Results 41 to 50 of about 2,026,798 (359)

Some specificities in the management of hyperglycemia in patients with diabetic kidney disease [PDF]

Vojnosanitetski Pregled, 2016
nema
Dragović Tamara, Marinković Dejan, Kiković Saša, Pejović Janko, Hajduković Zoran   +4 more
doaj   +1 more source

Molecular mechanisms of insulin resistance in chronic liver disease [PDF]

, 2008
The work presented here analyses the role of PP2A in the dysregulation of glucose metabolism in the setting of chronic hepatitis C. We propose a new model for virus induced insulin resistance development through the overexpression of PP2A in the liver ...
Bernsmeier, Christine
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Diagnostic and referral pathways in patients with rare lipodystrophy and insulin-resistance syndromes: key milestones assessed from a national reference center

Orphanet Journal of Rare Diseases
Background Rare syndromes of lipodystrophy and insulin-resistance display heterogeneous clinical expressions. Their early recognition, diagnosis and management are required to avoid long-term complications.
Bruno Donadille, Sonja Janmaat, Héléna Mosbah, Inès Belalem, Sophie Lamothe, Mariana Nedelcu, Anne-Sophie Jannot, Sophie Christin-Maitre, Bruno Fève, Camille Vatier, Corinne Vigouroux   +10 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Assessment of diabetes mellitus type 2 treatment costs in the Republic of Serbia [PDF]

Vojnosanitetski Pregled, 2009
Background/Aim. High morbidity and mortality rates, chronic course of disease and numerous clinical complications, make diabetes mellitus (DM) type 2 bear significant financial burden for healthcare system of Serbia.
Biorac Nenad, Jakovljević Mihajlo B., Stefanović Danka, Perović Saša, Janković Slobodan   +4 more
doaj   +1 more source

Insulin Analogues for Insulin Receptor Studies and Medical Applications [PDF]

, 2012
The structure of insulin molecule was determined by Dorothy Hodgkin in 1969. Subsequently, it has been established that insulin must rearrange upon binding to its receptor (Insulin Receptor – IR).
Watson, Christopher John
core  

Hypothalamically-Induced Insulin Release and its Potentiation During Oral and Intravenous Glucose Loads [PDF]

, 1984
Male Wistar rats were provided with bilateral cannulas in the lateral hypothalamic area (LHA) and cannulas in the left and right jugular vein. Freely moving rats provided in this way with cannulas were infused with transmitters in the LHA and with ...
Steffens, A.B., Steffens, A.B.,, Luiten, P.G.M., Kuipers, F.; id_orcid, Luiten, P.G.M.,, Flik, G., Flik, G.,, Kuipers, F.,, Kuipers, F., Lotter, E.C., Lotter, E.C.,   +10 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability

Journal of Diabetes Research, 2018
Variability in the effect of subcutaneously administered insulin represents a major challenge in insulin therapy where precise dosing is required in order to achieve targeted glucose levels.
A. K. J. Gradel, T. Porsgaard, J. Lykkesfeldt, T. Seested, S. Gram-Nielsen, N. R. Kristensen, H. H. F. Refsgaard   +6 more
doaj   +1 more source