Results 141 to 150 of about 313,273 (308)

The relative effects of input and output based instruction on the development of L2 knowledge and the relationships with individual differences in working memory

open access: yesAsian-Pacific Journal of Second and Foreign Language Education
While the relative effects of Processing instruction (PI) and various types of output-based instruction have been widely examined, the types of L2 knowledge generated after receiving instruction are under-researched.
Yan Liang, Lawrence Jun Zhang
doaj   +1 more source

Examining How Residential Colleges Inspire the Life of the Mind [PDF]

open access: yes, 2012
Residential colleges in large, public research universities purport to create a small liberal arts environment with the resources of a major university, but little empirical attention has been paid to their claims of effectiveness.
Jessup-Anger, Jody
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

The impact of genre-based instruction on Saudi university students’ English writing performance and motivation: a mixed-method study

open access: yesFrontiers in Psychology
Despite the important role motivation plays in students’ writing learning and development, not much attention has been given to experimenting particular instructional techniques for developing students’ writing motivation.
Muhammad M. M. Abdel Latif   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Making the Invisible, Visible: RtI and Reading Comprehension

open access: yes, 2016
For the better part of a century the educational community has had increased focus on the importance of reading. The publication of Why Johnny Can\u27t Read and What You Can Do About It (Flesch, 1955) began the surge of effort to better understand the ...
Hart, Jonathan, Stebick, Divonna M.
core  

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