Results 101 to 110 of about 622,044 (300)

Insulin-like growth factor - Oestradiol crosstalk and mammary gland tumourigenesis [PDF]

, 2013
Development and differentiation of the mammary gland are dependent on the appropriate temporal expression of both systemically acting hormones and locally produced growth factors.
Adamo, Ahmed, Ahn, Akekawatchai, Arteaga, Arteaga, Arteaga, Atsriku, Baege, Barone, Beattie, Becker, Bentel, Blakesley, Boylan, Burrows, Butt, Carboni, Carmeci, Casa, Castoria, Chen, Chen, Christopher Twelves, Clarke, Cui, Cullen, Davidson, De Leon, De Leon, De Leon, De Leon, De Marco, Dickson, Dubois, Espelund, Fagan, Fan, Figueroa, Fontana, Foulstone, Fowler, Fox, Freed, Furlanetto, Gaben, Gee, Genua, Ghayad, Gibson, Goldstein, Gooch, Goodwin, Gualberto, Hermani, Huff, Huynh, Huynh, Huynh, James Beattie, Jiralerspong, Joel, Kahlert, Kamanga-Sollo, Karey, Kato, Kim, Klotz, Knowlden, Koos, Lee, Lee, Leong, Levin, Lippman, Manni, Maor, Martin, Martin, Massarweh, Mathieu, Mawson, Maxwell, McCaig, McCotter, McGuire, McIntosh, Medunjanin, Mendoza, Milazzo, Minuto, Morelli, Morgan, Muck, Murphy, Murphy, Murphy, Naing, Neuenschwander, Oh, Osborne, Osborne, Osborne, Pandini, Panno, Parisot, Peng, Perks, Perks, Phillips, Picard, Pollak, Pratt, Pritchard, Prossnitz, Reem El-Gendy, Richards, Robertson, Rohlik, Rowzee, Ruan, Sachdev, Salahifar, Sano, Santen, Sheikh, Sheikh, Sheikh, Shukla, Siddle, Simoncini, Sisci, Song, Song, Song, Song, Stewart, Tharakan, Thomas, Thorsen, Tian, Tremblay, Tsonis, Valerie Speirs, van den Berg, Westley, Wilson, Wiseman, Yang, Yee, Yee, Yee, Yee, Yee, Yee, Yousef Hawsawi, Zapf   +156 more
core   +1 more source

Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues

Advanced Healthcare Materials, EarlyView.
Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman, Hadas Oved, Itay Gil, Amgad Marzook, Ester Sapir Baruch, Yahel Shechter, Assaf Shapira, Tal Dvir   +7 more
wiley   +1 more source

Effect of Six Months of Aerobic Exercise on Serum Levels of Insulin, Growth Hormone and Insulin-Like Growth Hormone 1 in Sedentary Obese Women

Medical Laboratory Journal, 2018
Background and Objectives: Inactivity, obesity and hormone disorders can lead to various diseases in obese and non-athletic individuals. The objective of this study was to investigate effects of six months of aerobic exercise on serum levels of insulin ...
Mahtab Moazami, Babisan Askari
doaj  

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

The impact of exercise on growth factors in postmenopausal women: a systematic review and meta-analysis

BMC Women's Health
Background Aging results in many changes in health status, body composition, muscle strength, and, ultimately, functional capacity. These changes coincide with significant alterations in the endocrine system, such as insulin-like growth factor-1 (IGF-1 ...
Yasaman Nasir, Mohammad Reza Hoseinipouya, Hesam Eshaghi, Mohammad Hossein Rahimi   +3 more
doaj   +1 more source

Three‐Dimensional Ovary Model to Improve and Study Murine Follicle Growth

Advanced Healthcare Materials, EarlyView.
To develop new methods for fertility preservation in women, novel culture systems for small follicles need to be established. In this work, a poly(ethylene glycol) based scaffold, with appropriate mechanical and bioactive features to support mouse follicle and ovary cell growth is developed, and the formed cell‐follicle interactions are visualized ...
Mira Jacobs, Valon Gllareva, Lukas Moser, Silvia Pravato, Eric Mora Pimentel, Brigitte Leeners, Martin Ehrbar   +6 more
wiley   +1 more source

Evaluating Serum Insulin-Like Growth Factor 1 and Insulin-Like Growth Factor Binding Protein 3 as Markers in Prostate Cancer Diagnosis

The International Journal of Biological Markers, 2016
Background Prostate-specific antigen (PSA) lacks specificity and sensitivity in discriminating prostate cancer (PCa) from benign prostatic hyperplasia (BPH) when the total PSA (tPSA) level is between 4 and 10 ng/mL.
Giulia Rainato, Aline S.C. Fabricio, Matelda Zancan, Lucia Peloso, Ruggero Dittadi, Mario Barichello, Andrea Fandella, Vincenzo Scattoni, Massimo Gion   +8 more
doaj   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source

Causal associations between the insulin-like growth factor family and sarcopenia: a bidirectional Mendelian randomization study

Frontiers in Endocrinology
ObjectiveInsulin-like growth factor (IGF) is closely associated with sarcopenia, yet the causal relationship of this association remains unclear.
Jili Liu, Meng Chen, Xin Xia, Zhaolin Wang, Yanqin Wang, Ling Xi   +5 more
doaj   +1 more source

Astrocytic Insulin-Like Growth Factor-1 Protects Neurons Against Excitotoxicity

Frontiers in Cellular Neuroscience, 2019
BackgroundExogenous insulin like growth factor-1 (IGF-1) is known to be neuroprotective in animal models with brain insults, while it can also cause hyperexcitability in rodents.
Wei Chen, Bin He, Wusong Tong, Jinsong Zeng, Ping Zheng   +4 more
doaj   +1 more source