Results 61 to 70 of about 73,036 (190)

Differentiation of the mononuclear phagocyte system during mouse embryogenesis:the role of transcription factor PU.1 [PDF]

, 1999
During mouse embryogenesis, macrophage-like cells arise first in the yolk sac and are produced subsequently in the liver. The onset of liver hematopoiesis is associated with the transition from primitive to definitive erythrocyte production.
Lichanska, A M, Ostrowski, M C, Henkel, G W, Maki, R A, Murphy, K M, Browne, C M, Hume, D A, McKercher, S R   +7 more
core  

Absence of meningeal mast cells in the Mitf mutant mouse

Frontiers in Cellular Neuroscience
Mast cells (MCs) are located in the meninges of the central nervous system (CNS), where they play key roles in the immune response. MC-deficient mice are advantageous in delineating the role of MCs in the immune response in vivo.
Alba Sabaté San José, Alba Sabaté San José, Petur Henry Petersen   +2 more
doaj   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

MITF and PAX3 play distinct roles in melanoma cell migration; outline of a genetic switch theory involving MITF and PAX3 in proliferative and invasive phenotypes of melanoma

Frontiers in Oncology, 2013
Melanoma is a very aggressive neoplasm with a propensity to undergo progression and invasion early in its evolution. The molecular pathways underpinning invasion in melanoma are now just beginning to be elucidated, but a clear understanding of the ...
Michael R Eccles, Shujie eHe, Antonio eAhn, Lynn eSlobbe, Aaron R Jeffs, Han-Seung eYoon, Bruce C Baguley   +6 more
doaj   +1 more source

6p21 translocation renal cell carcinoma: A case report

Urology Case Reports, 2021
6p21 translocation renal cell carcinoma (RCC) was newly classified in the WHO 2016 classification as a subtype of microphthalmia-associated transcription factor (MIT) family translocation RCC.A 42-year-old man was referred to our hospital with an ...
Yuho Sano, Ryuta Tanimoto, Katsumi Sasaki, Satoko Nakamura, Koichi Mizobuchi, Naoto Kuroda   +5 more
doaj   +1 more source

Identification of novel genes regulating the development of the palate

Developmental Dynamics, EarlyView.
Abstract Background The International Mouse Phenotyping Consortium (IMPC) has generated thousands of knockout mouse lines, many of which exhibit embryonic or perinatal lethality. Using micro‐computed tomography (micro‐CT), the IMPC has created and publicly released three‐dimensional image data sets of embryos from these lethal and subviable lines.
Ashwin Bhaskar, Sophie Astrof
wiley   +1 more source

Immunohistochemical evaluation of microphthalmia-associated transcription factor expression in giant cell lesions [PDF]

Modern Pathology, 2004
Microphthalmia-associated transcription factor (Mitf), a member of the helix-loop-helix transcription factor subfamily, normally expressed in mononuclear and multinucleated osteoclasts, is involved in the terminal differentiation of osteoclasts.
Raja R, Seethala, John R, Goldblum, David G, Hicks, Micheal, Lehman, Jasvir S, Khurana, Terry L, Pasha, Paul J, Zhang   +6 more
openaire   +2 more sources

The membrane-tethered transcription factor ANAC089 serves as redox-dependent suppressor of stromal ascorbate peroxidase gene expression [PDF]

, 2012
Klein P, Seidel T, Stöcker B, Dietz K-J. The membrane-tethered transcription factor ANAC089 serves as redox-dependent suppressor of stromal ascorbate peroxidase gene expression. Frontiers in Plant Science.
Thorsten Seidel, Dietz, Karl-Josef, Benedikt eStöcker, Benedikt Stöcker, Peter eKlein, Klein, Peter, Thorsten eSeidel, Peter Klein, Karl-Josef Dietz, Seidel, Thorsten, Stöcker, Benedikt, Karl-Josef eDietz   +11 more
core   +2 more sources

Sox11 is required to maintain proper levels of Hedgehog signaling during vertebrate ocular morphogenesis. [PDF]

PLoS Genetics, 2014
Ocular coloboma is a sight-threatening malformation caused by failure of the choroid fissure to close during morphogenesis of the eye, and is frequently associated with additional anomalies, including microphthalmia and cataracts.
Lakshmi Pillai-Kastoori, Wen Wen, Stephen G Wilson, Erin Strachan, Adriana Lo-Castro, Marco Fichera, Sebastiano A Musumeci, Ordan J Lehmann, Ann C Morris   +8 more
doaj   +1 more source

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source