Results 71 to 80 of about 3,048,905 (395)

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Weibel Instabilities in Dense Quantum Plasmas [PDF]

open access: yes, 2007
The quantum effect on the Weibel instability in an unmagnetized plasma is presented. Our analysis shows that the quantum effect tends to stabilize the Weibel instability in the hydrodynamic regime, whereas it produces a new oscillatory instability in the
Gardner   +4 more
core   +1 more source

The Instability of Instability

open access: yes, 1991
Abstract : Democratic simple majority voting is perhaps the most widely used method of group decision making in our time. Current theory, based on instability theorems, predicts that a group employing this method will almost always fail to reach a stable conclusion.
openaire   +2 more sources

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

MicroRNA-145 Impairs Classical Non-Homologous End-Joining in Response to Ionizing Radiation-Induced DNA Double-Strand Breaks via Targeting DNA-PKcs

open access: yesCells, 2022
DNA double-strand breaks (DSBs) are one of the most lethal types of DNA damage due to the fact that unrepaired or mis-repaired DSBs lead to genomic instability or chromosomal aberrations, thereby causing cell death or tumorigenesis.
Muddenahalli Srinivasa Sudhanva   +6 more
doaj   +1 more source

Instability Induced Renormalization

open access: yes, 1998
It is pointed out that models with condensates have nontrivial renormalization group flow on the tree level. The infinitesimal form of the tree level renormalization group equation is obtained and solved numerically for the phi4 model in the symmetry ...
Binder   +7 more
core   +2 more sources

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Experimental study on the effect of granular backfill with various gradations on the mechanical behavior of rock

open access: yesInternational Journal of Mining Science and Technology, 2021
Backfilling is a common practice in the mining industry and the backfilling performance plays a significant role in supporting the surrounding rock mass.
Zhihua Le   +4 more
doaj  

Experimental and numerical evaluation on debonding of fully grouted rockbolt under pull-out loading

open access: yesInternational Journal of Coal Science & Technology, 2022
The axial loading in rockbolts changes due to stress redistribution and rheology in the country rock mass. Such a change may lead to debonding at rockbolt to grout interface or rupture of the rockbolt.
Shuisheng Yu, Wancheng Zhu, Leilei Niu
doaj   +1 more source

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