Regulation of human fibroblast insulin-like growth factor (IGF)-binding proteins by IGF-1 and cytokines, mechanisms of action and effects upon IGF bioactivity [PDF]
, 1995 PhDThe insulin-like growth factors, IGF-I and IGF-II, are ubiquitous polypeptide molecules that have mitogenic and metabolic actions in a wide variety of cell types, and consequently play a major role in mammalian growth and development.
Yateman, Martin Edward
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Insulin-like growth factor (IGF)-I and IGF binding proteins axis in diabetes mellitus [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2015 Increasing evidence suggests an important role of the insulin-like growth factor (IGF)-IGF binding protein (IGFBP) axis in the maintenance of normal glucose and lipid metabolism. Significant changes occur in the local IGF-I-IGFBPs environment in response
Min Sun Kim, Dae-Yeol Lee
doaj +1 more source
Consequences of Postnatally Elevated Insulin-Like Growth Factor-II in Transgenic Mice: Endocrine Changes and Effects on Body and Organ Growth. [PDF]
, 1994 Insulin-like growth factor-II (IGF-II) is an important regulator of embryonic growth and differentiation, but its function in postnatal life is unclear. To address this point, we generated transgenic mice harboring fusion genes in which a human IGF-II
E. Wolf +10 more
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Estudio inmunocitoquímico y molecular de cultivo primario de tejido molar
Biomédica: revista del Instituto Nacional de Salud, 2006 Introducción. La enfermedad trofoblástica gestacional comprende un conjunto de patologías caracterizadas por crecimiento e invasión anómalos del trofoblasto.
Yinth Andrea Bernal +6 more
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Identification and characterization of insulin-like growth factor receptors on adult rat cardiac myocytes: linkage to inositol 1,4,5-trisphosphate formation. [PDF]
, 1992 Cultured cardiac myocytes from adult Sprague-Dawley rats express both insulin-like growth factor-I (IGF-I) receptors and insulin-like growth factor-II/mannose 6-phosphate (IGF-II/Man6P) receptors and respond to IGF-I with a dose-dependent accumulation of
Berg, Ingeborg +6 more
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Endocrinology Research and Practice, 2023 Objective: Energy deprivation induces changes in various components of the “growth hormone”/“insul in-like growth factor-I” axis; however, it remains unclear whether Ramadan fasting could alter which ones in response to food deprivation.
Majid Reza Sheikh Rezaee +4 more
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Insulin-like growth factor binding proteins initiate cell death and extracellular matrix remodeling in the mammary gland [PDF]
, 2005 We have demonstrated that insulin-like growth factor binding protein-5 (IGFBP-5) production by mammary epithelial cells increases dramatically during forced involution of the mammary gland in rats, mice and pigs.
Beattie, J +19 more
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Biomédica: revista del Instituto Nacional de Salud, 2006 Introducción. La citología cervico-uterina como prueba de tamizaje del cáncer cervical tiene limitaciones. Un marcador que permita identificar mujeres en riesgo de desarrollar este cáncer sería de utilidad para prevenir el desarrollo de esta enfermedad ...
Martha Lucía Serrano +4 more
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Erythropoiesis, serum erythropoietin, and serum IGF-I in rats during accelerated growth [PDF]
, 1990 In this study we have examined the correlation between activity of erythropoiesis and serum concentrations of erythropoietin and insulin-like growth factor I in male and female rats during accelerated growth (day 30-90).
Kurtz, Armin +11 more
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Insulin-like growth factor-I and its binding proteins in healthy mothers and their newborns [PDF]
Einstein (São Paulo), 2004 Objective: To determine serum levels of insulin-like growth factor-I, free insulin-like growth factor-I and its binding proteins in maternalserum and in cord blood of two groups of newborns with differentbirth weights.
Rosanna Velleca Lima +3 more
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