Results 51 to 60 of about 16,738 (225)

Unravelling the molecular mechanisms and immune landscape of vitiligo: a comprehensive bioinformatics study on melanogenesis-related genes

Annals of Human Biology
Background Vitiligo is an autoimmune disorder marked by melanocyte destruction and skin depigmentation.Aim To explore the molecular mechanisms underlying melanogenesis and their link to vitiligo.Subjects and methods We analysed three vitiligo-related ...
Binxi Ma, Xiao Wang
doaj   +1 more source

Beyond Molecular Determinism: State‐Convergent Polymerization as a Functional Design Principle Under Chemical Complexity

Advanced Science, EarlyView.
This work introduces state‐convergent polymerization (SCP), a polymerization framework in which chemically diverse reaction pathways converge toward a reproducible functional polymeric state rather than a defined molecular structure. Using melanin and polydopamine as exemplars, SCP explains how robust polymer functions emerge under chemical and ...
Seonki Hong
wiley   +1 more source

Fasting and Refeeding Mediated Phospholipid Remodeling Plays an Important Role in Improving Meat Quality of Aged Laying Hens

Animal Research and One Health, EarlyView.
ABSTRACT This study explored fasting‐induced physiological remodeling effects on meat quality in aged laying hens. Fasting for 15 days (F15) significantly reduced abdominal fat, intermuscular fat width, subcutaneous fat thickness, and liver index versus pre‐fasting (F0) (p < 0.05), which recovered post‐refeeding.
Xiaoran Zhang, Jun Zhang, Yadong Tian, Donghua Li, Yanhua Zhang, Lujie Zhang, Yujie Gong, Xiangtao Kang, Ruirui Jiang   +8 more
wiley   +1 more source

Integrative analysis of transcriptomics and metabolomics to reveal the melanogenesis pathway of muscle and related meat characters in Wuliangshan black-boned chickens

BMC Genomics, 2022
Background Melanin is an important antioxidant in food and has been used in medicine and cosmetology. Chicken meat with high melanin content from black-boned chickens have been considered a high nutritious food with potential medicinal properties.
Tengfei Dou, Shixiong Yan, Lixian Liu, Kun Wang, Zonghui Jian, Zhiqiang Xu, Jingying Zhao, Qiuting Wang, Shuai Sun, Mir Zulqarnain Talpur, Xiaohua Duan, Dahai Gu, Yang He, Yanli Du, Alsoufi Mohammed Abdulwahid, Qihua Li, Hua Rong, Weina Cao, Zhengchang Su, Guiping Zhao, Ranran Liu, Sumei Zhao, Ying Huang, Marinus F. W. te Pas, Changrong Ge, Junjing Jia   +25 more
doaj   +1 more source

Brassinin Abundant in Brassicaceae Suppresses Melanogenesis through Dual Mechanisms of Tyrosinase Inhibition

Foods, 2022
Brassinin is a phytoalexin abundant in plants, especially in cabbage, and has been reported to act as an anti-cancer and anti-inflammatory agent. However, limited studies are available to elucidate the functionalities of brassinin.
Min-Kyeong Lee, Heeyeon Ryu, Hyeon Hak Jeong, Bonggi Lee   +3 more
doaj   +1 more source

Genetic Diversity, Adaptation, Wild Introgression, and Coat Color Mutation of Golden Yak

Animal Research and One Health, EarlyView.
Genetic diversity, adaptation, wild introgression, and coat color mutation of golden yak from two populations on the Qinghai‐Xizang Plateau. ABSTRACT The golden yak lives on the Qinghai‐Xizang Plateau with a golden coat and adapts to high altitudes and strong ultraviolet environment. The golden coat is a prominent phenotype in many domesticated species,
Huixuan Yan, Jialei Chen, Chuzhao Lei, Fengwei Zhang, Shunzhong He, Weiru Song, Hongyan Ma, Shuling Li, Guomei Li, Laba Yongcuo, Jianlin Han, Johannes A. Lenstra, Qiang Zhang, Rende Song, Basang Wangdui, Ningbo Chen   +15 more
wiley   +1 more source

Effect of Aurea Helianthus stem extract on anti-melanogenesis

, 2018
Aurea Helianthus (AH), also known as wild confederate rose or golden sunflower, is a curative herb. It has been used as a medicinal material in China due to its anti-inflammatory, immune regulatory, and anti-oxidant activities.
Song Seok Shin (2671456), Ji Hye Ryu (5685533), Sohun Lee (5685530), Kee Dong Yoon (150814), Yehyang Kim (5685527)   +4 more
core   +1 more source

Role of microRNA508-3p in melanogenesis by targeting microphthalmia transcription factor in melanocytes of alpaca

Animal, 2017
It has been demonstrated that microRNAs (miRNAs) play important roles in the control of melanogenesis and hair color in mammals. By comparing miRNA expression profiles between brown and white alpaca skin, we previously identified miR508-3p as a ...
J. Zhang, Y. Liu, Z. Zhu, S. Yang, K. Ji, S. Hu, X. Liu, J. Yao, R. Fan, C. Dong   +9 more
doaj   +1 more source

Asoprisnil, a Selective Progesterone Receptor Modulator (SPRM), Inhibits Melanosome Export in B16F10 Cells and HEMn-DP Melanocytes

Molecules, 2020
Previous studies have reported that estrogen hormone promotes melanogenesis while progesterone inhibits it. A selective estrogen receptor modulator (SERM), tamoxifen, has been shown to promote melanogenesis; however, to date, there have been no reports ...
Shilpi Goenka, Sanford R. Simon
doaj   +1 more source

Melanogenesis: A Search for Pheomelanin and Also, What Is Lurking Behind Those Dark Colors?

, 2019
We investigated the synthesis of melanin-like materials from DOPA, dopamine, norepinephrine and epinephrine in the presence of L-cysteine. We observed that L-cysteine delayed the formation of pigment from these catecholamines and that the presence of L ...
Venise, Govan, Koen, Vercruysse
core   +1 more source