MD investigation on the binding of microphthalmia-associated transcription factor with DNA
Journal of Saudi Chemical Society, 2022 As a main regulator of melanocyte development and an key melanoma oncogene, microphthalmia-associated transcription factor (MITF) is one of the proteins in the basic helix-loop-helix zipper (bHLHZip) transcription factor family. The study on the detailed
Xiang-Feng Wang +6 more
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MITF (microphthalmia-associated transcription factor) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2013 Review on MITF (microphthalmia-associated transcription factor), with data on DNA, on the protein encoded, and where the gene is implicated.
Riddle, ND, Zhang, P
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Microphthalmia-Associated Transcription Factor [PDF]
The American Journal of Pathology, 2015 This Correspondence relates to the article by Dadras et al (A Novel Role for Microphthalmia-Associated Transcription Factor-Regulated Pigment Epithelium-Derived Factor during Melanoma Progression.
Benilde Jiménez Cuenca +2 more
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Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia-Associated Transcription Factor–Negative Melanoma Cells [PDF]
Cancer Research, 2008 Abstract The origin of tumor heterogeneity is poorly understood, yet it represents a major barrier to effective therapy. In melanoma and in melanocyte development, the microphthalmia-associated transcription factor (Mitf) controls survival, differentiation, proliferation, and migration/metastasis.
Goodall, Jane +8 more
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Transcription factor E3 renal cell carcinoma presenting as secondary hypertension
Current Urology, 2023 . Microphthalmia-associated transcription factor family (transcription factor E3 or transcription factor EB) translocation renal cell carcinomas (RCCs) are rare neoplasms.
Alain Mwamba Mukendi +3 more
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The Microphthalmia-Associated Transcription Factor (MITF) and Its Role in the Structure and Function of the Eye [PDF]
GenesBackground/Objectives: The microphthalmia-associated transcription factor (Mitf) has been found to play an important role in eye development, structure, and function. The Mitf gene is responsible for controlling cellular processes in a range of cell types, contributing to multiple eye development processes.
Thor Eysteinsson +1 more
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Microphthalmia-associated transcription factor is required for mature myotube formation [PDF]
Biochimica et Biophysica Acta (BBA) - General Subjects, 2012 The roles of microphthalmia-associated transcription factor (Mitf) in the skeletal muscle and during myogenesis are unclear.Expression of Mitf in mouse tissues and during myogenesis was evaluated. Effects of Mitf knockdown on myogenesis and gene expression related to myogenesis were subsequently explored. Furthermore, effects of p21, a cyclin-dependent
Ooishi, Ryo +3 more
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Microphthalmia in Texel sheep is associated with a missense mutation in the paired-like homeodomain 3 (PITX3) gene. [PDF]
PLoS ONE, 2010 Microphthalmia in sheep is an autosomal recessive inherited congenital anomaly found within the Texel breed. It is characterized by extremely small or absent eyes and affected lambs are absolutely blind. For the first time, we use a genome-wide ovine SNP
Doreen Becker +7 more
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microRNA-155, induced by interleukin-1ß, represses the expression of microphthalmia-associated transcription factor (MITF-M) in melanoma cells. [PDF]
PLoS ONE, 2015 Loss of expression of surface antigens represents a significant problem for cancer immunotherapy. Microphthalmia-associated transcription factor (MITF-M) regulates melanocyte fate by driving expression of many differentiation genes, whose protein ...
Nathalie Arts +6 more
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Acta Medica Academica, 2010 Microphthalmia-associated transcription factor (MITF) was first discovered as protein coded by gene whose mutations are associated with Waardenburg syndrome. Later, MITF was shown to be key transcription factor regulating melanogenesis.
Ivan Šamija +2 more
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