Results 71 to 80 of about 2,390,832 (281)

Integrated Physical Microstructure and Mechanical Performance Analysis of the Failure Mechanism of Weakly Cemented Sandstone Under Long-Term Water Immersion

open access: yesApplied Sciences
The duration of water immersion significantly affects the mechanical response of rock materials. This study investigated the weakly cemented sandstone from the Wulagen Open-pit Mine to examine how varying immersion times affected the mineral composition,
Honglei Liu   +5 more
doaj   +1 more source

Experimental and numerical evaluation on debonding of fully grouted rockbolt under pull-out loading

open access: yesInternational Journal of Coal Science & Technology, 2022
The axial loading in rockbolts changes due to stress redistribution and rheology in the country rock mass. Such a change may lead to debonding at rockbolt to grout interface or rupture of the rockbolt.
Shuisheng Yu, Wancheng Zhu, Leilei Niu
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Research on the Dynamic Response Patterns of Layered Slopes Considering Non-Homogeneity Under Blast-Induced Vibration Effects

open access: yesApplied Sciences
To investigate the dynamic wave propagation characteristics and dynamic response of heterogeneous layered slopes under a blasting vibration, a modeling method considering the slope’s layered dip angle and heterogeneity was proposed. Different dip jointed
Yong Zhao   +5 more
doaj   +1 more source

Curvature scalar instability in f(R) gravity [PDF]

open access: yes, 2006
An instability in the presence of matter in theories of gravity which include a 1/R correction in the gravitational action has been found by Dolgov and Kawasaki. In the present paper this instability is discussed for f(R) gravity in general.
Allemandi   +51 more
core   +4 more sources

Wrist Instability [PDF]

open access: yesScandinavian Journal of Surgery, 2008
The topic of wrist or carpal instability has been a source of confusion and miscommunication for decades. The terminology can often be difficult to understand and one surgeon's concept of instability may be completely different from another's. This is by no means a comprehensive review of carpal instability, which has often been the focus of numerous ...
B T, Carlsen, A Y, Shin
openaire   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Analysis of Surrounding Rock Stability Based on Refined Geological and Mechanical Parameter Modeling—A Case Study

open access: yesApplied Sciences
Metallic ore deposits are generally formed through magmatic intrusions, followed by metamorphism. The geological structures in such regions are often complex, with mechanical parameters exhibiting significant variability.
Guangzhi Chai   +5 more
doaj   +1 more source

ID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stability

open access: yesNature Communications, 2017
MDC1 is a key component of the DNA damage response and interacts with several factors such as γ-H2AX. Here the authors show that MDC1 interacts with ID3, facilitating MDC1 recruitment to sites of damage and repair of breaks.
Jung-Hee Lee   +11 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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