Results 21 to 30 of about 16,720 (208)

Anti-Metastasis Effects of Ginsenoside Rg3 in B16F10 Cells

Journal of Microbiology and Biotechnology, 2015
Ginsenoside Rg3 is a bioactive ginseng constituent that has been reported to have diverse pathological and physiological effects, including anti-inflammatory and anti-metastatic activities. Metastasis is one of the most important factors involved in patients with melanoma.
Seul Gi, Lee, Young Jin, Kang, Ju-Ock, Nam   +2 more
openaire   +2 more sources

Inhibitory effect of antidepressants on B16F10 melanoma tumor growth [PDF]

Pharmacological Reports, 2013
Antidepressant drugs, like fluoxetine, a selective serotonin reuptake inhibitor, desipramine, a nonselective noradrenaline reuptake inhibitor, and mirtazapine, an antagonist of noradrenaline α2 auto- and heteroreceptors, are widely used for the treatment of depressive symptoms in cancer patients.
Grygier, Beata, Arteta, Beatriz, Kubera, Marta, Basta-Kaim, Agnieszka, Budziszewska, Bogusława, Leśkiewicz, Monika, Curzytek, Katarzyna, Duda, Weronika, Lasoń, Władysław, Maes, Michael   +9 more
openaire   +3 more sources

Photoprotection by dietary phenolics against melanogenesis induced by UVA through Nrf2-dependent antioxidant responses

Redox Biology, 2016
Dietary phenolics may play a protective role in UV-mediated skin pigmentation through their antioxidant and UV-absorbing actions. In this study, we investigated whether genetic silencing of Nrf2, regulating the transcription of antioxidant genes ...
Anyamanee Chaiprasongsuk, Tasanee Onkoksoong, Thanyawan Pluemsamran, Saowalak Limsaengurai, Uraiwan Panich   +4 more
doaj   +1 more source

The Ethanol Extract of Musa sapientum Linn. Peel Inhibits Melanogenesis through AKT Signaling Pathway

Cosmetics, 2021
Hyperpigmentation caused by melanin overproduction can be induced by UV radiation. The quest for effective depigmenting agents continues because many anti-melanin agents have restricted use and/or produce side-effects.
Naphichaya Phacharapiyangkul, Krit Thirapanmethee, Khanit Sa-ngiamsuntorn, Uraiwan Panich, Che-Hsin Lee, Mullika Traidej Chomnawang   +5 more
doaj   +1 more source

RETRACTED Overexpressed PKCδ downregulates the expression of PKCα in B16F10 melanoma: induction of apoptosis by PKCδ via ceramide generation.

PLoS ONE, 2014
In the present study, we observed a marked variation in the expression of PKCα and PKCδ isotypes in B16F10 melanoma tumor cells compared to the normal melanocytes.
Kuntal Halder, Sayantan Banerjee, Anamika Bose, Saikat Majumder, Subrata Majumdar   +4 more
doaj   +1 more source

Effects of T-cadherin expression on B16F10 melanoma cells

Oncology Letters, 2013
Melanoma is one of the most deadly skin cancers. T-cadherin is an atypical member of the cadherin superfamily as it lacks the transmembrane and cytoplasmic domains and is anchored to cell membranes through glycosylphosphatidylinositol (GPI) anchors.
DUAN, XIN-SUO, LU, JIE, GE, ZHI-HUA, XING, EN-HONG, LU, HAI-TAO, SUN, LI-XIN   +5 more
openaire   +3 more sources

Silencing of diphthamide synthesis 3 (Dph3) reduces metastasis of murine melanoma. [PDF]

PLoS ONE, 2012
Melanoma is the most dangerous skin cancer due to its highly metastatic potential and resistance to chemotherapy. Currently, there is no effective treatment for melanoma once it is progressed to metastatic stage. Therefore, further study to elucidate the
Lei Wang, Yu Shi, Peijun Ju, Rui Liu, Siok Ping Yeo, Yinyan Xia, Hamed Owlanj, Zhiwei Feng   +7 more
doaj   +1 more source

(E)-4-(3,4-Dimethoxyphenyl)but-3-en-1-ol Enhances Melanogenesis through Increasing Upstream Stimulating Factor-1-Mediated Tyrosinase Expression.

PLoS ONE, 2015
We investigated the potential melanogenic effect of compounds from Zingiber cassumunar Roxb. Our data revealed that chloroform-soluble extract of Z. cassumunar enhanced melanin synthesis in B16F10 melanoma cells.
Jisu Park, Heesung Chung, Seung Hyun Bang, Ah-Reum Han, Eun-Kyoung Seo, Sung Eun Chang, Duk-Hee Kang, Eok-Soo Oh   +7 more
doaj   +1 more source

The axis IL-10/claudin-10 is implicated in the modulation of aggressiveness of melanoma cells by B-1 lymphocytes. [PDF]

PLoS ONE, 2017
B-1 lymphocytes are known to increase the metastatic potential of B16F10 melanoma cells via the extracellular signal-regulated kinase (ERK) pathway. Since IL-10 is associated with B-1 cells performance, we hypothesized that IL-10 could be implicated in ...
Elizabeth Cristina Perez, Patricia Xander, Maria Fernanda Lucatelli Laurindo, Ronni Rômulo Novaes E Brito, Bruno Camolese Vivanco, Renato Arruda Mortara, Mario Mariano, José Daniel Lopes, Alexandre Castro Keller   +8 more
doaj   +1 more source

Novel Genetic Melanoma Vaccines Based on Induced Pluripotent Stem Cells or Melanosphere-Derived Stem-Like Cells Display High Efficacy in a Murine Tumor Rejection Model

Vaccines, 2020
Therapeutic cancer vaccines have elicited renewed interest due to the development of immune checkpoint inhibitors. The role of these vaccines is to induce specific effector cells for killing cancer cells.
Agnieszka Gąbka-Buszek, Eliza Kwiatkowska-Borowczyk, Jakub Jankowski, Anna Karolina Kozłowska, Andrzej Mackiewicz   +4 more
doaj   +1 more source