Results 191 to 200 of about 428,788 (310)

Normative data for insulin-like growth factor-1 and insulin-like growth factor binding protein-3 and their determinants in healthy adult males from india: the INDIIGo study. [PDF]

Sci Rep
Shah R, Bansal D, Rastogi P, Sachdev S, Devi N, Sharma RR, Sachdeva N, Agrawal A, Das L, Chanson P, Dutta P.   +10 more
europepmc   +1 more source

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

Advanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan, Runze Yang, Ting Zhou, Tianhao Xu, Yongqi Li, Yuelin Hu, Minghao Ge, Lei Zhang, Xiong Lu, Chaoming Xie, Weili Fu   +10 more
wiley   +1 more source

Insulin-like growth factor 2 as a central regulator of growth and metabolic efficiency in livestock: Genetic, nutritional, and biotechnological perspectives. [PDF]

Vet World
Ayuti SR, Kim EJ, Shin S, Lamid M, Lokapirnasari WP, Arif MAA, Warsito SH, Rosyada ZNA, Khairullah AR, Ferasyi TR, Sabri M, Rimayanti R, Wasito W, Ahmad RZ.   +13 more
europepmc   +1 more source

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

Advanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin, Yulong Hong, Chengliang Yin, Wanyang Guo, Yaxuan Wang, Ruijiang Zeng, Ruilin Liu, Zexian Ding, Xinlin Liu, Shangqing Ren, Qiyang Liang, Yaohui Wang, Xu Zhang, João Conde, Yuan Li, Xin Ma, Liangyou Gu   +16 more
wiley   +1 more source

Insulin-like Growth Factor 1 Ameliorates Intestinal Barrier Dysfunction in MASLD via IGF-1R/PI3K/AKT Signaling. [PDF]

Nutrients
Zhao W, San J, Jiang F, Zhu Y, Wu G, Yang J, Li W.   +6 more
europepmc   +1 more source

Dynamic Self‐Clickable Decellularized Matrix Hydrogels for Regulating Vascularity and Enhancing Muscle Regeneration

Advanced Science, EarlyView.
Dynamic decellularized hydrogels are prepared using bovine decellularized small intestine submucosa (SIS) norbornene (dSIS‐NB). Bovine dSIS contained significant amounts of disulfide‐rich fibrillin‐I, enabling ‘self‐clickable’ thiol‐norbornene gelation and spatiotemporal tuning of hydrogel physicochemical properties.
Van Thuy Duong, Tuba Marjan, Ngoc Ha Luong, Taimoor H. Qazi, Chien‐Chi Lin   +4 more
wiley   +1 more source

Insulin-like growth factor 1 receptor correlates with verbal memory in ILAE type 2 hippocampal sclerosis. [PDF]

Epilepsia
Cruz H, de Oliveira-Júnior AB, Cortez AFG, Saute RL, Centeno RS, Stávale JN, Guaranha MSB, Yacubian EMT, Cavalheiro EA, Leite JP, Peixoto-Santos JE.   +10 more
europepmc   +1 more source

Intestinal Source Control of Lipid Metabolism by Enzyme‐Probiotic Encapsulated, Spatiotemporal Crosslinked, and Small Intestine‐Adhesive Hydrogel Microspheres

Advanced Science, EarlyView.
A thiol‐modified alginate hydrogel microsphere‐encapsulated enzyme‐probiotic biohybrid (AKK‐COD) system has been developed to address the spatiotemporal delivery and colonization challenges of small intestine‐targeted probiotic for lipid metabolism regulation. The system exerts sequential functions of intragastric protection, small intestinal adhesion,
Xiaolin Wu, Weiwen Liang, Siqi He, Guangyuan Chen, Hui Zhou, Xinglong Wang, Yifei Li, Dingcai Wu, Bingna Zheng, Ruoxu Dou, Rongkang Huang   +10 more
wiley   +1 more source

Correction to "Interoceptive Information of Physical Vigor Through Circulating Insulin-Like Growth Factor 1". [PDF]

FASEB Bioadv
europepmc   +1 more source

Circulating levels of insulin-like growth factor I (IGF-I) and risk of multiple myeloma: An observational and Mendelian randomisation study. [PDF]

Br J Haematol
Benavente Y, Hermosa S, Papadimitriou N, Clay-Gilmour A, Brown EE, Hofmann JN, Rothman N, Lan Q, Berndt SI, Albanes D, Purdue M, Machiela MJ, Chanock SJ, Bhatti P, Cozen W, Norman A, Slager SL, Cerhan JR, Rajkumar V, Kumar SK, Vachon CM, Novak AJ, Habermann TM, Link BK, Salles G, Ghesquieres H, Bracci PM, Holly E, Griffin RG, Hildebrandt MAT, Vermeulen RCH, Kolijn PM, Hjalgrim H, Smedby KE, Jayasekara H, Cheah S, Monnereau A, Chen Y, Arslan A, Zhang Y, Camp NJ, Sborov DW, Osman AEG, Ziv E, De Vivo I, Joseph V, Teras LR, Patel AV, Kane E, Vajdic CM, Guilloteau A, Cocco P, Alemany L, Sainz J, McKay J, Birmann BM, Casabonne D.   +56 more
europepmc   +1 more source