Dimethyl Itaconate Inhibits Melanogenesis in B16F10 Cells
Itaconate is a metabolite produced to counteract and resolve pro-inflammatory responses when macrophages are challenged with intracellular or extracellular stimuli. In the present study, we have observed that dimethyl itaconate (DMI) inhibits melanogenesis in B16F10 cells.
Bo-Yeong Yu +3 more
openaire +3 more sources
Antiproliferative effect of the jararhagin toxin on B16F10 murine melanoma [PDF]
Malignant melanoma is a less common but highly dangerous form of skin cancer; it starts in the melanocytes cells found in the outer layer of the skin. Jararhagin toxin, a metalloproteinase isolated from Bothrops jararaca snake venom acts upon several biological processes, as inflammation, pain, platelet aggregation, proliferation and apoptosis, though ...
Maria, Durvanei Augusto +3 more
openaire +2 more sources
Associations of PKC Isoforms with the Cytoskeleton of B16F10 Melanoma Cells [PDF]
Although PKC plays a major role in regulating the morphology and function of the cytoskeleton, little is known about in situ associations of specific isoforms with the cytoskeleton. We demonstrate that seven PKC isoforms are expressed in B16F10 melanoma cells and show different levels of induction by serum. Using cell cytoskeleton preparations (CSKs),
J, Szalay +6 more
openaire +2 more sources
Caveolin-1 is a risk factor for postsurgery metastasis in preclinical melanoma models [PDF]
Melanomas are highly lethal skin tumours that are frequently treated by surgical resection. However, the efficacy of such procedures is often limited by tumour recurrence and metastasis. Caveolin-1 (CAV1) has been attributed roles as a tumour suppressor,
Aguilar-Guzmán, L +11 more
core +2 more sources
Expression of the inhibitory Ly49E receptor is not critically involved in the immune response against cutaneous, pulmonary or liver tumours [PDF]
Natural killer (NK) lymphocytes are part of the innate immune system and are important in immune protection against tumourigenesis. NK cells display a broad repertoire of activating and inhibitory cell surface receptors that regulate NK cell activity ...
Filtjens, Jessica +10 more
core +2 more sources
Investigation of microsphere-mediated cellular delivery by chemical, microscopic and gene expression analysis [PDF]
Amino functionalised cross-linked polystyrene microspheres of well defined sizes (0.2-2 mm) have been prepared and shown to be efficient and controllable delivery devices, capable of transporting anything from small dye molecules to bulky proteins into ...
Akhtar +50 more
core +1 more source
Photodynamic Therapy of B16F10 Murine Melanoma with Lutetium Texaphyrin [PDF]
Photodynamic therapy (PDT) of pigmented melanoma has generally been unsuccessful because of insufficient light penetration in such tissues. In this study, the responsiveness of the heavily pigmented B16F10 murine melanoma to lutetium texaphyrin (PCI-0123), a water-soluble sensitizer with strong absorbance in the near infrared (700-760 nm), was examined.
Woodburn, Kathryn W. +4 more
openaire +2 more sources
A characterization of four B16 murine melanoma cell sublines molecular fingerprint and proliferation behavior [PDF]
Background: One of the most popular and versatile model of murine melanoma is by inoculating B16 cells in the syngeneic C57BL6J mouse strain. A characterization of different B16 modified cell sub-lines will be of real practical interest.
Barbu-Tudoran, Lucian +8 more
core +1 more source
The effect of ciprofloxacin on the growth of B16F10 melanoma cells
Objective: The antitumor effect of ciprofloxacin has been widely assessed in-vitro , and positive results have been reported. The aim of this study was to investigate the influence of ciprofloxacin treatment on the growth of B16F10 melanoma cells
Dalal Fares, Jaber +2 more
openaire +2 more sources
Chamaejasmin B Decreases Malignant Characteristics of Mouse Melanoma B16F0 and B16F10 Cells
Chamaejasmin B (CHB), a natural biflavone isolated from Stellera chamaejasme L., has been reported to exhibit anti-cancer properties; however, its effect in melanoma cells is not clear.
Lingling Si +10 more
doaj +1 more source

