Results 71 to 80 of about 34,204,101 (306)
Tumor-stroma derived gene expression patterns as prognosticators in breast cancer [PDF]
, 2010 The stroma, which embeds epithelial cells, plays a major role in the shaping and physiological regulation of animal organs such as the breast. Aberrant functioning of the stroma was found to support tumorigenesis and cancer progression.
Rajski, Michal
core +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Insulin-like growth factor I in essential hypertension
Kidney International, 1999 mmol/liter; serum cholesterol, 5.95 mmol/liter; serum triglycerides, 1.40 mmol/liter; serum potassium, 4 mmol/liter; serum creatinine, 95 mmol/liter (1.1 mg/dl); creatinine clearance, 112 ml/min/1.73 m body surface; and 24-hour urine albumin excretion, 245 mg. Urinalysis revealed no other abnormalities.
Principal discussant, , Díez, Javier
openaire +3 more sources
Measurement of Salivary Insulin-Like Growth Factor-I in Acromegaly: Comparison with Serum Insulin-Like Growth Factor-I and Growth Hormone Concentrations [PDF]
cclm, 1994 The aim of this study was to establish the concentration of insulin-like growth factor-I (IGF-I) in saliva of acromegalic patients, and to compare it with the basal levels of serum IGF-I and growth hormone. IGF-I was determined in extracted serum or neat saliva by a disequilibrium RIA using antibodies and iodinated ligand from Amersham and WHO 87/518 ...
Halimi, S. +5 more
openaire +4 more sources
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
IGF2R (insulin-like growth factor 2 receptor) [PDF]
, 2004 Review on IGF2R (insulin-like growth factor 2 receptor), with data on DNA, on the protein encoded, and where the gene is ...
Killian, JK
core +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
IGF1R (insulin-like growth factor 1 receptor) [PDF]
, 2009 Review on IGF1R (insulin-like growth factor 1 receptor), with data on DNA, on the protein encoded, and where the gene is ...
Bentov, Y, Werner, H
core +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source