Results 31 to 40 of about 199,125 (144)

Inhibitory Effects of Cycloheterophyllin on Melanin Synthesis

open access: yesMolecules, 2021
This study was performed to clarify the inhibitory effects of cycloheterophyllin on melanin synthesis. In order to elucidate the inhibitory effects of cycloheterophyllin on the B16F10 cell line, cell viability, messenger ribonucleic acid (mRNA ...
Joong-Hyun Shim
doaj   +1 more source

Ginsenoside Re inhibits melanogenesis and melanoma growth by downregulating microphthalmia-associated transcription factor.

open access: yesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023
Panax ginseng, also known as Korean ginseng, is a traditional remedy widely used in Asian countries. Its major active compounds are ginsenosides, specifically triterpenoid saponins.
S. Hwang, Hye Jung Bang, Hyo-Jong Lee
semanticscholar   +1 more source

The Oncogene Transcription Factor EB Regulates Vascular Functions

open access: yesFrontiers in Physiology, 2021
Transcription factor EB (TFEB) represents an emerging player in vascular biology. It belongs to the bHLH-leucine zipper transcription factor microphthalmia family, which includes microphthalmia-associated transcription factor, transcription factor E3 and
Gabriella Doronzo   +5 more
doaj   +1 more source

The Biochemical and Molecular Analysis of Changes in Melanogenesis Induced by UVA-Activated Fluoroquinolones—In Vitro Study on Human Normal Melanocytes

open access: yesCells, 2021
Fluoroquinolones cause phototoxic reactions, manifested as different types of skin lesions, including hyperpigmentation. The disturbances of melanogenesis indicate that fluoroquinolones may affect cellular processes in melanocytes.
Justyna Kowalska   +5 more
doaj   +1 more source

Fifteen-Year Quest for Microphthalmia-Associated Transcription Factor Target Genes

open access: yesPigment Cell and Melanoma Research, 2010
Corine Bertolotto   +2 more
exaly   +2 more sources

MD investigation on the binding of microphthalmia-associated transcription factor with DNA

open access: yesJournal of Saudi Chemical Society, 2022
As a main regulator of melanocyte development and an key melanoma oncogene, microphthalmia-associated transcription factor (MITF) is one of the proteins in the basic helix-loop-helix zipper (bHLHZip) transcription factor family. The study on the detailed
Xiang-Feng Wang   +6 more
doaj   +1 more source

8-Methoxybutin inhibits α-MSH induced melanogenesis and proliferation of skin melanoma by suppression of the transactivation activity of microphthalmia-associated transcription factor.

open access: yesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022
Microphthalmia-associated transcription factor (MITF) is highly expressed in melanocytes and is the main regulator of melanogenesis and melanocyte cell fate.
Eunji Oh   +7 more
semanticscholar   +1 more source

Molecular Mechanisms of Anti-Melanogenic Gedunin Derived from Neem Tree (Azadirachta indica) Using B16F10 Mouse Melanoma Cells and Early-Stage Zebrafish

open access: yesPlants, 2021
Melanogenesis represents a series of processes that produce melanin, a protective skin pigment (against ultraviolet rays), and determines human skin color. Chemicals reducing melanin production have always been in demand in the cosmetic market because of
Hwang-Ju Jeon   +5 more
doaj   +1 more source

Fraxinol Stimulates Melanogenesis in B16F10 Mouse Melanoma Cells through CREB/MITF Signaling

open access: yesMolecules, 2022
Melanin pigment produced in melanocytes plays a protective role against ultraviolet radiation. Selective destruction of melanocytes causes chronic depigmentation conditions such as vitiligo, for which there are very few specific medical treatments. Here,
Sun Young Moon   +7 more
doaj   +1 more source

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