Results 21 to 30 of about 28,303 (242)

The atypical chemokine receptor Ackr2 constrains NK cell migratory activity and promotes metastasis [PDF]

open access: yes, 2018
Chemokines have been shown to be essential players in a range of cancer contexts. In this study, we demonstrate that mice deficient in the atypical chemokine receptor Ackr2 display impaired development of metastasis in vivo in both cell line and ...
Brownlie, Demi   +12 more
core   +1 more source

Whitening effect of Brazilin in B16F10 cells [PDF]

open access: yesAsian Journal of Beauty and Cosmetology, 2019
Purpose: This study aimed to identify the whitening effect of brazilin on the B16F10 cell line. Methods: I measured the cell viability, mRNA expression, tyrosinase activity inhibition assay, and melanin contents assay from B16F10 cells. Also, I elucidated the effects of brazilin on tyrosinase-related protein 1 (TYRP1 )/TYRP2 / tyrosinase (TYR ...
openaire   +1 more source

Immunotherapy-induced antibodies to endogenous retroviral envelope glycoprotein confer tumor protection in mice.

open access: yesPLoS ONE, 2021
Following curative immunotherapy of B16F10 tumors, ~60% of mice develop a strong antibody response against cell-surface tumor antigens. Their antisera confer prophylactic protection against intravenous challenge with B16F10 cells, and also cross-react ...
Byong H Kang   +6 more
doaj   +1 more source

The PPARγ Agonist Rosiglitazone Suppresses Syngeneic Mouse SCC (Squamous Cell Carcinoma) Tumor Growth through an Immune-Mediated Mechanism [PDF]

open access: yes, 2019
Recent evidence suggests that PPARγ agonists may promote anti-tumor immunity. We show that immunogenic PDV cutaneous squamous cell carcinoma (CSCC) tumors are rejected when injected intradermally at a low cell number (1 × 106) into immune competent ...
Derr-Yellin, Ethel   +4 more
core   +1 more source

Anti-Metastasis Effects of Ginsenoside Rg3 in B16F10 Cells

open access: yesJournal of Microbiology and Biotechnology, 2015
Ginsenoside Rg3 is a bioactive ginseng constituent that has been reported to have diverse pathological and physiological effects, including anti-inflammatory and anti-metastatic activities. Metastasis is one of the most important factors involved in patients with melanoma.
Seul Gi, Lee   +2 more
openaire   +2 more sources

Emodin inhibits the proliferation and migration of B16F10 cells and induces their apoptosis [PDF]

open access: yesTranslational Cancer Research, 2020
Emodin, extracted from the rhizomes of various Chinese herbs, is a natural anthraquinone derivative with the formula C15H10O5. Many recent studies have shown that emodin has an antitumour effect. In this study, emodin was investigated in vitro to observe its effect on the proliferation, migration, and apoptosis of the B16F10 melanoma cell line.B16F10 ...
Yuan, Mingjie   +13 more
openaire   +2 more sources

Surface immobilization of hexa-histidine-tagged adeno-associated viral vectors for localized gene delivery. [PDF]

open access: yes, 2010
Adeno-associated viral (AAV) vectors, which are undergoing broad exploration in clinical trials, have significant promise for therapeutic gene delivery because of their safety and delivery efficiency.
Bethi, SR   +5 more
core   +2 more sources

Inhibitory effect of antidepressants on B16F10 melanoma tumor growth [PDF]

open access: yesPharmacological Reports, 2013
Antidepressant drugs, like fluoxetine, a selective serotonin reuptake inhibitor, desipramine, a nonselective noradrenaline reuptake inhibitor, and mirtazapine, an antagonist of noradrenaline α2 auto- and heteroreceptors, are widely used for the treatment of depressive symptoms in cancer patients.
Grygier, Beata   +9 more
openaire   +3 more sources

Acenocoumarol, an Anticoagulant Drug, Prevents Melanogenesis in B16F10 Melanoma Cells

open access: yesPharmaceuticals, 2023
Hyperpigmentation can occur in abnormal skin conditions such as melanomas, as well as in conditions including melasma, freckles, age spots, seborrheic keratosis, and café-au-lait spots (flat brown spots). Thus, there is an increasing need for the development of depigmenting agents.
Hyunju Han, Changgu Hyun
openaire   +3 more sources

Pigmented melanoma cell migration study on murine syngeneic B16F10 melanoma cells or tissue transplantation models [PDF]

open access: yes, 2019
Melanoma is a lethal form of skin cancer with poor prognosis, especially due to the early metastatic feature. Recent studies have shown that the melanin pigment influences the nanomechanical properties and, therefore, the metastatic behavior of the ...
Buteică, Sandra Alice   +5 more
core   +2 more sources

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