Results 81 to 90 of about 393,540 (338)

Determinants of Activity Levels in African Americans With Mild Cognitive Impairment. [PDF]

, 2016
Engaging in cognitive, social, and physical activities may prevent cognitive decline. In a sample of older African Americans with mild cognitive impairment (MCI; N=221), we investigated the cross-sectional relationships between activity levels and ...
Casten, PhD, Robin J., Leiby, PhD, Benjamin E., Rovner, MD, Barry W.   +2 more
core   +2 more sources

Validation of the Everyday Technology Use Questionnaire in a Japanese context

Hong Kong Journal of Occupational Therapy, 2015
Background/Objective: The Everyday Technology Use Questionnaire (ETUQ), which evaluates the perceived relevance of and the perceived ability in everyday technology (ET) use, has demonstrated acceptable psychometric properties in Swedish studies of older ...
Camilla Malinowsky, Anders Kottorp, Rumi Tanemura, Eric Asaba, Toru Nagao, Kazue Noda, Jiro Sagara, Peter Bontje, Lena Rosenberg, Louise Nygård   +9 more
doaj   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Učinak aktivnosti svakodnevnog života i sposobnosti za brigu o sebi na depresiju kod starijih osoba na sjeveru Turske [PDF]

, 2019
This study aimed to determine the effects of daily living activities and self-care capacity on depression of the elderly in northern Turkey. The study was conducted with participation of 451 voluntary elderly indi-viduals.
Zeliha Koç, Zeynep Sağlam
core   +2 more sources

Functional Status in Older Women Diagnosed with Pelvic Organ Prolapse [PDF]

, 2016
Background—Functional status plays an important role in the comprehensive characterization of older adults. Functional limitations are associated with an increased risk of adverse treatment outcomes, but there is limited data on the prevalence of ...
Couri, Bruna M., Guralnik, Jack, Koroukian, Siran M., Mahajan, Sangeeta T., Richter, Holly E., Sanses, Tatiana V.D., Schiltz, Nicholas K., Warner, David F.   +7 more
core   +4 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

The Role of Occupational Therapy and the Use of Physical Agent Modalities and Occupational Therapy Interventions to Decrease Pain Associated with Endometriosis to Provide Increased Occupational Performance in Leisure Activities [PDF]

, 2023
Endometriosis is a condition that can affect women of reproductive age (Kalaitzopoulos et al., 2021). This condition causes endometrial-type tissue to grow outside of the uterus (Kalaitzopoulos et al., 2021). Women diagnosed with endometriosis often have
Boykin, Keisa, Pearce, Ciara Autumn
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Measuring unmet need for social care among older people

, 2011
Recent spending cuts in the area of adult social care raise policy concerns about the proportion of older people whose need for social care is not met. Such concerns are emphasised in the context of population ageing and other demographic changes.
Evandrou, Maria, Falkingham, Jane, Luff, Rebekah, Shaw, Richard, Vlachantoni, Athina, Willis, Rosalind   +5 more
core  

The IMMED Project: Wearable Video Monitoring of People with Age Dementia [PDF]

, 2010
International audienceIn this paper, we describe a new application for multimedia indexing, using a system that monitors the instrumental activities of daily living to assess the cognitive decline caused by dementia.
André-Obrecht, Régine, Benois-Pineau, Jenny, Dartigues, Jean-François, Dovgalecs, Vladislavs, El Khoury, Elie, Gaëstel, Yann, Joly, Philippe, Karaman, Svebor, Mégret, Rémi, Pinquier, Julien, Wannous, Hazem   +10 more
core   +1 more source