Results 201 to 210 of about 13,071,502 (301)

Single Nucleotide Polymorphisms of Growth Hormone and Insulin-Like Growth Factor-1 Genes and Their Association With Growth Traits of Goats: A Systematic Review. [PDF]

Vet Med Sci
Makamu TC, Tyasi TL, Mabelebele M.
europepmc   +1 more source

Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix

Advanced Science, EarlyView.
Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi, Xiaojing Hao, Yi Yan, Fengyang Li, Yaru Zhang, Zixin Li, Wenjuan Xie, Jiayin Lu, Xiaomao Luo, Yanjun Dong, Haidong Wang, Juan Wang   +11 more
wiley   +1 more source

Combination of Voluntary Wheel Running and Oral Intake of Lactate Improves Object and Spatial Recognition Memory in Association With Hippocampal Insulin-Like Growth Factor-1 in Mice. [PDF]

Food Sci Nutr
Ota M, Esaki N, Sahara K, Matsui T, Tsuda T.   +4 more
europepmc   +1 more source

Dual‐Organelle Secretome Conjugation and Organ‐Uptake Tracking (DuO‐SCOUT) Enables Deep and Sensitive Mapping of the Secreted Proteins

Advanced Science, EarlyView.
A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang, Rui Qian, Jiaxing Song, Xingqi Meng, Jin Young Kim, Kwok On Lai, Li Wang, Liang Zhang   +7 more
wiley   +1 more source

Correction to "Interoceptive Information of Physical Vigor Through Circulating Insulin-Like Growth Factor 1". [PDF]

FASEB Bioadv
europepmc   +1 more source

Circulating levels of insulin-like growth factor binding protein 7 are associated with risks of chronic diseases and death. [PDF]

NPJ Aging
Li Z, Tao C, Zhou Z, Pollak MN, Giovannucci EL, Song M.   +5 more
europepmc   +1 more source

Encapsulated Leptin‐Producing Cells Facilitate Entrainment of Circadian Rhythms in Rodents and Nonhuman Primates

Advanced Science, EarlyView.
A clinically translatable cell line can be engineered to produce leptin, encapsulated in biomaterial and safely implanted to produce and deliver the metabolic regulating protein within the body. Implantation of these encapsulated cells decreases the time it takes for mice and non‐human primates to adjust to circadian disruptions similar to those ...
Samantha T. Fleury, Xuanyi Lin, Peter D. Rios, Christopher Olker, Eun Joo Song, Alejandra Cobos Perez, Cody Fell, Daisy Lopez, Ira Joshi, Hafsa Nasir, Cecelia Curtis, Danna Muringi, Kaiyuan Wang, José Oberholzer, Fred W. Turek, Isaac B. Hilton, Jonathan Rivnay, Martha Hotz Vitaterna, Omid Veiseh   +18 more
wiley   +1 more source

Insulin-like growth factor 1 receptor regulates breast cancer cell adhesion through beta-1 integrin. [PDF]

Front Endocrinol (Lausanne)
Galifi CA, Dogan E, Almansa LF, Maingrette K, Shah SS, Bulatowicz JJ, Ebenezer K, Herbig U, Miri AK, Wood TL.   +9 more
europepmc   +1 more source

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

Advanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang, Huimin Jiang, Chenyang Xiong, Xindi Zhou, Qinqin Tan, Han Xiao, Lan Qiu, Chun Gan, Yaxi Chen, Haiping Yang, Wei Jiang, Qiu Li   +11 more
wiley   +1 more source

Insulin-like growth factor 2 as a central regulator of growth and metabolic efficiency in livestock: Genetic, nutritional, and biotechnological perspectives. [PDF]

Vet World
Ayuti SR, Kim EJ, Shin S, Lamid M, Lokapirnasari WP, Arif MAA, Warsito SH, Rosyada ZNA, Khairullah AR, Ferasyi TR, Sabri M, Rimayanti R, Wasito W, Ahmad RZ.   +13 more
europepmc   +1 more source