Jose Luis Rodríguez-Peralto, Ignacio Palmero, Federico Rojo, Lasse Dahl Jensen, Luis del Peso, Benilde Jiménez   +17 more
doaj   +2 more sources

A novel role for microphthalmia-associated transcription factor-regulated pigment epithelium-derived factor during melanoma progression. [PDF]

Am J Pathol, 2015
Microphthalmia-associated transcription factor (MITF) acts via pigment epithelium-derived factor (PEDF), an antiangiogenic protein, to regulate retinal pigment epithelium migration.
Dadras SS, Lin RJ, Razavi G, Kawakami A, Du J, Feige E, Milner DA, Loda MF, Granter SR, Detmar M, Widlund HR, Horstmann MA, Fisher DE.   +12 more
europepmc   +2 more sources

Betaine reduces cellular melanin content via suppression of microphthalmia-associated transcription factor in B16-F1 murine melanocytes. [PDF]

Food Sci Biotechnol, 2017
Cho BR, Jun HJ, Thach TT, Wu C, Lee SJ.
europepmc   +2 more sources

Transcription factor E3 renal cell carcinoma presenting as secondary hypertension

Current Urology, 2023
. Microphthalmia-associated transcription factor family (transcription factor E3 or transcription factor EB) translocation renal cell carcinomas (RCCs) are rare neoplasms.
Alain Mwamba Mukendi, Gerald Tatenda Mataruka, Ramesh Nadimpalli, Tshisola Miji Kasapato   +3 more
doaj   +1 more source