Results 11 to 20 of about 1,421,988 (303)

Insulin Analogues for Insulin Receptor Studies and Medical Applications [PDF]

, 2012
The structure of insulin molecule was determined by Dorothy Hodgkin in 1969. Subsequently, it has been established that insulin must rearrange upon binding to its receptor (Insulin Receptor – IR).
Watson, Christopher John
core   +6 more sources

Associations of insulin and insulin-like growth factors with physical performance in old age in the boyd orr and caerphilly studies. [PDF]

, 2012
OBJECTIVE: Insulin and the insulin-like growth factor (IGF) system regulate growth and are involved in determining muscle mass, strength and body composition.
Gallacher, J, Holly, JM, Martin, RM, Birnie, K, Gunnell, D, Ben-Shlomo, Y, Ebrahim, S, Bayer, A   +7 more
core   +5 more sources

Insulin begets insulin [PDF]

European Journal of Endocrinology, 1999
The pathogenesis of type 2 diabetes is characterized by insulin resistance, primarily in skeletal muscle, fat and liver, and a relative failure of the pancreatic b-cell (1, 2). Considerable controversy surrounds the issue of which of these deficiencies is the primary cause of diabetes.
openaire   +2 more sources

Acknowledgement to reviewers

Journal of Metabolic Health, 2018
No abstract available.
Editorial Office
doaj   +1 more source

Role of some serum biomarkers in the early detection of diabetic cardiomyopathy

Future Science OA, 2021
Aim: To assess the role of serum biomarkers in early prediction of diabetic cardiomyopathy. Materials and methods: The participants were three groups of Type 2 diabetes mellitus (DM) patients having diastolic dysfunction (DM-DD), systolic dysfunction (DM-
Amany H Abdelrahman, Iman I Salama, Somaia I Salama, Dalia M Elmosalami, Mona H Ibrahim, Eman M Hassan, Mark O Dimitry, Zahraa I Aboafya, Mohammad Gouda Mohammad, Mohamed Amin   +9 more
doaj   +1 more source

The role of insulin receptor substrate 2 in hypothalamic and β cell function [PDF]

, 2005
Insulin receptor substrate 2 (Irs2) plays complex roles in energy homeostasis. We generated mice lacking Irs2 in β cells and a population of hypothalamic neurons (RIPCreIrs2KO), in all neurons (NesCreIrs2KO), and in proopiomelanocortin neurons ...
Hisadome, Kazunari, Choudhury, Agharul I., Smith, Mark A., Simmgen, M., Diakonov, Ivan, Allison W. Xu, Bedford, D.C., Michael L.J. Ashford, Speakman, J.R., Helen Heffron, Bedford, David C., Selman, Colin, Marc Claret, Xu, Allison W., Kazunari Hisadome, Claret, Marc, MacColl, Gavin, Bell, Jimmy D., Speakman, John R., Heffron, H., Melanie Clements, Barsh, Gregory S., Agharul I. Choudhury, Choudhury, A.I., Heffron, Helen, Hind Al-Qassab, Xu, A.W., Vazira Moosajee, Withers, D.J., Hisadome, K., Barsh, G.S., Clements, Melanie, Mark A. Smith, Ashford, Michael L.J.; id_orcid, Withers, Dominic J., Moosajee, Vazira, Dominic J. Withers, Claret, M., MacColl, G., Selman, C., Ivan Diakonov, Al-Qassab, H., Al-Qassab, Hind, Moosajee, V., Gavin MacColl, Simmgen, Marcus, Bell, J.D., Smith, M.A., Ashford, M.L.J., Gregory S. Barsh, Diakonov, I., Batterham, R.L., David C. Bedford, Batterham, Rachel L., Colin Selman, Jimmy D. Bell, Clements, M., Marcus Simmgen, Rachel L. Batterham, John R. Speakman   +59 more
core   +1 more source

Combinatorial treatment of mupirocin nanomicelle in insulin-based gel for wound healing in diabetic rats

Medical Journal of Babylon, 2023
Background: Diabetic wounds remain an important clinical challenge over the past few decades. Nanodrug delivery systems play a crucial role in the treatment of chronic infections and wound healing.
Maysaa Banay Zubairi, Abdulkareem Hameed Abd, Mohammed Sabar Al-lami   +2 more
doaj   +1 more source

Fat oxidation, fitness and skeletal muscle expression of oxidative/lipid metabolism genes in South Asians: implications for insulin resistance? [PDF]

, 2010
<p><b>Background:</b> South Asians are more insulin resistant than Europeans, which cannot be fully explained by differences in adiposity. We investigated whether differences in oxidative capacity and capacity for fatty acid utilisation
Nita G Forouhi, Jason M R Gill, Hall, L.M.L., Hariharan, Narayanan, Salt, I.P., Hall, Lesley M L, Wilson, John, Niall G. MacFarlane, Niall G MacFarlane, Sattar, N., Milne, Gillian R, Gillian R Milne, MacFarlane, N.G., Gill, Jason M R, Gill Jason M. R., Lesley M. L. Hall, Moran Colin N., John Wilson, Sattar Naveed, Jason M. R. Gill, Colin N Moran, Gillian R. Milne, MacFarlane Niall G., Lesley M L Hall, Forouhi, N.G., MacFarlane, Niall G, Hariharan, N., Ian P Salt, Colin N. Moran, Hariharan Narayanan, Milne, G.R., Sattar, Naveed, Gill, J.M.R., Moran, C.N., Milne Gillian R., Nita G. Forouhi, Forouhi Nita G., Salt Ian P., Naveed Sattar, Narayanan Hariharan, Moran, Colin Neil, Hall Lesley M. L., Forouhi, Nita G, Salt, Ian P, Ian P. Salt, Wilson John   +45 more
core   +1 more source

The prevalence of the metabolic syndrome in Portugal: the PORMETS study

BMC Public Health, 2017
Background The PORMETS study was designed to estimate the prevalence of metabolic syndrome and its determinants in the overall and administrative regions of the Portuguese mainland.
Luís Raposo, Milton Severo, Henrique Barros, Ana Cristina Santos   +3 more
doaj   +1 more source

Effect of the dietary fat quality on insulin sensitivity. [PDF]

, 2008
Recent evidence shows that specific fatty acids affect cell metabolism, modifying the balance between fatty acid oxidation and lipogenesis. These effects may have important implications in addressing the present epidemic of nutrition-related chronic ...
Aguirre, Carolina A, Uauy Dagach-Imbarack, Ricardo, Galgani Fuentes, José, Díaz Bustos, Erik, Aguirre, Carolina A., Galgani, José E, Uauy, Ricardo D, Díaz, Erik O   +7 more
core   +1 more source