Results 41 to 50 of about 199,125 (144)

Microphthalmia-associated transcription factor/T-box factor-2 axis acts through Cyclin D1 to regulate melanocyte proliferation. [PDF]

Cell Prolif, 2015
Pan L, Ma X, Wen B, Su Z, Zheng X, Liu Y, Li H, Chen Y, Wang J, Lu F, Qu J, Hou L.   +11 more
europepmc   +2 more sources

Multifaceted activities of transcription factor EB in cancer onset and progression

Molecular Oncology, 2021
Transcription factor EB (TFEB) represents an emerging player in cancer biology. Together with microphthalmia‐associated transcription factor, transcription factor E3 and transcription factor EC, TFEB belongs to the microphthalmia family of bHLH‐leucine ...
Elena Astanina, Federico Bussolino, Gabriella Doronzo   +2 more
doaj   +1 more source

C-KIT signaling depends on microphthalmia-associated transcription factor for effects on cell proliferation. [PDF]

PLoS ONE, 2011
The development of melanocytes is regulated by the tyrosine kinase receptor c-KIT and the basic-helix-loop-helix-leucine zipper transcription factor Mitf.
Bengt Phung, Jianmin Sun, Alexander Schepsky, Eirikur Steingrimsson, Lars Rönnstrand   +4 more
doaj   +1 more source

Microphthalmia-Associated Transcription Factor Expression Levels in Melanoma Cells Contribute to Cell Invasion and Proliferation

Experimental Dermatology, 2015
Jiri Vachtenheim
exaly   +2 more sources

The Microphthalmia-Associated Transcription Factor p.E318K Mutation Does Not Play a Major Role in Sporadic Renal Cell Tumors From Caucasian Patients

Pathobiology, 2016
Christine Stöhr, Kerstin Junker, Paola Ghiorzo   +2 more
exaly   +2 more sources

Microphthalmia in Texel sheep is associated with a missense mutation in the paired-like homeodomain 3 (PITX3) gene. [PDF]

PLoS ONE, 2010
Microphthalmia in sheep is an autosomal recessive inherited congenital anomaly found within the Texel breed. It is characterized by extremely small or absent eyes and affected lambs are absolutely blind. For the first time, we use a genome-wide ovine SNP
Doreen Becker, Jens Tetens, Adrian Brunner, Daniela Bürstel, Martin Ganter, James Kijas, International Sheep Genomics Consortium, Cord Drögemüller   +7 more
doaj   +1 more source

Renal cell carcinoma associated with Xp11.2 translocation/transcription factor E3 gene fusion: an adult case report and literature review

Journal of International Medical Research, 2020
Renal cell carcinoma (RCC) associated with Xp11.2 translocation/transcription factor E3 ( TFE3 ) gene fusion is a rare and independent subtype of RCC included in the classification of MiT (microphthalmia-associated transcriptional factor) family ...
Yuxiong Wang, Yuantao Wang, Mingliang Feng, Xin Lian, Yongsheng Lei, Honglan Zhou   +5 more
doaj   +1 more source

Endolysosomal Cation Channels and MITF in Melanocytes and Melanoma

Biomolecules, 2021
Microphthalmia-associated transcription factor (MITF) is the principal transcription factor regulating pivotal processes in melanoma cell development, growth, survival, proliferation, differentiation and invasion. In recent years, convincing evidence has
Carla Abrahamian, Christian Grimm
doaj   +1 more source

Analysis of the differentially expressed genes and characterization of PIMITF genes of the leopard coral grouper (Plectropomus leopardus)

Aquaculture Reports, 2022
Leopard coral grouper (Plectropomus leopardus) is an indispensable kind of fish in the coral reef ecosystems and marine aquaculture, and the body color of leopard coral grouper is exhibited in black, brown or red.
Hongtao Liu, Chen Dai, Xiaoxin li, Dapeng Luo, He Chen, Jing Cui, Guisen Chen, Qingming Liu, Zhigang Tu, Yun Sun   +9 more
doaj   +1 more source

OCT4 impedes cell fate redirection by the melanocyte lineage master regulator MITF in mouse ESCs

Nature Communications, 2017
Lineage master regulators induce differentiation and how the melanocyte master regulator Microphthalmia-associated transcription factor (MITF) is regulated is unclear.
Danna Sheinboim, Itay Maza, Iris Dror, Shivang Parikh, Vladislav Krupalnik, Rachel E. Bell, Asaf Zviran, Yusuke Suita, Ofir Hakim, Yael Mandel-Gutfreund, Mehdi Khaled, Jacob H. Hanna, Carmit Levy   +12 more
doaj   +1 more source