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Insulin Signaling and Insulin Resistance [PDF]
Journal of Investigative Medicine, 2013 Insulin resistance or its sequelae may be the common etiology of maladies associated with metabolic syndrome (eg, hypertension, type 2 diabetes, atherosclerosis, heart attack, stroke, and kidney failure). It is thus important to understand those factors that affect insulin sensitivity.
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A Multicenter Survey of Type I Diabetes Mellitus in Chinese Children
Frontiers in Endocrinology, 2021 PurposeTo investigate the features and treatment status of children with type 1 diabetes mellitus (T1DM) in China.MethodsWe recruited patients <14 years of age with T1DM from 33 medical centers in 25 major cities of China between January 2012 and ...
Ling Hou +34 more
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Recombinant canine single chain insulin analogues: Insulin receptor binding capacity and ability to stimulate glucose uptake [PDF]
, 2014 Virtually all diabetic dogs require exogenous insulin therapy to control their hyperglycaemia. In the UK, the only licensed insulin product currently available is a purified porcine insulin preparation.
Angela L. Holder +23 more
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The Lancet, 1969 The idea that excessive concentrations of insulin might contribute to the development of atherosclerosis appeared in the mid 1960s and the evidence was first reviewed in a paper published in 1969 [1]. Since then, data, both clinical and experimental, has continued to accumulate, most of it supportive of the hypothesis, although some of the details have
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Cellular & Molecular Biology LettersBackground The trafficking of cargoes from endosomes to the trans-Golgi network requires numerous sequential and coordinated steps. Cargoes are sorted into endosomal-derived carriers that are transported, tethered, and fused to the trans-Golgi network ...
Jérôme Gilleron +4 more
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International Journal of Food Properties, 2020 Existing evidence on the possible effects of saffron on glycemic indices were inconclusive. The aim of the present systematic review and meta-analysis was to clarify the effects of saffron supplementation on glycemic indices, including fasting blood ...
Sara Sohaei +3 more
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The Sulfonylurea Drug, Glimepiride, Stimulates Glucose Transport, Glucose Transporter Translocation, and Dephosphorylation In Insulin-Resistant Rat Adipocytes In Vitro [PDF]
, 1993 Sulfonylurea drugs are widely used in the therapy of NIDDM. The improvement of glucose tolerance after long-term treatment of NIDDM patients with the drug can be explained by stimulation of glucose utilization in peripheral tissues that are characterized
Müller, Günter, Wied, Susanne
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Frontiers in Neuroscience, 2020 BackgroundIndividuals with Alzheimer’s Disease (AD) are often characterized by systemic markers of insulin resistance; however, the broader effects of AD on other relevant metabolic hormones, such as incretins that affect insulin secretion and food ...
Jill K. Morris +22 more
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The Effect of Ramadan Fasting on Hypothalamic Pituitary Ovarian (HPO) Axis in Women with Polycystic Ovary Syndrome [PDF]
Women’s Health Bulletin, 2014 Background: Ramadan fasting is a religious practice and an exceptional ritual compared to all other religious conventions. The aim of fasting in Ramadan is to establish a proper religious model of self-control and healthy lifestyle.
Farideh Zangeneh +4 more
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Frontiers in Psychiatry, 2021 Background: No study investigated the association between stress exposure in different stages of life and metabolic dysfunction.Aim: We explore the association between stress exposure and several biomarkers related to glucose metabolism (insulin, c ...
Sarah Tosato +12 more
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